Abstract:Both pressure control ventilation and volume control ventilation with a decelerating flow waveform provided better oxygenation at a lower peak inspiratory pressure and higher mean airway pressure compared to volume control ventilation with a square flow waveform. The results of our study suggest that the reported advantages of pressure control ventilation over volume control ventilation with a square flow waveform can be accomplished with volume control ventilation with a decelerating flow waveform.
“…Comparison of volume control and pressure control ventilation using a tidal volume of 10 ml/kg, respiratory frequency to maintain a pH >7.30 and PaCO 2 <50 mmHg, and positive end-expiratory pressure, (PEEP) set to maintain PaO 2 > 70 mmHg or SaO 2 > 93% with an FiO 2 ≤0.50 was done by Davis K Jr et al and they concluded that both pressure controlled ventilation and volume controlled ventilation with a decelerating flow waveform provided better oxygenation at a lower peak inspiratory pressure and higher mean airway pressure compared to volume controlled ventilation with a square flow waveform. 15 The results were similar to our study with better oxygenation and lower peak inspiratoy pressures in pressure controlled ventilation than volume controlled ventilation. In a study on laparoscopic gastric banding surgeries for obesity by Cadi P et al, pressure controlled ventilation improved oxygenation as compared to volume controlled in morbidly obese patients.…”
“…Comparison of volume control and pressure control ventilation using a tidal volume of 10 ml/kg, respiratory frequency to maintain a pH >7.30 and PaCO 2 <50 mmHg, and positive end-expiratory pressure, (PEEP) set to maintain PaO 2 > 70 mmHg or SaO 2 > 93% with an FiO 2 ≤0.50 was done by Davis K Jr et al and they concluded that both pressure controlled ventilation and volume controlled ventilation with a decelerating flow waveform provided better oxygenation at a lower peak inspiratory pressure and higher mean airway pressure compared to volume controlled ventilation with a square flow waveform. 15 The results were similar to our study with better oxygenation and lower peak inspiratoy pressures in pressure controlled ventilation than volume controlled ventilation. In a study on laparoscopic gastric banding surgeries for obesity by Cadi P et al, pressure controlled ventilation improved oxygenation as compared to volume controlled in morbidly obese patients.…”
“…For the same V T , the same inspiratory time, and a descending ramp of flow with VCV, the differences in P aO 2 between PCV and VCV are trivial. 22 Experimental models of ALI/ARDS suggest that the high initial flow that occurs with PCV might be injurious rather than lung-protective. [23][24][25] Whether synchrony is better with PCV than VCV is also debatable.…”
Section: Pressure Controlled Versus Volume Controlled Ventilationmentioning
To minimize ventilator-induced lung injury, attention should be directed toward avoidance of alveolar over-distention and cyclical opening and closure of alveoli. The most impressive study of mechanical ventilation to date is the Acute Respiratory Distress Syndrome (ARDS) Network study of higher versus lower tidal volume (V T ), which reported a reduction in mortality from 39.8% to 31.0% with 6 mL/kg ideal body weight rather than 12 mL/kg ideal body weight (number-neededto-treat of 12 patients). To achieve optimal lung protection, the lowest plateau pressure and V T possible should be selected. What is most important is limitation of V T and alveolar distending pressure, regardless of the mode set on the ventilator. Accumulating observational evidence suggests that V T should be limited in all mechanically ventilated patients-even those who do not have ALI/ARDS. Evidence does not support the use of pressure controlled inverse-ratio ventilation. Although zero PEEP is probably injurious, an area of considerable controversy is the optimal setting of PEEP. Available evidence does not support the use of higher PEEP, compared to lower PEEP, in unselected patients with acute lung injury (ALI)/ARDS. However, results of a metaanalysis using individual patients from 3 randomized controlled trials suggest that higher PEEP should be used for ARDS, whereas lower PEEP may be more appropriate in patients with ALI. PEEP should be set to maximize alveolar recruitment while avoiding over-distention. Many approaches for setting PEEP have been described, but evidence is lacking that any one approach is superior to any other. In most, if not all, cases of ALI/ARDS, conventional ventilation strategies can be used effectively to provide lung-protective ventilation strategies.
“…They found that PCV and VCV with a decelerating waveform lead to a lower PIP yet also to a higher mean airway pressure when compared with VCV with a square waveform. 19 A decelerating flow pattern (as is generated in PCV mode) is met with less flow resistance than the constant flow pattern of VCV, meaning that less airway pressure is generated and PIP is lower; however the decelerating pattern does tend to lead to higher mean airway pressures. 20 Unfortunately in our study we had no facility for measuring the mean airway pressure, so it is possible that despite generating a higher PIP, VCV may have produced equal or lower mean airway pressures.…”
Optimal mechanical ventilation of the pregnant ewe during anaesthesia is of vital importance for maintaining fetal viability. This study aimed to compare peak inspiratory pressure (PIP), oxygenation and cardiovascular parameters with pressure-control (PCV) or volume-control (VCV) mechanical ventilation of anaesthetized pregnant sheep. Twenty ewes at 110 days gestation underwent general anaesthesia in dorsal recumbency for fetal surgery in a research setting. All the sheep were mechanically ventilated; one group with PCV (n ¼ 10) and another with VCV (n ¼ 10) to maintain normocapnia. PIP, direct arterial blood pressure, heart rate, arterial pH and arterial oxygen tension were recorded. PIP was lower in the PCV group (P < 0.001). Arterial oxygen tension was higher in the PCV group (P ¼ 0.013). Mean and diastolic pressures were lower in the PCV group (P ¼ 0.029 and P ¼ 0.047, respectively). Both VCV and PCV provide adequate oxygenation of pregnant sheep anaesthetized in dorsal recumbency, though PCV may provide superior oxygenation at a lower PIP.
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