“…In fact, medium polarity solvents (diethyl ether, dichloromethane or ethyl acetate) extract more polar and higher MW compounds such as hexadecanal (Naef and Velluz, 2001; Gancel et al, 2002; Chisholm et al, 2003a,b; Cannon et al, 2015), squalene (Cheong et al, 2011b; Jiang et al, 2011), linoleic acid (Cheong et al, 2011b, 2012; Jiang et al, 2011), heptadecanoic acid (Delort and Jaquier, 2009; Jiang et al, 2011) or neophytadiene (Delort and Jaquier, 2009; Delort et al, 2015) than distillation or cold press extraction, and it fails to extract many monoterpene and sesquiterpene compounds which are characteristic of Citrus EOs (Jiang et al, 2011). Moreover, there are other minority extraction methods that use also organic solvents such as simultaneous distillation and extraction (SDE) (Akakabe et al, 2008; Kerdchoechuen et al, 2010; Sun et al, 2014a), microwave-assisted extraction (MAE) (Sun et al, 2014a; Liu et al, 2015), and ultrasonic-assisted extraction (UAE) (Alissandrakis et al, 2003; Darjazi, 2011b; Liu et al, 2012; Sun et al, 2014a; Zhang et al, 2017).…”