Comparison of Vascular Response After Sirolimus-Eluting Stent Implantation Between Patients With Unstable and Stable Angina Pectoris

Kubo, Takashi; Imanishi, Toshio; Kitabata, Hironori; Kuroi, Akio; Ueno, S.; Yamano, Takashi; Tanimoto, Takashi; Matsuo, Yoshiki; Mizutani, Takashi; Takarada, Shigeho; Tanaka, Atsushi; Nakamura, Nobuo; Mizukoshi, Masato; Tomobuchi, Yoshiaki; Akasaka, Takashi

doi:10.1016/j.jcmg.2008.03.012

Cited by 154 publications

(114 citation statements)

References 19 publications

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“…and tissue protrusion 70,71) in higher frequency compared to IVUS. 72,73) OCT is capable of detecting smaller stent edge dissection (Fig. 3A) than IVUS, 74) but OCT-detected stent edge dissection is not associated with the clinical events.…”

Section: Evaluation Of Non-culprit Plaque Characteristicsmentioning

confidence: 92%

“…3A) than IVUS, 74) but OCT-detected stent edge dissection is not associated with the clinical events. [73][74][75][76][77] Incomplete stent apposition (Fig. 3B) may be related to persistent malapposition, 75) or delayed neointimal coverage, 78) but small incomplete stent apposition is not related to clinical events.…”

Section: Evaluation Of Non-culprit Plaque Characteristicsmentioning

confidence: 99%

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Optical Coherence Tomography for Study of <i>In Vivo</i> Pathobiology and for Optimization of Percutaneous Coronary Intervention

Sugiyama

Jang

2017

Angioscopy

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Intravascular optical coherence tomography (OCT) is an imaging modality uniquely characterized by its high resolution. OCT can visualize in vivo plaque characteristics and detect vulnerable plaque, such as thin-cap fibroatheroma, which has a large lipid pool with overlying thin fibrous cap. OCT can also help the clinicians to identify the underlying pathology of acute coronary syndrome: plaque rupture, plaque erosion, and calcified nodule. The OCT system enables automated measurement of the lumen diameter, lumen area, and lesion length, which is useful to determine appropriate reference sites, stent size and stent length during percutaneous coronary intervention (PCI). Evaluation of underlying plaque characteristics is helpful in predicting possible complications after PCI. OCT-guided PCI may acquire comparable angiographical and clinical outcomes to intravascular ultrasound-guided PCI. OCT can be used to evaluate characteristics of non-culprit plaque and efficacy of lipidlowering therapy on plaque stabilization. OCT also clearly visualizes mechanical vessel injury after stent implantation. Notably, the presence of irregular tissue protrusion has been shown to be associated with the occurrence of device-oriented clinical events. Recent studies suggest that OCT is feasible for the selection of conservative management without stenting in patients with acute coronary syndrome caused by plaque erosion.

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Section: Evaluation Of Non-culprit Plaque Characteristicsmentioning

confidence: 92%

Section: Evaluation Of Non-culprit Plaque Characteristicsmentioning

confidence: 99%

Optical Coherence Tomography for Study of <i>In Vivo</i> Pathobiology and for Optimization of Percutaneous Coronary Intervention

Sugiyama

Jang

2017

Angioscopy

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“…In OCT, plaque protrusion is characterized by a smooth surface and no signal attenuation, and thrombus protrusion by an irregular surface and significant signal attenuation. Tissue protrusion is frequently observed in the culprit lesion of acute coronary syndrome, because the unstable lesion contains soft lipid tissue and thrombi 19 (Figure 3). At present, a significant OCT in PCI for in-stent restenosis.…”

Section: Tissue Protrusionmentioning

confidence: 99%

“…19 Coronary dissection is easier to observe at the distal stent edge because of the stent-vessel diameter mismatch. When there is no narrowing of the true lumen, an additional procedure may not be required for the treatment of coronary dissection.…”

Section: Coronary Dissectionmentioning

confidence: 99%

Application of Optical Coherence Tomography in Percutaneous Coronary Intervention

Kubo

Tanaka

Kitabata

et al. 2012

Circ J

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“…[12][13][14][15][16] In addition, plaque type and morphology prior to intervention significantly influence the long-term procedure outcome. 17 The parameters that influence plaque vulnerability include the thickness of the fibrous cap overlying the necrotic core, inflammation, intraplaque haemorrhage, and composition. 10,18 Data on plaque composition and stability, complementing the image, may inform the decision on if and how to treat a particular section of coronary artery.…”

mentioning

confidence: 99%

Imaging atherosclerotic plaque composition with intracoronary optical coherence tomography

Soest

Goderie²,

Gonzalo³

et al. 2009

NHJL

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Optical coherence tomography (OCT) allows highly accurate diagnosis of atherosclerotic plaques, including measurement of the thickness of fibrous caps, permitting an assessment of the risk of rupture. While the OCT image presents morphological information in highly resolved detail, it relies on interpretation by trained readers for the identification of tissue type. We developed a method for quantitative classification of atherosclerotic plaque constituents. The optical attenuation coefficient µ t distinguishes different tissue types: necrotic core and macrophage infiltration exhibit strong attenuation, µ t ≥10 mm -1 , while calcific and fibrous tissue have a lower µ t ≈2-5 mm -1 . (Neth Heart J 2009;17:448-50.)Keywords: atherosclerosis, optical coherence tomography, intravascular imaging, tissue characterisation I t is generally accepted that the majority of acute coronary events are precipitated by the rupture of a vulnerable atherosclerotic plaque in the coronary system, and subsequent thrombogenesis. 1-3 The thin-cap fibroatheroma is currently hypothesised to be the most likely class of arterial wall pathology to constitute a vulnerable plaque. 4,5 The key to plaque vulnerability is still elusive, 7 even though recent technological advances in intravascular imaging technology have enabled the collection of a wealth of data on unstable atherosclerosis in all its stages of development, 8 both in clinical and in ex vivo settings. It appears very likely that combined information on physiological, anatomical, chemical, and mechanical parameters 9-11 is needed for a reliable assessment of the proneness of a specific lesion to rupture. Some of these parameters may be accessible through intravascular imaging methods. [12][13][14][15][16] In addition, plaque type and morphology prior to intervention significantly influence the long-term procedure outcome. 17 The parameters that influence plaque vulnerability include the thickness of the fibrous cap overlying the necrotic core, inflammation, intraplaque haemorrhage, and composition. 10,18 Data on plaque composition and stability, complementing the image, may inform the decision on if and how to treat a particular section of coronary artery.Optical coherence tomography (OCT) 19 is rapidly becoming the method of choice for assessing arterial wall pathology in vivo. It has an image resolution of about 10 to 15 µm, an order of magnitude better than intravascular ultrasound. Atherosclerotic plaques can be diagnosed with high accuracy, 20 including measurement of the thickness of fibrous caps, 21 moving a step towards in vivo assessment of the risk of rupture. Insight into the physiology of a plaque is complementary to the structural information offered by the OCT greyscale image.While the OCT image presents morphological information in highly resolved detail, it relies on interpretation of the images by trained readers for the identification of vessel wall components and tissue type. We have developed a framework to aid the recognition of these atherosclerotic plaque const...

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Comparison of Vascular Response After Sirolimus-Eluting Stent Implantation Between Patients With Unstable and Stable Angina Pectoris

Cited by 154 publications

References 19 publications

Optical Coherence Tomography for Study of <i>In Vivo</i> Pathobiology and for Optimization of Percutaneous Coronary Intervention

Optical Coherence Tomography for Study of <i>In Vivo</i> Pathobiology and for Optimization of Percutaneous Coronary Intervention

Application of Optical Coherence Tomography in Percutaneous Coronary Intervention

Imaging atherosclerotic plaque composition with intracoronary optical coherence tomography

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