Comparison of Vaginal Misoprostol Versus Sublingual Misoprostol in First Trimester Medical Termination of Pregnancy

Abstract

Medical termination of pregnancy for various indications was legalized in India in 1971.The NHM guidelines issued in the MMA handbook in 2016 recommends mifepristone 200mg and misoprostol 800 g for medical termination of pregnancy before 49 days from the last menstrual period. Misoprostol can be administered by oral, buccal, ublingual or vaginal route, with each route having its own advantages and disadvantages. We have conducted this study on 200 women desiring MTP to compare efficacy of vaginal and sublingual routes of administration of misoprostol. Our study concluded that sublingual misoprostol was more effective for early first trimester MTP compared to vaginal misoprostol.