Comparison of Ultrasound and Magnetic Resonance Urography for Evaluation of Contralateral Kidney in Patients With Multicystic Dysplastic Kidney Disease

Kalisvaart, Jonathan F.; Bootwala, Yasmin; Poonawala, Husain; Elmore, James M.; Kirsch, Andrew J.; Scherz, Hal C.; Jones, Richard A.; Grattan‐Smith, J. Damien; Smith, Edwin A.

doi:10.1016/j.juro.2011.04.105

Cited by 13 publications

(11 citation statements)

References 16 publications

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“…Those authors held that high blood pressure was quite common in children with MCDK, and the high blood pressure could be mitigated (12). Their findings were consistent with those of other authors (13–15). Seeman et al identified dynamic blood pressure in 25 MCDK children and found that the blood pressure of 5 cases (20%) was above the 95th percentiles, and there were 2 cases that suffered from high blood pressure both during the day and night, while the other 3 cases suffered from high blood pressure solely during the night (16).…”

Section: Introductionsupporting

confidence: 94%

Minimally invasive open nephrectomy on children with multicystic dysplastic kidney

Feng

Zhu

Sun

et al. 2016

Experimental and Therapeutic Medicine

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The aim of the study was to summarize the preliminary experience of minimally invasive open nephrectomy operation on children with multicystic dysplastic kidney (MCDK). A retrospective review was performed on the clinical materials of the 15 children that had accepted consecutive minimally invasive open nephrectomies during the previous 2 years. The enrolled children were diagnosed with unilateral MCDK under computed tomography, emission computerized tomography and ultrasound and no anomaly in the contralateral functioning kidney was found. Of the 15 children, 12 were boys and 3 were girls, with 5 cases on the right and 10 cases on the left. Operations were completed at the retroperitoneal space in order to open an incision on the waists and ribs of the children, the length of which ranged from 1.5 to 2.0 cm (average 1.7 cm). The age of the children at operation ranged from 3 months to 5.6 years old, with an average of 2.4 years old. Surgery lasted for 30–50 min, with an average of 34.6 min. The estimated blood loss of each child was <5 ml. After operation, prophylactic intravenous antibiotics were administered for 2–4 days to prevent infection. All of the operations proved very successful. Following surgery the children were hospitalized for 2–4 days for observation, with an average of 2.8 days. No complications occurred during the follow-up period. In conclusion, minimally invasive open nephrectomy is effective for children with MCDK. The procedure is superior with regard to operative time, cosmesis, and length of stay. It is a safe and effective treatment choice for patietns with MCDK and can be easily performed on children.

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Section: Introductionsupporting

confidence: 94%

Minimally invasive open nephrectomy on children with multicystic dysplastic kidney

Feng

Zhu

Sun

et al. 2016

Experimental and Therapeutic Medicine

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“…3,4 Vesicoureteral reflux and the resulting urinary tract infections can cause renal damage and possibly renal failure of the only functional kidney. 6,8,9 Although sonography is the preferred imaging modality for MCDK, other types of imaging and physiological testing are usually performed due to other health issues linked to MCDK. The American College of Radiology (ACR) ranks the appropriateness of certain imaging tests for chronic renal failure, and sonography is ranked as the most appropriate.…”

Section: Discussionmentioning

confidence: 99%

“…10 An alternate imaging examination that can be performed on patients with MCDK postnatally is the voiding cystourethrogram, a specialized radiographic procedure that evaluates for VUR. 8,9 This test involves placing a catheter into the patient's bladder and filling the bladder with a contrast medium. The catheter is then removed, and a series of fluoroscopic images are taken of the bladder, kidneys, and ureters as the patient's bladder is emptied.…”

Section: Discussionmentioning

confidence: 99%

“…Although typically lower ranked by the ACR, the dimercaptosuccinic acid scan uses radioactive tracers to evaluate the kidneys for size, function, and scarring related to reflux of urine from the bladder. 8,9 Magnetic resonance urography can be used to determine the presence of VUR in the presence of MCDK while also evaluating the structure and the function of the unaffected kidney. 9 The prognosis for patients with MCDK is very good since most of the affected kidneys will eventually become smaller as the cysts gradually involute.…”

Section: Discussionmentioning

confidence: 99%

“…8,9 Magnetic resonance urography can be used to determine the presence of VUR in the presence of MCDK while also evaluating the structure and the function of the unaffected kidney. 9 The prognosis for patients with MCDK is very good since most of the affected kidneys will eventually become smaller as the cysts gradually involute. 2,4 Follow-up management for patients with MCDK involves having at least annual renal sonograms (with renal Doppler) of the functioning kidney.…”

Section: Discussionmentioning

confidence: 99%

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Multicystic Dysplastic Kidney and Sonography

Baker

Goepfert

Whitney

2016

Journal of Diagnostic Medical Sonography

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Multicystic dysplastic kidney is a congenital anomaly that can affect the kidneys. It is generally unilateral and is characterized by multiple noncommunicating cysts in the renal parenchyma. This disease usually results in an enlarged, nonfunctioning kidney in the neonate. Recent advances in diagnostic medical imaging, especially in sonography, have enabled earlier detection of this disease, created better management and treatment options, and resulted in improved outcomes for patients. This case study demonstrates the use of early detection with sonography and the utilization of it for follow-up care. Sonography is ranked as the imaging modality of choice for patients with a clinical condition of renal failure and has the potential for an improved outcome for patients.

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Utility of renal scintigraphy in diagnosis of multicystic dysplastic kidney

Hannallah

Baker

Filippo

et al. 2022

J of Clinical Ultrasound

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Purpose To compare the prevalence of vesicoureteral reflux (VUR), febrile urinary tract infection (fUTI), and chronic kidney disease (CKD) among patients with multicystic dysplastic kidney (MCDK) diagnosed by renal scintigraphy (RS) versus follow‐up renal ultrasound (RUS) alone. Methods This was a retrospective review of patients seen at a tertiary care center from 2010 to 2020 with MCDK diagnosed by RS or follow‐up RUS. Differences in the prevalence of VUR, fUTI, and CKD by cohort were assessed using logistic regression analysis, Pearson X2, and Fisher's Exact tests. Temporal trends in diagnostic methods used (RUS versus RUS + RS) were evaluated using the Cochran‐Armitage trend test. Results One‐hundred seventy‐two patients were included: 50% (n = 86) underwent RUS + RS and 50% (n = 86) underwent RUS alone to diagnose MCDK. Prevalence of VUR, fUTI, and CKD did not significantly vary between groups. Among patients who had a VCUG, 4.4% had contralateral VUR (1.7% RUS + RS group; 7.4% RUS group; p = 0.19) and 14.5% had at least one fUTI (16.3% RUS + RS group; 12.8% RUS group; p = 0.52). Females were significantly more likely to have at least one fUTI (p = 0.04). Four patients (2.3%) developed CKD, all in the RUS + RS cohort (p = 0.12). Diagnosis of MCDK by RUS versus RUS + RS did not significantly vary over time (p = 0.17). Conclusion Patients with unilateral MCDK confirmed by RS versus RUS alone do not significantly vary in the prevalence of VUR, fUTI, or CKD. Renal scintigraphy studies may not be necessary in unilateral MCDK diagnosis but continue to be used.

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Comparison of Ultrasound and Magnetic Resonance Urography for Evaluation of Contralateral Kidney in Patients With Multicystic Dysplastic Kidney Disease

Cited by 13 publications

References 16 publications

Minimally invasive open nephrectomy on children with multicystic dysplastic kidney

Minimally invasive open nephrectomy on children with multicystic dysplastic kidney

Multicystic Dysplastic Kidney and Sonography

Utility of renal scintigraphy in diagnosis of multicystic dysplastic kidney

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