Comparison of two ultra-widefield imaging for detecting peripheral retinal breaks requiring treatment

Kumar, Jayant; Kohli, Piyush; Babu, Naresh; Krishnakumar, Krishin; Arthur, Dhipak; Ramasamy, Kim

doi:10.1007/s00417-020-04938-8

Cited by 9 publications

(15 citation statements)

References 22 publications

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“…According to Kumar et al, 16 the lower sensitivity of the Zeiss Clarus 500 in the temporal quadrant could be attributed to a smaller field of vision acquired in the temporal quadrant as a result of a patient's nose interfering with rotating the body of the camera to capture images in the extreme temporal periphery. Similarly, in our study, the Optos P200dTx detected peripheral lesions in zone C3 better than the Zeiss Clarus 500.…”

Section: Discussionmentioning

confidence: 99%

Comparison of Two Ultra-Widefield Cameras With High Image Resolution and Wider View for Identifying Diabetic Retinopathy Lesions

Khan

Raman

Karamcheti

et al. 2021

Trans. Vis. Sci. Tech.

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Purpose To compare the effectiveness of the Optos P200dTx and Zeiss Clarus 500 fundus cameras in detecting diabetic retinopathy (DR) lesions. Methods A cross-sectional study was conducted among 243 patients with clinically diagnosed diabetes mellitus who were referred for an eye examination from two tertiary eye care centers in Chennai, India. Patients underwent DR screening based on mydriatic fundal images acquired by both fundal cameras. Fundal images from the two separate devices for each eye were compared based on accurately identified pathological retinal lesions with respect to type and location. Results When studying lesions of the central retina, they were better identified by the Zeiss Clarus compared with the Optos P200dTx, with six out of eight being statistically significant ( P < 0.05). However, lesions of the mid-peripheral retina and peripheral retina were better identified by the Optos P200dTx than the Zeiss Clarus, with three out of eight lesions and five out of eight lesions being statistically significant ( P < 0.05), respectively. Based on the color and size of lesions, the Optos P200dTx had a higher chance (59.6%) of missing white lesions than did the Zeiss Clarus (17%) ( P < 0.0001). Consequently, small- and medium-sized lesions were missed more by the Optos P200dTx (30.72% and 32.63%, respectively) than the Zeiss Clarus (22.3% and 19.30%, respectively). Conclusions The capability of detecting or missing a particular DR lesion among diabetics differed between the two cameras based on effective field of view, resolution, and the retinal zone being imaged. Translational Relevance The choice of which ultra-widefield camera to be used for screening DR can be based on the greater prevalence of central versus peripheral retinal lesions noted in the patient population seen in a clinical practice.

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Section: Discussionmentioning

confidence: 99%

Comparison of Two Ultra-Widefield Cameras With High Image Resolution and Wider View for Identifying Diabetic Retinopathy Lesions

Khan

Raman

Karamcheti

et al. 2021

Trans. Vis. Sci. Tech.

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“…[5][6][7][8] The detection and photodocumentation of peripheral retinal pathologies, especially those predisposing retinal detachment, were in demand in clinical practice. 9 Ultrawide field imaging (UWFI) uses ellipsoid mirror to obtain an unprecedented large-angle view of up to 200° without pupillary mydriasis and have achieved a wide application in diabetic retinopathy, 10 uveitis, 11 age-related macular degeneration 12 and myopia, 13 etc. It has a profound advantage over traditional retinal examinations like indirect binocular ophthalmoscope, Goldmann three mirror contact lens by providing image-based counselling for patients with peripheral retinal lesions.…”

Section: Introductionmentioning

confidence: 99%

Application of mydriasis and eye steering in ultrawide field imaging for detecting peripheral retinal lesions in myopic patients

Yang

Shen

et al. 2022

Br J Ophthalmol

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PurposeTo compare mydriatic and eye-steering ultrawide field imaging (UWFI) with standard non-mydriatic UWFI examination in detecting peripheral retinal lesions in myopic patients.MethodsCross-sectional, observational study. 220 eyes of 110 myopic patients with known peripheral retinal lesions in at least one eye under Goldmann three mirror contact lens examination were recruited. Non-mydriatic standard and eye-steering UWFI images were taken centrally and with eye-steering technique in upper, lower, nasal and temporal gazes under Optomap UWFI (Daytona, Optos, UK). Mydriatic standard and eye-steering UWFI was captured in central gaze and four different peripheral gazes. Sensitivity of detecting peripheral retinal lesions under different UWFI settings was compared.Results141 (64.09%) eyes were with peripheral retinal lesions. The sensitivity for detecting peripheral lesions from low to high was 41.84% (95% CI 33.62% to 50.54%) under non-mydriatic standard UWFI setting, 52.48% (95% CI 44.08% to 60.75%) under mydriatic standard setting, 75.18% (95% CI 67.21% to 82.06%) under non-mydriatic eye-steering setting and 86.52% (95% CI 79.76% to 91.69%) under mydriatic eye-steering setting. Both mydriasis and eye-steering technique increased sensitivity of detecting peripheral lesions with statistical significance (p<0.001). By applying eye-steering technique, sensitivity of detecting lesions located in superior and inferior quadrants witnessed a greater increase compared with other two quadrants (p<0.05). Neither spherical equivalence (p>0.05) nor axial length (p>0.05) was an independent influence factor for detecting peripheral lesions.ConclusionsEye-steering technique and mydriasis could both efficiently improve the sensitivity of detecting peripheral retinal lesions in myopic patients. Lesions of superior and inferior quadrants benefited more from eye-steering technique.

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“…Although the clinician should be aware of the possibility that a minority of the most peripheral lesions may be not entirely visualized, it might be considered a first line diagnostic modality, in the context of a full ophthalmological examination.The recent coronavirus disease 2019 (COVID-19) pandemic has forced the medical community to revise and reorganize the methods of clinical evaluation, particularly in ophthalmology: despite being the current gold standard for the examination of retinal periphery, indirect ophthalmoscopy, as well as central fundus biomicroscopy for macular disorders, require a close contact with the patient and need adequate time of evaluation 1-3 . The broad use of ultra-wide-field (UWF) fundus cameras has helped to partly overcome these obstacles, allowing: the clinician to analyze fundus images even at distance, namely in a different location than the clinic, to reduce the time of evaluation for the patient and the clinician; to perform screening for retinal disorders, such as diabetic retinopathy 4-6 and peripheral retinal lesions [7][8][9] . Fundus imaging can be considered UWF when covering a field of retina equal to 100° or more 4,7,[10][11][12] , showing, in a single shot, retinal features anterior to vortex vein ampullae in all four quadrants 13 .…”

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Ultra-wide-field fundus photography compared to ophthalmoscopy in diagnosing and classifying major retinal diseases

Midena

Marchione

Giorgio

et al. 2022

Sci Rep

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To analyze the performance of ultra-wide-field (UWF) fundus photography compared with ophthalmoscopy in identifying and classifying retinal diseases. Patients examined for presumed major retinal disorders were consecutively enrolled. Each patient underwent indirect ophthalmoscopic evaluation, with scleral depression and/or fundus biomicroscopy, when clinically indicated, and mydriatic UWF fundus imaging by means of CLARUS 500™ fundus camera. Each eye was classified by a clinical grader and two image graders in the following groups: normal retina, diabetic retinopathy, vascular abnormalities, macular degenerations and dystrophies, retinal and choroidal tumors, peripheral degenerative lesions and retinal detachment and myopic alterations. 7024 eyes of new patients were included. The inter-grader agreement for images classification was perfect (kappa = 0.998, 95% Confidence Interval (95%CI) = 0.997–0.999), as the two methods concordance for retinal diseases diagnosis (kappa = 0.997, 95%CI = 0.996–0.999) without statistically significant difference. UWF fundus imaging might be an alternative to ophthalmoscopy, since it allows to accurately classify major retinal diseases, widening the range of disorders possibly diagnosed with teleophthalmology. Although the clinician should be aware of the possibility that a minority of the most peripheral lesions may be not entirely visualized, it might be considered a first line diagnostic modality, in the context of a full ophthalmological examination.

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Comparison of two ultra-widefield imaging for detecting peripheral retinal breaks requiring treatment

Cited by 9 publications

References 22 publications

Comparison of Two Ultra-Widefield Cameras With High Image Resolution and Wider View for Identifying Diabetic Retinopathy Lesions

Comparison of Two Ultra-Widefield Cameras With High Image Resolution and Wider View for Identifying Diabetic Retinopathy Lesions

Application of mydriasis and eye steering in ultrawide field imaging for detecting peripheral retinal lesions in myopic patients

Ultra-wide-field fundus photography compared to ophthalmoscopy in diagnosing and classifying major retinal diseases

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