Comparison of two surgical techniques in the treatment of multiple gingival recessions sandwiched with a combination of A-PRF and L-PRF

Sameera, Shaik; M, Nagasri; Kumar, Pavuluri Aravind; Indeevar, P.; Raviraj, Kalapala; Musalaiah, Svvs

doi:10.1016/j.sdentj.2018.03.002

Cited by 15 publications

(10 citation statements)

References 22 publications

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“…Furthermore, the fibrin in PRF also provides a three-dimensional structure for stimulating the proliferation and differentiation of recruited cells [25]. PRF has been widely used in bone and cartilage defect repair, oral implants, and severe periodontitis, achieving satisfactory therapeutic results [26, 27]. However, fresh PRF (F-PRF) is commonly limited to use immediately after preparation and autologous applications, making it difficult to store and commercialize for long periods of time.…”

Section: Introductionmentioning

confidence: 99%

Preparation and effect of lyophilized platelet-rich fibrin on the osteogenic potential of bone marrow mesenchymal stem cells in vitro and in vivo

Wang

Han²,

Sun

et al. 2019

Heliyon

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ObjectivesThe goal of this study was to prepare lyophilized platelet-rich fibrin (L-PRF) and analyze the combined use of L-PRF and osteogenic bone marrow mesenchymal stem cell (BMSC) sheet fragments for bone tissue engineering via in vivo injection.MethodsFirst, fresh PRF (F-PRF) was lyophilized to prepare L-PRF, the characteristics of which were examined through gross morphological, and histological and microstructural observations. In addition, the kinetics of growth factor release from L-PRF and F-PRF were also determined by enzyme-linked immunosorbent assay (ELISA). Subsequently, after assessing the proliferation and osteogenic differentiation of BMSCs exposed to L-PRF or F-PRF in vitro, we subcutaneously injected BMSC sheet fragments with L-PRF or F-PRF into nude mice and assessed bone formation through microcomputed tomography and histological analyses.ResultsWe observed that L-PRF released growth factors that favored BMSC proliferation and osteogenic differentiation in vitro. The combined use of L-PRF and osteogenic BMSC sheet fragments enabled bone tissue regeneration in vivo, and no significant difference between the F-PRF and L-PRF groups was observed (P = 0.24).ConclusionsThe results of this study demonstrate that the combined use of L-PRF and osteogenic BMSC sheets may have potential in the fabrication of engineered bone.

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Section: Introductionmentioning

confidence: 99%

Preparation and effect of lyophilized platelet-rich fibrin on the osteogenic potential of bone marrow mesenchymal stem cells in vitro and in vivo

Wang

Han²,

Sun

et al. 2019

Heliyon

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“…(40) PRF has been effectively utilized to treat bone and cartilage defects, dental implants, and severe periodontitis, with significant treatment outcomes. (41,42)…”

Section: Mechanism Of Enhancing Healingmentioning

confidence: 99%

Platelet-rich fibrin to manage different periodontal defects combine with Flap surgery and other uses in dentistry. A descriptive review

Iqbal¹,

Mim

Shahabuddin

2021

Update Dent. Coll. j

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In these days, periodontal diseases are very much common in Asian subcontinent especially in Bangladesh, due to some relevant factors that is more prevalent in this country. Most of the time patient neglect their condition and ultimately loss their teeth. Even after doing phase 1 therapy that is scaling, polishing with antimicrobial agents, it could not heal the periodontal condition with advanced bone destruction or clinical attachment loss. Therefore, after proper oral hygiene maintenance therapy, different flap surgery should consider. . In recent study, it is found that platelet rich fibrin (PRF) PREPARED From the patient’s Own blood and then placement within defect could enhance the early healing procedure. This PRF membrane is also used in a variety of discipline in dentistry, including regenerative surgery. This PRF membrane is now used in a variety of disciplines in dentistry, including regenerative surgery and enhancing early healing. The goal of this study is to critically analyze and appraise the currently available research with an emphasis on the use of PRF in regenerative periodontal surgery. An electronic search was conducted (PubMed/MEDLINE, Google Scholar, BanglaJOL, Cochrane library). Various combinations of the following keywords were used: ‘prf’, ‘prf membrane’, ‘periodontal regenerative surgery’, ‘prf in dentistry’, ‘systemic diseases and periodontitis’, ‘drawback of prf’, ‘platelet-derived growth factors’, ‘prf in oms’, ‘prf in orthodontics’. Articles were searched until August 2021 All of these studies reveal that the PRF membrane enhances the healing of various defects in a variety of periodontal diseases and in several fields of dentistry. Studies are going on pulp regeneration and socket healing after extraction with PRF in dentistry. More emphasis should have to give to the prevention of periodontal diseases as well as more concern should have to give on PRF with flap surgery to enhance healing and improve the social health of the general population by preventing tooth loss and for different research purposes on PRF in different other fields of dentistry in Bangladesh. Update Dent. Coll. j: 2021; 11(2): 43-51

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“…Considerado como biomateriales autólogos (Choukroun et al 2001). Representan una generación más reciente de concentrados de plaquetas 44,46 . (Fig.…”

Section: Fibrina Rica En Plaquetas Avanzadas (A-prf)unclassified

“…Comparación de dos técnicas quirúrgicas en el tratamiento de múltiples recesiones gingivales intercaladas con una combinación de A-PRF y L-PRF. Tomado de Sameera S. 46 Se obtiene a través de un nuevo protocolo donde se han modificado los procedimientos de centrifugación para mejorar aún más la regeneración de tejidos. Mientras que la FRP estándar se centrifuga a 2700 rpm durante 12 min, la A-PRF se centrifuga a velocidades más bajas (1500 rpm, 14 min).…”

Section: Fibrina Rica En Plaquetas Avanzadas (A-prf)unclassified

Nuevas tendencias de andamios en los procedimientos regenerativos endodónticos. Revisión bibliográfica

Pérez

Carolina

2021

OdousUC

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La regeneración endodóntica (RE) se basa en el concepto de ingeniería tisular para restaurar el sistema de conductos a un estado saludable, buscando el desarrollo radicular continuo y del tejido circundante, e involucra componentes que incluyen células madre, factores de crecimiento y andamiajes, siendo estos últimos un elemento importante, sumamente estudiado. Definido como el soporte, vehículo de entrega o la combinación de materiales y biomoléculas con tecnología avanzada que facilitan la migración, unión y transporte celular. Exhibiendo beneficios como la estimulación para la producción de colágeno, diferenciación, proliferación y migración celular, angiogénesis, propiedades antibacterianas y antiinflamatorias. La presente investigación documental de diseño bibliográfico tuvo como objetivo analizar las nuevas tendencias de andamios dentro de los procedimientos regenerativos endodónticos (PRE), a través de la descripción del papel que juegan los diferentes componentes de la triada, enumerando, y explicando los beneficios de los diferentes andamios, y definiendo el de mayor ventaja. Basado en la revisión de artículos de revistas científicas indexadas, a través de la búsqueda electrónica en PubMed, ScienceDirect, Medline, Scielo y Google Académico; se consideró que la vascularización inadecuada, infección, procedimientos engorrosos, degradabilidad incierta, baja estabilidad, rigidez y resistencia representan un desafío importante. Conclusión: los concentrados plaquetarios de segunda generación, más recientes y optimizados (L-PRF y A-PRF) son las matrices que liberan mayor cantidad de plaquetas y factores de crecimiento, son de fácil preparación, presentan un mejor comportamiento del linaje fagocítico, disminuyen edema y dolor postoperatorio, aportando mejores resultados dentro de los PRE.

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Comparison of two surgical techniques in the treatment of multiple gingival recessions sandwiched with a combination of A-PRF and L-PRF

Cited by 15 publications

References 22 publications

Preparation and effect of lyophilized platelet-rich fibrin on the osteogenic potential of bone marrow mesenchymal stem cells in vitro and in vivo

Preparation and effect of lyophilized platelet-rich fibrin on the osteogenic potential of bone marrow mesenchymal stem cells in vitro and in vivo

Platelet-rich fibrin to manage different periodontal defects combine with Flap surgery and other uses in dentistry. A descriptive review

Nuevas tendencias de andamios en los procedimientos regenerativos endodónticos. Revisión bibliográfica

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