Comparison of two low-calorie diets: A prospective study of effectiveness and safety

Moreno, Óscar; Meoro, Amparo; Martínez, Agustín; Rodríguez, Carmen; Pardo, Carlos A.; Aznar, Silvia; López, Pilar; Serrano, Joaquín; Boix, E.; Martin, M. D.; Alfonso, Antonio Miguel Picó

doi:10.1007/bf03344163

Cited by 10 publications

(13 citation statements)

References 34 publications

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“…This, together with the absence of any significant adverse events or dropouts, confirms the acceptability and effectiveness of this intervention. Lowenergy (800-1000 kcal per day) diets are safe and effective in improving insulin resistance and other cardiovascular risk factors in obese patients, with 22 or without 23 diabetes. At baseline, the mean plasma glucose and lipid levels in the nondiabetic men were within the normal range, and accordingly, it is not surprising that no significant changes occurred in response to weight loss.…”

Section: Discussionmentioning

confidence: 99%

“…Moreover, this dietary approach is not suitable in the elderly, and is recommended for shortterm use. 22,23 However, improvements in sexual and urinary function with diet intervention alone are significant, and rapid weight loss has been shown to facilitate compliance with lifestyle-modification programs and improve engagement of obese men with health-care providers. 34 Recognition of sexual dysfunction may be a powerful motivator for lifestyle change in middle-aged and older men.…”

Section: Discussionmentioning

confidence: 99%

“…The International Prostate Symptom Scale (IPSS) is a series of questions used to assess the severity of irritative (frequency, urgency, nocturia) and obstructive LUTSs (incomplete emptying, intermittency, weak stream, straining), attributable to bladder outlet obstruction caused by prostatic enlargement. 19 Symptoms are classified as mild (score 0-7), moderate (8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19) or severe (20)(21)(22)(23)(24)(25)(26)(27)(28)(29)(30)(31)(32)(33)(34)(35).…”

Section: Questionnairesmentioning

confidence: 99%

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Effects of a low-energy diet on sexual function and lower urinary tract symptoms in obese men

et al. 2010

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Objective: Abdominal obesity and type 2 diabetes mellitus are associated with erectile and urinary dysfunction in men. The extent to which sexual function and lower urinary tract symptoms (LUTSs) are improved by weight loss remains unclear. Subjects: We compared the effects of 8 weeks of a low-calorie diet using meal replacements (Kicstart) on insulin sensitivity, plasma testosterone levels, erectile function (measured by the five-item version of the International Index of Erectile Function, IIEF-5), sexual desire (measured by the Sexual Desire Inventory, SDI) and LUTS (measured by the International Prostate Symptom Score, IPSS), in abdominally obese (body mass index X30 kg m À2 , waist circumference (WC) X102 cm) men (mean age 49.7 years) with uncomplicated diet or oral hypoglycemic-treated type 2 diabetes mellitus (n ¼ 19) or without type 2 diabetes mellitus (n ¼ 25), with a control group of nondiabetic men (n ¼ 26) with similar body mass index and WC. Results: Weight loss of B10% was significantly associated with increased insulin sensitivity, plasma testosterone levels, IIEF-5 and SDI scores, as well as reduced WC and IPSS scores, in diabetic as well as nondiabetic men. The degree of weight loss was significantly associated with improvements in plasma testosterone levels (r ¼ À0.34), erectile function (r ¼ À0.26) and LUTS (r ¼ 0.65). Reduction in LUTS was significantly associated with increased plasma testosterone (r ¼ À0.35), erectile function (r ¼ À0.42) and sexual desire (r ¼ À0.40). Conclusions: Diet-induced weight loss significantly and rapidly improves sexual function, and reduces LUTS, in obese middleaged men with or without diabetes.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Questionnairesmentioning

confidence: 99%

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Effects of a low-energy diet on sexual function and lower urinary tract symptoms in obese men

et al. 2010

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“…Several studies have looked at changes in plasma or serum proteins, such as albumin, prealbumin, retinol-binding protein and transferrin, as indirect markers of protein-energy malnutrition (Lewis et al, 1977;Shetty et al, 1979;Bogardus et al, 1981;Hoffer et al, 1984b;Pasquali et al, 1987;Hendler and Bonde, 1988;Ohno et al, 1989;Scalfi et al, 1990;Vazquez and Adibi, 1992;Vazquez et al, 1995;Moreno et al, 2006). However, plasma/serum proteins are affected by factors other than nutritional status, such as inflammation, infection and liver or kidney disease.…”

Section: Evidence Used In the Preparation Of The Opinionmentioning

confidence: 99%

“…Even though, on a theoretical basis, greater weight loss could be expected with a more pronounced caloric restriction, studies which compared VLCDs providing around 1 674 kJ (400 kcal) per day with VLCDs of around 3 347 kJ (800 kcal) per day generally did not show any additional benefit in terms of weight loss of energy intakes below 3 347 kJ (800 kcal) per day (Davies et al, 1989;Foster et al, 1992;Rössner and Flaten, 1997;Moreno et al, 2006;Lin et al, 2009). …”

Section: Introductionmentioning

confidence: 98%

Scientific Opinion on the essential composition of total diet replacements for weight control

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2015

EFSA Journal

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Following a request from the European Commission, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver a scientific opinion on the essential composition of total diet replacements for weight control. Total diet replacements for weight control are intended to induce a substantial energy deficit in overweight or obese adults who wish to lose weight and replace the whole diet in the context of energyrestricted diets for weight reduction. In this opinion, the Panel proposed a minimum protein content based on a Population Reference Intake for protein adjusted for the overweight or obese (75 g/day), a minimum carbohydrate content based on the obligatory glucose demands of the brain (30 g/day) and minimum contents of linoleic acid (11 g/day), α-linolenic acid (1.4 g/day) and micronutrients based on reference values established either by the Panel or by other scientific or authoritative bodies. Derived from the minimum content of macronutrients, the Panel proposed a minimum energy content of total diet replacements for weight control of 2 510 kJ/day (600 kcal/day). The Panel also advised on potential conditions and restrictions of use for these products. © European SUMMARYFollowing a request from the European Commission, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver a scientific opinion on the essential composition of total diet replacements for weight control. Total diet replacements for weight control are intended to induce a substantial energy deficit in overweight or obese adults who wish to lose weight and replace the whole diet in the context of energy-restricted diets for weight reduction.The guiding principle for providing advice on the essential composition of total diet replacements for weight control should be that products are safe and suitable when consumed as a sole source of nutrition for several weeks to months by overweight or obese adults in the context of energy-restricted diets for weight reduction. In order to avoid nutrient deficiencies, these products should, therefore, provide at least the Population Reference Intake or the Adequate Intake for adults of all indispensable nutrients. As Dietary Reference Values are generally established for healthy, normal-weight individuals, specific consideration has been given by the Panel in this opinion whether there was an increase in nutrient requirements in the overweight or obese or (rapid) weight loss leads to an increased nutrient loss and thus a higher requirement. The Panel also considered the extent to which different diet compositions impact on losses in fat-free mass, and on other adverse effects of weight loss diets, such as gallstone formation. The effectiveness of a product in terms of extent of weight loss was not in itself considered an appropriate determinant for the necessary composition of total diet replacements for weight control. ProteinThe Population Reference Intake of 0.83 g/kg body weight per day cannot be directly applied to overweight or obese indi...

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Cost-effectiveness and Budget Impact of Obesity Surgery in Patients with Type 2 Diabetes in Three European Countries(II)

et al. 2009

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Comparison of two low-calorie diets: A prospective study of effectiveness and safety

Abstract: The 3-month 800 kcal/day VLCD was more cost-effective and safer than the 1-month 458 kcal/day diet.

Cited by 10 publications

References 34 publications

Effects of a low-energy diet on sexual function and lower urinary tract symptoms in obese men

Effects of a low-energy diet on sexual function and lower urinary tract symptoms in obese men

Scientific Opinion on the essential composition of total diet replacements for weight control

Cost-effectiveness and Budget Impact of Obesity Surgery in Patients with Type 2 Diabetes in Three European Countries(II)

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