2008
DOI: 10.1183/09031936.00000208
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Comparison of two humidification systems for long-term noninvasive mechanical ventilation

Abstract: There is no consensus concerning the best system of humidification during longterm noninvasive mechanical ventilation (NIMV).In a technical pilot randomised crossover 12-month study, 16 patients with stable chronic hypercapnic respiratory failure received either heated humidification or heat and moisture exchanger. Compliance with long-term NIMV, airway symptoms, side-effects and number of severe acute pulmonary exacerbations requiring hospitalisation were recorded.Two patients died. Intention-to-treat statist… Show more

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Cited by 53 publications
(48 citation statements)
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“…NIV delivered via TFM has been proposed as an intervention to reverse ARF, and its use has been associated with better tolerance and comfort compared with an ONM. [33][34][35] These findings reinforce the importance of recommending the use of interfaces that generate less pressure against the face (ie, TFM or helmet) 36 for subjects who need prolonged NIV to prevent the development of SB, increasing the compliance and success of NIV. Furthermore, in patients who require prolonged intermittent mandatory ventilation, rotating the use of different types of masks may be another strategy for decreas- Hosmer-Lemeshow test ϭ chi-square ϭ 0.016.…”
Section: Discussionsupporting
confidence: 59%
“…NIV delivered via TFM has been proposed as an intervention to reverse ARF, and its use has been associated with better tolerance and comfort compared with an ONM. [33][34][35] These findings reinforce the importance of recommending the use of interfaces that generate less pressure against the face (ie, TFM or helmet) 36 for subjects who need prolonged NIV to prevent the development of SB, increasing the compliance and success of NIV. Furthermore, in patients who require prolonged intermittent mandatory ventilation, rotating the use of different types of masks may be another strategy for decreas- Hosmer-Lemeshow test ϭ chi-square ϭ 0.016.…”
Section: Discussionsupporting
confidence: 59%
“…Clinically, strategies to minimize skin damage include alternating interface types/ designs, using proper fit techniques, reducing mask tightness, and applying spacers on the forehead to reduce pressure on the nose. [36][37][38] Subjects with facial deformities were more difficult to fit, and subjects Յ2-y-old used a custom mask due to the unavailability of acceptable commercial devices. 18 Use of an oronasal mask was a significant risk factor for tissue injury among subjects Ͼ18 y old.…”
Section: Discussionmentioning
confidence: 99%
“…These leaks are extremely common in neuromuscular patients. 19,20 Therefore, although an HME and a heated humidifier showed similar tolerance and side effects during long-term MV, 21 we prefer a heated humidifier because of its greater efficacy in case of unintentional leak. [22][23][24] In addition, as compared to a heated humidifier, an HME increases the resistance of the circuit and the dead space, and therefore the work of breathing, during invasive MV.…”
Section: Evaluation Of the Patients' Equipment Versus The Prescribersmentioning
confidence: 99%
“…However, despite their advantage of a minimal facial contact, which widens the field of vision and allows the use of eyeglasses, few patients used nasal pillows. 17 Until recently, all nasal pillows available in France had intentional leak and therefore could be used only with bi-level ventilators, given that any modification of a medical device (eg, sealing a hole) was prohibited by French law. We encourage manufacturers to develop non-leak nasal pillows, which may be an alternative to mouthpiece MV during daytime.…”
Section: Evaluation Of the Patients' Equipment Versus The Prescribersmentioning
confidence: 99%