Comparison of two frailty identification tools for critically ill patients: A post-hoc analysis of a multicenter prospective cohort study

Taniguchi, Leandro Utino; Ibrahim, Quazi; Azevedo, Luciano César Pontes; Stelfox, Henry T.; Bagshaw, Sean M.

doi:10.1016/j.jcrc.2020.06.007

Cited by 16 publications

(15 citation statements)

References 20 publications

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“…We determined frailty using the Clinical Frailty Scale (CFS) [ 17 , 18 ] at the time of ICU admission, based on the patient's level of physical function in the month preceding admission [ 19 ]. The highest level of mobility during ICU stay was determined using the ICU mobility scale [ 20 ].…”

Section: Methodsmentioning

confidence: 99%

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The impact of COVID-19 critical illness on new disability, functional outcomes and return to work at 6 months: a prospective cohort study

et al. 2021

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Background There are few reports of new functional impairment following critical illness from COVID-19. We aimed to describe the incidence of death or new disability, functional impairment and changes in health-related quality of life of patients after COVID-19 critical illness at 6 months. Methods In a nationally representative, multicenter, prospective cohort study of COVID-19 critical illness, we determined the prevalence of death or new disability at 6 months, the primary outcome. We measured mortality, new disability and return to work with changes in the World Health Organization Disability Assessment Schedule 2.0 12L (WHODAS) and health status with the EQ5D-5LTM. Results Of 274 eligible patients, 212 were enrolled from 30 hospitals. The median age was 61 (51–70) years, and 124 (58.5%) patients were male. At 6 months, 43/160 (26.9%) patients died and 42/108 (38.9%) responding survivors reported new disability. Compared to pre-illness, the WHODAS percentage score worsened (mean difference (MD), 10.40% [95% CI 7.06–13.77]; p < 0.001). Thirteen (11.4%) survivors had not returned to work due to poor health. There was a decrease in the EQ-5D-5LTM utility score (MD, − 0.19 [− 0.28 to − 0.10]; p < 0.001). At 6 months, 82 of 115 (71.3%) patients reported persistent symptoms. The independent predictors of death or new disability were higher severity of illness and increased frailty. Conclusions At six months after COVID-19 critical illness, death and new disability was substantial. Over a third of survivors had new disability, which was widespread across all areas of functioning. Clinical trial registrationNCT04401254 May 26, 2020.

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Section: Methodsmentioning

confidence: 99%

“…18 Department of Physiotherapy, Monash Health, Melbourne, Victoria, Australia. 19 Physiotherapy Department, St Vincent's Hospital, Melbourne, Victoria, Australia. 20 Canberra Health Services, Canberra, Australia.…”

Section: Supplementary Informationmentioning

confidence: 99%

The impact of COVID-19 critical illness on new disability, functional outcomes and return to work at 6 months: a prospective cohort study

et al. 2021

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“…There is good evidence that frailty measures rely heavily on pre-existing comorbidities for frailty classification, for instance, modified frailty index. 52 However, this systematic review demonstrated that phenotype frailty measurements were utilised more in the surgical patients admitted to ICU.…”

Section: Discussionmentioning

confidence: 94%

Association between frailty and clinical outcomes in surgical patients admitted to intensive care units: a systematic review and meta-analysis

Chan

Ueno

Afroz

et al. 2022

British Journal of Anaesthesia

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“…Another popular score is based on the frailty index originally suggested by Rockwood that has been condensed from the original 70 clinical deficit assessments to more simple versions using only 19 15 or 11 and lately only five items, 16 all titled modified frailty index (mFI). By reducing the original list in this way, mainly using diagnostic codes, there is a risk that information about frailty components gets lost.…”

Section: Frailty—methods To Identify Frail Patientsmentioning

confidence: 99%

Frailty and its implication for anaesthesiologists

Beil

2021

Acta Anaesthesiol Scand

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Comparison of two frailty identification tools for critically ill patients: A post-hoc analysis of a multicenter prospective cohort study

Cited by 16 publications

References 20 publications

The impact of COVID-19 critical illness on new disability, functional outcomes and return to work at 6 months: a prospective cohort study

The impact of COVID-19 critical illness on new disability, functional outcomes and return to work at 6 months: a prospective cohort study

Association between frailty and clinical outcomes in surgical patients admitted to intensive care units: a systematic review and meta-analysis

Frailty and its implication for anaesthesiologists

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