Comparison of two different orthokeratology lenses and defocus incorporated soft contact (DISC) lens in controlling myopia progression

Abstract

Background To compare axial elongation in 8–11-year-old myopes wearing orthokeratology (OK) lenses with different back optic zone diameters (BOZD), defocus incorporated soft contact (DISC) lenses, and single-vision soft contact lenses (SCLs). Methods A total of 122 children (aged 8–11 years) with spherical equivalent refraction (SER) between − 1.00 D and − 4.00 D were enrolled in this prospective study and randomly assigned to four groups: 5.0 mm-BOZD OK, 6.2 mm-BOZD OK, DISC, and single-vision SCLs. Children in each group were further divided into subgroups stratified by the average baseline SER: low myopic eyes (SER: − 1.00 D to − 2.50 D) and moderate myopic eyes (SER: − 2.50 D and over). Axial length (AL) was measured at baseline and after one year. Results The 5.0 mm-BOZD OK, 6.2 mm-BOZD OK, and DISC groups exhibited significantly slower AL elongation than the SCL group. The proportion of slow progressors (AL elongation ≤ 0.18 mm/year) in the first three groups was 42%, 23%, and 29%, respectively. Furthermore, one-year AL elongation was significantly smaller in the 5.0 mm-BOZD OK group compared with the 6.2 mm-BOZD OK group. Regardless of SER, children in the 5.0 mm-BOZD OK and DISC groups showed comparably slower AL elongation than those in the SCL group. However, fitting with 6.2 mm-BOZD OK lenses significantly retarded AL elongation in moderate myopic eyes, but not in low myopic eyes. Conclusions Overall, 5.0 mm-BOZD OK lenses, 6.2 mm-BOZD OK lenses, and DISC lenses were effective in retarding AL elongation in 8–11-year-old myopes compared with single-vision SCLs, but for children with SER less than − 2.50 D, fitting with 5.0 mm-BOZD OK lenses and DISC lenses yielded better myopia control efficacy compared to wearing single-vision SCLs or 6.2 mm-BOZD OK lenses.

Slowing myopia progression in children

“…Defocus incorporated soft contact lenses are novel bifocal contact lenses with a concentric ring pattern that reduces peripheral and central defocus and optimizes retinal image quality for points on and in front of the retina. This slows eye growth when compared with the effect of conventional contact lenses, while clear vision is maintained through the center [62,63]. They significantly improved the vision-related quality of life of Chinese children aged 7 to 12 years with myopia ≤ -4.00 D and astigmatism < 1.50 D compared with single-vision spectacles, and they elicited greater patient satisfaction than single-vision spectacles [64].…”