Comparison of Tumor Markers and Risk of Malignancy Index (RMI) in Borderline OvarianTumors Names of

Abstract

Background Borderline ovarian tumours (BOTs) are non-invasive tumours with low malignancy potential frequently observed in patients of reproductive age. Therefore, preoperative differential diagnosis is important in these patients. In our study, we tried to differentiate benign and borderline ovarian tumours preoperatively using risk of malignancy (RMI) index and tumour markers. Methods In our study, we retrospectively compared tumour markers and risk of malignancy index (RMI) of 85 patients aged between 17–84 years with postoperative benign (n:52) and borderline (n:33) ovarian cysts. Results In our study, the mean age of the benign group was significantly higher than the borderline group (p = 0.001). Ca 125 and RMI values were significantly higher in the borderline group compared to the benign group (p = 0.001 and p = 0.018). In addition, mucinous tumours had significantly larger tumour diameter than serous tumours in the borderline group (p = 0.022). Conclusion As a result of our study, since borderline ovarian tumours are seen in young patients of reproductive age, it may be suggested to use Ca125 and RMI for the differential diagnosis of benign and borderline cysts preoperatively.