As we go to the press today, on February 28, over 28 million people have tested positive for the COVID-19 virus in the U.S and over 512,000 have died. The COVID -19 collection of the JVS journals continues to grow and includes now more than 120 publications on COVID-19 and vascular disease.I am pleased to introduce the 2021 May issue of the Journal of Vascular Surgery and highlight four excellent papers, which are freely available for the next 2 months. Our Editors' Choice article for this issue is "Validation of the Global Limb Anatomic Staging System in first-time lower extremity revascularization," by Dr Liang and colleagues from Boston, Massachusetts. 1 This is a retrospective review of 1060 patients who had undergone 1180 first-time open or endovascular revascularizations for chronic limb threatening ischemia. Using the angiographic images, the limbs were classified according to the GLASS grading, published in the Global Vascular Guidelines. The grades from 0 to 4 are based on the length of the disease, the presence, length, and location of chronic total occlusion (CTO), and the extent of popliteal artery involvement in patients with femoropopliteal disease and according to the lengths and locations of the stenosis and of the CTO in patients with infrapopliteal disease. The main finding in this paper is that a higher GLASS stage was associated with greater rates of reintervention and restenosis and the take home message is that GLASS can be used to predict reintervention and restenosis after first-time lower extremity revascularization.Our CME article this month is titled "Comparison of open-and closed-cell stent design outcomes after carotid artery stenting in the Vascular Quality Initiative." 2 It was written by Dr Faateh and colleagues from Baltimore, Maryland and La Jolla, California. In this VQI study, carotid stenting with a distal protection device was performed using closed-cell stents in 1384 and open-cell stents in 1287 patients. There was no significant difference between the two groups in in-hospital mortality, stroke, and stroke/death. Patients who received closed cell stents, however, had increased odds of in-hospital and 1-year stroke and death rate when stenting was used for lesions located in the carotid bifurcation and not just in the internal carotid artery. This might be related to the relatively lower conformability of closed-cell stents in a tortuous bifurcation anatomy.The next article is a multicenter study, written by Dr Jonathan Bath and colleagues, and is entitled "Endovascular interventions for claudication do not meet minimum standards for the Society for Vascular Surgery efficacy guidelines." 3 This VQI study investigated outcomes of endovascular treatment for intermittent claudication in 16,152 patients and compare them to standards established in the SVS guidelines. The main finding of the study was that only 32% the patients were free of recurrent claudication at 2 years. Recurrence was more likely with treatment of more than two arteries or in those who had atherectomy. The ...