Comparison of transaxial resolution in 180° and 360° SPECT with a rotating scintillation camera

Bice, Alden N.; Clausen, M.; Loncaric, S.; Wagner, Henry N.

doi:10.1007/bf00252638

Cited by 11 publications

(2 citation statements)

References 12 publications

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“…However, they were generated from the same sets of shortaxis images, and therefore have common background characteristics. Although we admit significant differences in regional counts among genders and camera rotation ranges [10][11][12][13][14][15], the institutional differences in the Japanese population seemed to be less critical if these factors were in agreement.…”

Section: Discussionmentioning

confidence: 99%

The validity of multi-center common normal database for identifying myocardial ischemia: Japanese Society of Nuclear Medicine working group database

et al. 2009

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Purpose. The Japanese Society of Nuclear Medicine (JSNM) working group has created a myocardial perfusion imaging database applicable to standard acquisition protocol. The aim of this study is to validate the diagnostic accuracy of the common normal database compared with the expert interpretation of each institute. Methods. Five institutions participated in this study and used different acquisition settings which included 360°/180° rotation, camera configuration and camera orbits. The software and its version used in each institution also varied. The working group database was applied to detect the culprit coronary territory from a total of 166 patients with coronary artery disease (CAD) and 145 patients with low-likelihood of CAD. Results. When summed stress score ≥4 was defined as significant abnormality, overall sensitivity, specificity and accuracy of patient-based analysis were 77%, 72% and 75%, respectively, based on quantitative analysis using the common database, whereas those by institutional visual expert reading were 72%, 79% and 75%, respectively. Conclusion. The common database, which was created by a multi-center working group and separated between male/female with 180/360° acquisitions, demonstrated comparable diagnostic accuracy to expert interpretation by each institute, and it may be applicable to multi-center studies.

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Section: Discussionmentioning

confidence: 99%

The validity of multi-center common normal database for identifying myocardial ischemia: Japanese Society of Nuclear Medicine working group database

et al. 2009

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“…Go et al (9) described a rate of 36% false-positive defects in myocardial slices with 180° sampling. Most recently, Bice et al (2) found enhanced oval distortion of circular objects in SPECT reconstructions, if the object was situated off axis and imaged with 180° rotation. Despite these findings, the majority of workers employ this limited-angle sampling technique.…”

Section: Disciissionmentioning

confidence: 99%

Quantitative Evaluation of Myocardial Stress/Rest 201TISPECT: Results of a ROI-Based Method in 108 Patients with CHD

Buell¹,

Stirner²,

Dahl³

et al. 1987

Nuklearmedizin

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ROI-based polar maps (33 ROIs) were employed to evaluate quantitatively stress/rest myocardial 201TI SPECT in 108 patients with angiographically proven coronary heart disease (CHD) in comparison with 30 controls. Sensitivity in detecting a CHD with stenoses of > 50% of luminal diameter was determined versus normal regional values (± 2.5 SD) employing vitality (VI) and wash-out corrected redistribution (RD). The method was evaluated referring to the severity of the disease, to the number of ROIs displaying changes [(a) 1 ROI, (b) >2 ROIs], to validity of VI, RD or a combination thereof, and for specificity. Wash-out values were found to depend on degree of stress individually achieved and thus were not used as a threshold criterion. Sensitivity in supply areas with old myocardial infarctions was 95% (a) and 86% (b), resp. With no infarction, it was 96% (a) and 79% (b), resp. VI in stenosis > 75% was more sensitive than RD. However, combined evaluation of VI and RD yielded sensitivities from 91-100% (a) and 77-94% (b), resp. for different main supply areas. In stenosis < 50% with normal VI, RD was positive in 18-31 %. Specificity turned out to be 91 % (a) and 97% (b), resp. We conclude that the method presented is reliable to quantify numerically 201TI kinetics in myocardial SPECT, aimed at detecting and describing CHD.

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Regional myocardial wall thickening and global ejection fraction in patients with low angiographic left ventricular ejection fraction assessed by visual and quantitative resting ECG-gated 99m Tc-tetrofosmin single-photon emission tomography and magnetic resonance imaging

Stollfuß

Haas

Matsunari

et al. 1998

European Journal of Nuclear Medicine and Molecular Imaging

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We investigated the use of visual and quantitative technetium 99m tetrofosmin ECG-gated single-photon emission tomography (SPET) for the assessment of regional myocardial wall thickening (WT) and left ventricular (LV) ejection fraction (EF) in comparison with gated magnetic resonance imaging (MRI) in patients with a low angiographic LVEF. Gated SPET using 99mTc-labelled flow tracers offers potential for simultaneous assessment of myocardial perfusion and LV function. Few data are available on the use of visual and quantitative gated SPET in patients with low LVEF. In this study 21 patients with low angiographic LVEF (mean 37%+/-5%) were studied. Resting gated 99mTc-tetrofosmin SPET and gated MRI were performed within 48 h. WT was assessed by visual interpretation (five point score) and quantitative analysis based on count increase. There was good agreement for EF measurements by MRI and gated SPET (mean EF: 33%+/-12% vs 35%+/-11%, r = 0.86, P<0.001). Areas under receiver operator characteristic curves (AUC) for differentiation between MRI WT score points ranged from 0.60 to 0.66 for visual SPET WT analysis, from 0.59 to 0.71 for delta count increase values and from 0.46 to 0.60 for % WT, indicating substantial overlap between WT categories. Absolute agreement for visual WT between MRI and gated SPET ranged from 25% to 57% (kappa 0.03-0.25) depending on tracer uptake, and was limited in areas with moderate to severe perfusion defects (kappa 0.03-0.13). It is concluded that gated SPET provided reliable estimates of regional WT and global function in patients with low angiographic LVEF.

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Comparison of transaxial resolution in 180° and 360° SPECT with a rotating scintillation camera

Cited by 11 publications

References 12 publications

The validity of multi-center common normal database for identifying myocardial ischemia: Japanese Society of Nuclear Medicine working group database

The validity of multi-center common normal database for identifying myocardial ischemia: Japanese Society of Nuclear Medicine working group database

Quantitative Evaluation of Myocardial Stress/Rest 201TISPECT: Results of a ROI-Based Method in 108 Patients with CHD

Regional myocardial wall thickening and global ejection fraction in patients with low angiographic left ventricular ejection fraction assessed by visual and quantitative resting ECG-gated 99m Tc-tetrofosmin single-photon emission tomography and magnetic resonance imaging

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