Comparison of trans-anal endoscopic operation and trans-anal excision of rectal tumors

Abstract

BackgroundTrans-anal endoscopic operation (TEO) has developed to facilitate proper tumor location and ensure excision safely.MethodsWe reviewed 92 patients enrolled in our database between 2006 and 2014 who were diagnosed with early rectal tumors and who underwent conventional trans-anal excision (TAE) or TEO. Clinical data were collected prospectively to compare safety and feasibility between two techniques.ResultsNinety-two patients underwent trans-anal local excision for lower rectal tumors. TEO and TAE were performed in 48 and 44 patients, respectively. Age, sex, and comorbidities were similar. There was no significant difference in tumor diameter (1.6 ± 1.68 cm vs. 1.17 ± 1.17, respectively). Tumor height, however, was higher in the TEO (7.46 ± 3 cm) than the TAE group (3.84 ± 1.88 cm, p < 0.001). Four complications, perianal abscess, and two perforations, occurred in the TEO group, whereas no major complications occurred in the TAE. Seven patients (14.6%) underwent TEO underwent a salvage operation compared to only a single patient in TAE group (2.3%, p = 0.039). Eight patients (17.4%) diagnosed with adenocarcinoma developed recurrence, four in each group. Disease-free survival was similar between groups (TEO – 41.8 months, 95% RI 39.4–44.1; TAE 79.7 months, 95% RI 72.2–87.3). However, more TAE patients (n = 7, 15.9%) than TEO patients (n = 2, 4.2%) underwent chemotherapy.ConclusionsTEO treatment of local rectal tumors is safe and feasible and can achieve an adequate resection margin. Local recurrence was similar in both groups. However, the numbers of salvage operations and minor complications were higher in the TEO group.

Management of early rectal cancer; current surgical options and future direction

“…Owing to the similarities of TEM and TEO it may be assumed that both will be able to offer similar results. There are also a growing number of studies which demonstrate comparable outcomes to TEM in both TEO[ 26 , 29 , 36 ] and TAMIS platforms[ 32 , 37 , 38 ]. Table 1 provides a brief comparison of the suggested merits of each technique.…”