Comparison of tobacco and alcohol consumption in young and older patients with oral squamous cell carcinoma: a systematic review and meta-analysis

Batistella, Elis Ângela; Gondak, Rogério; Rivero, Elena Riet Correa; Warnakulasuriya, Saman; Guerra, Eliete Neves Silva; Porporatti, André Luís; Canto, Graziela De Luca

doi:10.1007/s00784-022-04719-z

Cited by 9 publications

(1 citation statement)

References 58 publications

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“…Oral carcinoma accounts for approximately 30% of all head and neck cancers, and more than 90% of them are OSCC [1][2][3]. More younger people are being diagnosed with OSCC [4,5]. At present, the clinical treatment of OSCC is still based on surgical treatment and adjuvant chemoradiotherapy [6][7][8][9].…”

Section: Introductionmentioning

confidence: 99%

Effect of acute normovolemic hemodilution on long-term prognosis of patients with oral squamous cell carcinoma undergoing flap reconstruction: a retrospective study

Chen

Shi

et al. 2023

Preprint

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Objective To investigate the effect of acute normovolemic hemodilution on long-term prognosis of oral squamous cell carcinoma (OSCC) patients after tumor resection and flap reconstruction. Methods This study retrospectively analyzed follow-up data for 371 OSCC patients who underwent tumor resection and flap reconstruction for the first time at our hospital from January 1, 2015, to December 31, 2020. The patients were split into three groups: no blood transfusion (NBT), acute normovolemic hemodilution (ANH), and allogeneic blood transfusion (ABT). Measurement data were analyzed by ANOVA and enumeration data by χ2 tests. Survival analysis with the Cox model was used to confirm independent prognostic factors. Disease-free (DFS) and overall (OS) survival were calculated by the life table method and K-M curve. Results The ANH group had a 0.523-fold higher risk of recurrence than the NBT group (P = 0.010). The ABT group had a 1.844-fold higher risk of death than the NBT group (P = 0.033). Among those with lymph node metastasis, the ANH group had a lower risk of recurrence, 0.436 times higher than the NBT group (P = 0.017), and the ABT group had a higher risk of death, 2.186 times higher than the NBT group (P = 0.032). Conclusion ANH can reduce immune system suppression by decreasing the amount of allogeneic blood to reduce tumor recurrence and risk of tumor-specific death, and this result is more prominent in OSCC patients with lymph node metastasis. Clinical relevance Preoperative ANH can effectively reduce the recurrence rate of patients with OSCC.

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Section: Introductionmentioning

confidence: 99%

Effect of acute normovolemic hemodilution on long-term prognosis of patients with oral squamous cell carcinoma undergoing flap reconstruction: a retrospective study

Chen

Shi

et al. 2023

Preprint

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The impact of electronic and conventional cigarettes on periodontal health—a systematic review and meta-analysis

Thiem,

Donkiewicz,

Rejaey

et al. 2023

Clin Oral Invest

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Objectives This systematic review and meta-analysis examined the effects of electronic cigarettes on periodontal health compared to conventional cigarette smoke and a non-smoking population. Materials and methods MEDLINE, Embase, Web of Science, CENTRAL, and ClinicalTrials.gov were screened for literature. Eligibility criteria included clinical studies published between 2006 and 2022 that compare e-cigarettes and conventional cigarettes on periodontal health (bleeding on probing (BoP), plaque index (PI), probing depth (PD), attachment loss (AL), marginal bone loss (MBL), tooth loss, molecular inflammation markers, salivary flow rate). Meta-regression analysis was used to examine the influence of moderator variables. Results Sixteen studies were found to be eligible for qualitative synthesis. Individual analyses showed that cigarette smokers had significantly higher PI, PD, AL, and MBL and increased concentrations of proinflammatory mediators than e-cigarette users and non-smokers. Meta-analysis revealed a 0.33-fold lower chance for BoP in e-cigarette users compared to smokers (p = 0.03), whereby meta-regression failed to detect any effects regarding the age of users and frequency of smoking. A 0.01-fold decreased chance for positive BoP in e-cigarette users compared with non-smokers was seen (p < 0.01). Conclusions The current findings suggest that that e-cigarette use might be considered a healthier alternative to cigarette smoking concerning periodontal health. Even so, harmful effects of electronic nicotine delivery system (ENDS) usage on periodontal health were seen as well. However, a definitive decision on this research question remains elusive due to the absence of randomized controlled trials. Clinical relevance Electronic cigarettes, marketed as a safer alternative to traditional cigarettes, are becoming increasingly popular. Evidence on the use of electronic cigarettes as a cessation aid and its beneficial impact compared to cigarette smoke remains inconclusive, so the analysis conducted in this review addresses a recent question of high clinical relevance.

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Prevalence of locoregional recurrence and survival post-treatment of head and neck cancers in Africa: a systematic review and meta-analysis

Melariri¹,

Els²,

Oyedele³

et al. 2023

eClinicalMedicine

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Comparison of tobacco and alcohol consumption in young and older patients with oral squamous cell carcinoma: a systematic review and meta-analysis

Cited by 9 publications

References 58 publications

Effect of acute normovolemic hemodilution on long-term prognosis of patients with oral squamous cell carcinoma undergoing flap reconstruction: a retrospective study

Effect of acute normovolemic hemodilution on long-term prognosis of patients with oral squamous cell carcinoma undergoing flap reconstruction: a retrospective study

The impact of electronic and conventional cigarettes on periodontal health—a systematic review and meta-analysis

Prevalence of locoregional recurrence and survival post-treatment of head and neck cancers in Africa: a systematic review and meta-analysis

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