Comparison of three types of treatment modalities on the outcome of fingertip injuries

Berg, Wiebren B. van den; Vergeer, Rob A; Sluis, Corry K. van der; Duis, Henk-Jan ten; Werker, Paul M. N.

doi:10.1097/ta.0b013e318248bc8c

Cited by 39 publications

(33 citation statements)

References 22 publications

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“…The main residual deformity with secondary healing is the hook nail or parrot beak deformity, which occurs mainly in the most proximal injuries [1,31]. This can be a problem for some patients, but in our experience, most patients only have minor functional problems with this.…”

Section: Aesthetic Results Of Secondary Healingmentioning

confidence: 90%

“…Residual nail deformity was the usual cause of aesthetic dissatisfaction. In the total population of 1,592 fingertip amputations of our review, there were 100 reported nail deformities, (6 % of the fingertip injuries) [1,3,5,6,13,15,23,28,31].…”

Section: Aesthetic Results Of Secondary Healingmentioning

confidence: 99%

“…The highest reported incidence of cold intolerance was 86 % at 2 months [31], but all reports showed a decreasing incidence with time. Cold intolerance frequently resolved by 1 year and caused disability in only a small minority of patients [24].…”

Section: Cold Intolerancementioning

confidence: 99%

“…Although neuroma-type problems can occur with secondary healing, they are rare [15,31]. On the other hand Chow and Ho [6] reported a 7 % incidence of painful neuroma in 94 surgically treated patients (revision amputations, V-Y advancement flaps, and skin grafts).…”

Section: Studies Comparing Surgery To Secondary Healingmentioning

confidence: 99%

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Secondary Healing of Fingertip Amputations: A Review

Krauss

Lalonde

2014

Hand (New York, N,Y.)

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Section: Aesthetic Results Of Secondary Healingmentioning

confidence: 90%

Section: Aesthetic Results Of Secondary Healingmentioning

confidence: 99%

Section: Cold Intolerancementioning

confidence: 99%

Section: Studies Comparing Surgery To Secondary Healingmentioning

confidence: 99%

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Secondary Healing of Fingertip Amputations: A Review

Krauss

Lalonde

2014

Hand (New York, N,Y.)

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“…For example, clinicians may attempt to restore an aesthetic attribute or maintain gross manual dexterity. 21 As a result, depending on the type of amputation, clinicians may use skin flaps to cover the wound to minimize tissue necrosis, 22,23 replant the amputated tip, [24][25][26][27][28] or fit for a prosthetic device. 29 For certain cases in children, clinical intervention is often kept minimal with a focus on cleaning and dressing the wound.…”

Section: Clinical Cases Of Digit Regrowthmentioning

confidence: 99%

Looking Ahead to Engineering Epimorphic Regeneration of a Human Digit or Limb

Quijano

Lynch

Allan

et al. 2016

Tissue Engineering Part B: Reviews

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Approximately 2 million people have had limb amputations in the United States due to disease or injury, with more than 185,000 new amputations every year. The ability to promote epimorphic regeneration, or the regrowth of a biologically based digit or limb, would radically change the prognosis for amputees. This ambitious goal includes the regrowth of a large number of tissues that need to be properly assembled and patterned to create a fully functional structure. We have yet to even identify, let alone address, all the obstacles along the extended progression that limit epimorphic regeneration in humans. This review aims to present introductory fundamentals in epimorphic regeneration to facilitate design and conduct of research from a tissue engineering and regenerative medicine perspective. We describe the clinical scenario of human digit healing, featuring published reports of regenerative potential. We then broadly delineate the processes of epimorphic regeneration in nonmammalian systems and describe a few mammalian regeneration models. We give particular focus to the murine digit tip, which allows for comparative studies of regeneration-competent and regeneration-incompetent outcomes in the same animal. Finally, we describe a few forward-thinking opportunities for promoting epimorphic regeneration in humans.

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