Comparison of three techniques of esophagectomy within a residency training program

Putnam, Joe B.; Suell, Douglas M.; McMurtrey, Marion J.; Ryan, Michael; Walsh, Garrett L.; Natarajan, Giri; Roth, Jack A.

doi:10.1016/0003-4975(94)90990-3

Cited by 93 publications

(49 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Several investigators have made similar observations, with variation in the absolute number of positive nodes separating survivors from nonsurvivors. 5,16,17 In this report the presence of seven or more positive nodes, as previously suggested by Akiyama et al, 16 predicted the worst prognosis. However, despite the relative importance of the number of positive nodes, it is nearly impossible to predict with certainty who among node-positive patients will achieve long-term survival.…”

Section: Discussionsupporting

confidence: 64%

Should En Bloc Esophagectomy Be the Standard of Care for Esophageal Carcinoma?

2001

View full text Add to dashboard Cite

ObjectiveTo determine the impact of radical node dissection on the recurrence patterns and survival rates of patients with carcinoma of the esophagus. Summary Background DataThe role of esophagectomy with radical lymphadenectomy in the treatment of esophageal cancer is controversial. Most centers favor a limited operation with no attempt at nodal clearance. However, disease recurrence and patient survival rates remain dismal with or without preoperative therapy. The authors postulate that a more radical node dissection would reduce local failure rates and enhance survival. MethodsOne hundred eleven patients with esophageal cancer underwent en bloc esophagectomy with radical lymph node dissection between 1988 and 1998. In 90% of patients the procedure was applied nonselectively and without any preoperative therapy. Patients were prospectively followed up for recurrence patterns and survival. ResultsThe 5-year survival rate including noncancer deaths was 40%. The 5-year survival rates for patients with stage 1, 2A, 2B, 3, and 4 disease were 78%, 72%, 0%, 39%, and 27%, respectively. Forty percent of patients had node-negative disease (5-year survival rate, 75%), and 60% had nodal metastases (5-year survival rate, 26%). Recurrence occurred in 39% of patients and was local in only 8%. ConclusionsRadical esophagectomy results in superior overall and stagespecific 5-year survival rates. Extensive node dissection has a positive impact on survival rates, particularly in patients with nodal metastases.

show abstract

Section: Discussionsupporting

confidence: 64%

Should En Bloc Esophagectomy Be the Standard of Care for Esophageal Carcinoma?

2001

View full text Add to dashboard Cite

show abstract

“…In their prospective trial Goldminc et al [23] were unable to demonstrate any difference in the complication rate of transhiatal as compared to transthoracic resection. Similarly, the studies by Putnam et al [24] and by Horstmann et al [25] did not reveal any disadvantage of the transthoracic approach. However, patients in both groups were not completely comparable with a tendency to avoid thoracotomy in highrisk patients.…”

Section: Discussionmentioning

confidence: 68%

Limited Prognostic Value of Two-Field Lymphadenectomy in Surgery for Esophageal Carcinoma

Hiller¹,

Jähne²,

Piso³

et al. 1998

Oncol Res Treat

View full text Add to dashboard Cite

“…Ovarialkarzinom (2,6,8,9) Mammakarzinom (2,7,9) Uterustumoren (8) Prostatakrebs (9) Hodentumor (4) Kolontumoren (7,9) Leberkrebs (1,7) Hirntumoren (5) Leukämie (9) Malignes Melanom (3,7) Cefasel forte Der Partner in der Selentherapie…”

Section: Non-rcsective Treatment In Oesophageal Cancerunclassified

“…More than 50% of the patients with localized EC reveal T3 or T4 tumours at surgery, nearly all of them with lymph node metastases [4,10]. The special anatomic situation of the oeso phagus with its tough neighbourhood to critical structures is the reason that less than half of these locally advanced tumours have been completely resected.…”

Section: Locally Advanced Cancer (T3/4 N X Mo)mentioning

confidence: 99%

“…Perioperative mortality even in ex perienced centres was reported on 2-10% of the patients, depending on tumour stage, resection procedure and the expe rience of the surgeon. Moreover, anastomotic leakage with subsequent stenosis as well as functional disturbances (reflux or dumping) cause long-term complaints in 25-60% of the re sected patients [3][4][5]. All these issues have raised the question of whether multi modal nonoperative treatment may be possible in EC without impairing the chance for cure of the patients.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Possibilities of Non – Resective Treatment Procedures in Oesophageal Cancer

Stahl¹,

Wilke²

1996

Oncol Res Treat

View full text Add to dashboard Cite

Despite constant improvement in surgical techniques and peri-operative management over the past decades, still about 90% of the Western patients with oesophageal cancer (EC) will die from their disease. Additionally, surgery causes significant mortality and morbidity of the patients. These problems raised the interest in nonoperative, organ-preserving treatment procedures. Apart from metastatic disease, it is not clear from the literature, however, if a nonoperative therapy offers the patients a comparable chance of cure with less toxicity. Therefore, surgery is recommended in localized oesophageal cancer, so far. However, as the number of promising data on combined chemoradiotherapy, particularly in locally advanced tumours, increases, efforts get imperative to investigate the role of nonoperative therapies within randomized clinical trials.

show abstract

Comparison of three techniques of esophagectomy within a residency training program

Cited by 93 publications

References 12 publications

Should En Bloc Esophagectomy Be the Standard of Care for Esophageal Carcinoma?

Should En Bloc Esophagectomy Be the Standard of Care for Esophageal Carcinoma?

Limited Prognostic Value of Two-Field Lymphadenectomy in Surgery for Esophageal Carcinoma

Possibilities of Non – Resective Treatment Procedures in Oesophageal Cancer

Contact Info

Product

Resources

About