Comparison of three film analysis softwares using EBT2 and EBT3 films in radiotherapy

Abstract

Introduction The purpose of the study was to compare the results of gamma value based film analysis according to the used type of self-developer film and software product. Material and methods The films were irradiated with different treatment techniques such as 3D conformal and intensity modulated radiotherapy with static and rotational delivery. Stereotactic plans with conformal and intensity modulated arc techniques, using coplanar and non-coplanar beam setup were also evaluated. The data of irradiated film were compared with the planned planar dose distribution exported from the treatment planning system. Three film analysis software programs were evaluated: PTW Mephysto (PTW), FilmQA Pro (FQP) and radiohromic.com(RC). Both EBT2 and EBT3 types of films were examined. The comparisons of dose distributions were performed with gamma analysis using 10% cut-off level. Results The results of the gamma analysis for larger fields were between 78.3% and 98.3%, 75.7% and 100%, 80.2% and 98.8% with PTW, FQP and RC, respectively. The results of evaluation in case of stereotactic measurements were 76.8%–99.2% for PTW, 95.7%–100% for FQP and 91.2%–99.9% for RC. Conclusions All the three software programs are suitable for calibrating and evaluating films, performing gamma analysis, and can be used for patient specific quality assurance measurements. There is no direct connection between gamma passing rate and absolute accuracy or software quality, it is just a feature of the software. The interpretation of own results has to be defined on an institutional level according to given workflow and preliminary results.

Impact of transducer arrays on deep-site dosimetry in radiotherapy with concurrent TTFields for glioblastoma (extreme analysis)

“…Conventionally segmented mode is generally adopted for glioblastoma radiotherapy. Thus, taking the 3%/3 mm criteria as the standard to evaluate the consistency of the two dose distributions is generally accepted in clinical practice [22][23][24] . In other words, even when the number of wrapped electrodes reaches twelve, the distortion of the deep-site dose distribution is still small.…”

Comprehensive evaluation and new recommendations in the use of Gafchromic EBT3 film

“…Their characterization of the absolute change in netOD over time showed that film irradiated to higher doses had a greater absolute change in netOD over time. Pocza et al 22 . evaluated darkening long‐term of EBT2 film after irradiation to up to 2 Gy and found that OD increased by up to 15% for films scanned with the red channel at 18 months after irradiation relative to the original scan at 24 h. Fuss et al 23 .…”

“…21 Their characterization of the absolute change in netOD over time showed that film irradiated to higher doses had a greater absolute change in netOD over time. Pocza et al 22 evaluated darkening long-term of EBT2 film after irradiation to up to 2 Gy and found that OD increased by up to 15% for films scanned with the red channel at 18 months after irradiation relative to the original scan at 24 h. Fuss et al 23 reported that EBT film irradiated to 0.9-8.1 Gy and scanned 4 months later showed a 5.4%-12.4% increase in netOD relative to the netOD measured at 24 h. From these data, we can conclude that beyond 24 h, the extent of darkening in irradiated film is less severe than during the first few hours after irradiation. However, we found that the netOD continued to increase beyond 24 h (Figure 1) and that this will continue for several months after irradiation (Figure 2).…”

A Comparison of Film Analysis Software for Radiotherapy Patient-Specific Quality Assurance

“…The user experience varies signi cantly among each software, making a comparison valuable. To date, there has been limited investigation into comparing RCF software [5]. Such a comparison is bene cial, as RCF is commonly employed by radiotherapy departments for stereotactic PSQA.…”