Comparison of the Tada Formula With Software Slicer

Abstract

Background and Purpose— The Tada (ABC/2) formula has been used widely for volume assessment of intracerebral hematoma. However, the formula is crude for irregularly shaped hematoma. We aimed to compare the accuracy of the ABC/2 formula with open source software Slicer. Methods— Computed tomographic images of 294 patients with spontaneous intracerebral hematoma were collected. Hematoma volumes were assessed with the ABC/2 formula and calculated with software 3D Slicer. Results of these 2 methods were compared with regard to hematoma size and shape. Results— The estimated hematoma volume was 58.41±37.83 cm 3 using the ABC/2 formula, compared with 50.38±31.93 cm 3 with 3D Slicer (mean percentage deviation, 16.38±9.15%). When allocate patients into groups according to hematoma size, the mean estimation error were 3.24 cm 3 (17.72%), 5.85 cm 3 (13.72%), and 15.14 cm 3 (17.48%) for groups 1, 2, and 3, respectively. When divided by shape, estimation error was 3.33 cm 3 (9.76%), 7.19 cm 3 (18.37%), and 29.39 cm 3 (39.12%) for regular, irregular, and multilobular hematomas. Conclusions— There is significant estimation error using the ABC/2 formula to calculate hematoma volume. Compared with hematoma size, estimation error is more significantly associated with hematoma shape.

Retrospective Validation of a Computer-Assisted Quantification Model of Intracerebral Hemorrhage Volume on Accuracy, Precision, and Acquisition Time, Compared with Standard ABC/2 Manual Volume Calculation

“…22,23 It is also wellacknowledged that ABC/2 tends to overestimate lesion volumes. 24,25 In our study, ABC/2 overestimated ICH volume by 45%, on average. While the mean SegTool measurements were .…”

Development and Validation of an Automatic Segmentation Algorithm for Quantification of Intracerebral Hemorrhage

“…13,15,21 Especially in larger hematomas, we observed disagreement between raters as well as systematic volume overestimation by 30% on average ( Figure 2B). In 2 trials evaluating the benefit of surgery versus initial conservative treatment in ICH, larger and superficial hematomas were significantly more likely to cross over and receive surgery, despite initial randomization to conservative treatment.…”

A nested mechanistic sub-study into the effect of tranexamic acid versus placebo on intracranial haemorrhage and cerebral ischaemia in isolated traumatic brain injury: study protocol for a randomised controlled trial (CRASH-3 Trial Intracranial Bleeding Mechanistic Sub-Study [CRASH-3 IBMS])

“…Whilst some researchers have found that the ABC/2 method overestimates lesion volume compared to computer-assisted methods [39, 44, 45, 47, 51–55], others claim the opposite [41, 56]. Haemorrhagic lesions that have a regular shape are more accurately estimated using the ABC/2 method compared to lesions with irregular or multi-lobular shapes [43, 45–56].…”