Comparison of the socio-demographic and clinical features of pulmonary TB patients infected with sub-lineages within the W-Beijing and non-Beijing Mycobacterium tuberculosis

Hu, Yi; Mathema, Barun; Zhao, Qi; Zheng, Xubin; Li, Dange; Jiang, Weili; Wang, Weibing; Xu, Biao

doi:10.1016/j.tube.2015.11.007

Cited by 17 publications

(14 citation statements)

References 33 publications

(41 reference statements)

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“…And they were identified as the causative agents of tuberculosis in the world. For each families of MTB resistance to rifampicin, the prevalence was analyzed for the selected studies as follows: Beijing nineteen studies [14, 15, 16, 17, 18, 19, 20, 21, 22, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31], LAM ten studies [15, 17, 23, 25, 28, 29, 32, 33, 34, 35], T ten studies [3, 15, 16, 17, 23, 27, 28, 32, 34, 35], EAI eight studies [18, 22, 25, 27, 28, 29, 33, 36], Ural four studies [15, 17, 30, 34] Haarlem five studies [15, 23, 25, 28, 34], CAS four studies [15, 29, 30, 35] and MANU two studies [16, 29]. The proportion of rifampicin resistance varies by the type of regions and strains.…”

Section: Resultsmentioning

confidence: 99%

“…In this review, eight studies were included from Western Pacific Region, of these seven were from China. According to these studies, Beijing family was the most rifampicin-resistance strains [14, 16, 20, 22]. On the other hand, there were many reports on rifampicin resistance MTB from Eastern Mediterranean Region and African Region but most of the studies relied on gen-expert method or culture based drug susceptibility test that has no ability to identify the strain or family of MTB [40].…”

Section: Resultsmentioning

confidence: 99%

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Resistance of Mycobacterium tuberculosis strains to Rifampicin: A systematic review and meta-analysis

Feyisa

Abdurahman

Jimma

et al. 2019

Heliyon

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IntroductionAntitubercular drug resistance strain is a horrifying barrier to effective TB treatment and prevention. The present study aimed to determine the prevalence and geographical distribution of rifampicin-resistance M. tuberculosis (MTB) strains.MethodsWe searched two electronic databases, PubMed and EMBASE, until 26 March 2017 and updated our search on 27 April 2018 and accessed all prevalence studies of MTB strain and their drug susceptibility patterns to rifampicin. The pooled prevalence estimate was determined using random effects model.ResultsWe identified 23 studies satisfying the inclusion criteria. The proportion of rifampicin resistance strains was diverged depending on the type of strains, country and Regions. The pooled estimate of rifampicin-resistance strains of MTB for the included studies was 4% (95% CI: 3–5%). In subgroup analysis based on World Health Organization (WHO) Regions, the pooled estimate of rifampicin-resistance strains of MTB was 11% (95% CI: 9–13%) with the Western Pacific Region 24%, Europian Region 10%, South-East Asian Region 6%, African Region 3% and Region of American 1%. Beijing family was the most dominant strain resistance to rifampicin with pooled prevalence of 14% (95% CI: 10–18%). The pooled prevalence of other families, i.e. EAI, T, CAS, MANU, Haarlem, LAM and Ural, was ≤2% for each.ConclusionHigh burden of rifampicin resistance MTB strains was identified in the Western Pacific Region. Of these, Beijing family was predominantly resistance to rifampicin in Western Pacific Region and South-East Asian Region and also spread to European Region and Region of American.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Resistance of Mycobacterium tuberculosis strains to Rifampicin: A systematic review and meta-analysis

Feyisa

Abdurahman

Jimma

et al. 2019

Heliyon

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“…We also found that lineage 3 strains were associated with reduced risk of transmission chains in Europe and the Americas, which is consistent with the findings from a household contact study in Montreal [ 51 ]. In contrast, we found that Beijing family strains may be more likely to cause transmission chains, which could reflect the ability of Beijing strains to spread quickly through human populations [ 46 , 52 , 53 ]. These findings are not consistent with previous work that showed no differences between lineages in transmission from household contacts [ 46 , 54 , 55 ].…”

Section: Discussionmentioning

confidence: 99%

Global variation in bacterial strains that cause tuberculosis disease: a systematic review and meta-analysis

Wiens

Woyczynski

Ledesma

et al. 2018

BMC Med

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BackgroundThe host, microbial, and environmental factors that contribute to variation in tuberculosis (TB) disease are incompletely understood. Accumulating evidence suggests that one driver of geographic variation in TB disease is the local ecology of mycobacterial genotypes or strains, and there is a need for a comprehensive and systematic synthesis of these data. The objectives of this study were to (1) map the global distribution of genotypes that cause TB disease and (2) examine whether any epidemiologically relevant clinical characteristics were associated with those genotypes.MethodsWe performed a systematic review of PubMed and Scopus to create a comprehensive dataset of human TB molecular epidemiology studies that used representative sampling techniques. The methods were developed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). We extracted and synthesized data from studies that reported prevalence of bacterial genotypes and from studies that reported clinical characteristics associated with those genotypes.ResultsThe results of this study are twofold. First, we identified 206 studies for inclusion in the study, representing over 200,000 bacterial isolates collected over 27 years in 85 countries. We mapped the genotypes and found that, consistent with previously published maps, Euro-American lineage 4 and East Asian lineage 2 strains are widespread, and West African lineages 5 and 6 strains are geographically restricted. Second, 30 studies also reported transmission chains and 4 reported treatment failure associated with genotypes. We performed a meta-analysis and found substantial heterogeneity across studies. However, based on the data available, we found that lineage 2 strains may be associated with increased risk of transmission chains, while lineages 5 and 6 strains may be associated with reduced risk, compared with lineage 4 strains.ConclusionsThis study provides the most comprehensive systematic analysis of the evidence for diversity in bacterial strains that cause TB disease. The results show both geographic and epidemiological differences between strains, which could inform our understanding of the global burden of TB. Our findings also highlight the challenges of collecting the clinical data required to inform TB diagnosis and treatment. We urge future national TB programs and research efforts to prioritize and reinforce clinical data collection in study designs and results dissemination.Electronic supplementary materialThe online version of this article (10.1186/s12916-018-1180-x) contains supplementary material, which is available to authorized users.

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“…After evaluating the potential documents, 41 eligible studies were identified [ [13] , [14] , [15] , [16] , [17] , [18] , [19] , [20] , [21] , [22] , [23] , [24] , [25] , [26] , [27] , [28] , [29] , [30] , [31] , [32] , [33] , [34] , [35] , [36] , [37] , [38] , [39] , [40] , [41] , [42] , [43] , [44] , [45] , [46] , [47] , [48] , [49] , [50] , [51] , [52] , [53] ]. These studies were conducted between 2006–2020 in Europe, Latin America, Asia, and Africa.…”

mentioning

confidence: 99%

Beijing genotype of Mycobacterium tuberculosis is associated with extensively drug-resistant tuberculosis: A global analysis

Karbalaei

Majidzadeh

2021

New Microbes and New Infections

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Comparison of the socio-demographic and clinical features of pulmonary TB patients infected with sub-lineages within the W-Beijing and non-Beijing Mycobacterium tuberculosis

Cited by 17 publications

References 33 publications

Resistance of Mycobacterium tuberculosis strains to Rifampicin: A systematic review and meta-analysis

Resistance of Mycobacterium tuberculosis strains to Rifampicin: A systematic review and meta-analysis

Global variation in bacterial strains that cause tuberculosis disease: a systematic review and meta-analysis

Beijing genotype of Mycobacterium tuberculosis is associated with extensively drug-resistant tuberculosis: A global analysis

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