Comparison of the results of renal transplants from conventional and non-heart-beating cadaveric donors

Nicholson, M. L.; Horsburgh, T.; Doughman, T; Wheatley, T. J.; Butterworth, P.C.; Veitch, P. S.; Bell, P. R. F.

doi:10.1016/s0041-1345(96)00605-7

Cited by 32 publications

(20 citation statements)

References 3 publications

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“…from The Netherlands, as well as multiple other studies (4)(5)(6)(7)(8)(9)(10)14,(18)(19)(20), DCD kidneys in our study showed a statistically higher incidence of DGF. Despite this higher incidence of delayed function, there was no difference in 5-year graft or patient survival between DCD and DBD donor kidneys in our study.…”

Section: Uncontrolled Dcd Donorssupporting

confidence: 80%

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Expanding the Donor Kidney Pool: Utility of Renal Allografts Procured in a Setting of Uncontrolled Cardiac Death

Singh

Matsuoka

Mateo

et al. 2006

American Journal of Transplantation

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The chronic shortage of deceased kidney donors has led to increased utilization of donation after cardiac death (DCD) kidneys, the majority of which are procured in a controlled setting. The objective of this study is to evaluate transplantation outcomes from uncontrolled DCD (uDCD) donors and evaluate their utility as a source of donor kidneys. Concerted efforts should be focused on procurement of uDCD donors, which can provide another source of quality deceased donor kidneys.

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Section: Uncontrolled Dcd Donorssupporting

confidence: 80%

“…The use of DCD donors has been reported to increase the available donor pool by 16-40% (8,15,22,23). An audit out of a Washington, DC, hospital found 5-6 times as many potential DCD donors as potential DBD donors (24), and a Canadian study estimated a potential increase of 30-87% with the incorporation of DCD donor kidneys (25).…”

Section: Uncontrolled Dcd Donorsmentioning

confidence: 99%

Expanding the Donor Kidney Pool: Utility of Renal Allografts Procured in a Setting of Uncontrolled Cardiac Death

Singh

Matsuoka

Mateo

et al. 2006

American Journal of Transplantation

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“…While some studies have shown poorer graft survival for NHBD kidneys103,105, others have demonstrated favourable graft survival compared with HBDs25,91,112,113. This is despite the detrimental effects of warm ischaemic damage in NHBDs with consequent high rates of DGF.…”

Section: Discussionmentioning

confidence: 99%

Non Heart-Beating Donors in England

Chaib

2008

Clinics

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Chaib E. Non heart-beating-donors in England. Clinics. 2008;63(1):121-34. When transplantation started all organs were retrieved from patients immediately after cardio-respiratory arrest, i.e. from nonheart-beating donors. After the recognition that death resulted from irreversible damage to the brainstem, organ retrieval rapidly switched to patients certified dead after brainstem testing. These heart-beating-donors have become the principal source of organs for transplantation for the last 30 years. The number of heart-beating-donors are declining and this is likely to continue, therefore cadaveric organs from non-heart-beating donor offers a large potential of resources for organ transplantation. The aim of this study is to examine clinical outcomes of non-heart-beating donors in the past 10 years in the UK as an way of decreasing pressure in the huge waiting list for organs transplantation. KEYWORDS:Transplantation. Liver. Kidney. Donors.The imbalance between supply of organs for transplantation and demand for them is widening all over the world. In the United Kingdom (UK) the figures are not different, by the end of December 2004 there were over 6000 people on the active waiting list for organ transplantation. Recent data suggest that over 400 of these people will die each year before a new organ becomes available.

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“…Despite the increased incidence of DGF, initial concerns about the prognosis of kidney transplantation from DCD donors have lessened, as multiple studies have reported short-term and medium-term outcomes in kidneys transplanted from DCD donors that are comparable to kidneys transplanted from donation after brain death (DBD) donors (6)(7)(8)(9)(15)(16)(17)(18)(19). This observation implies that the causes of allograft loss may differ for DCD and DBD donor kidney transplant recipients.…”

mentioning

confidence: 99%

Kidney transplantation from donation after cardiac death donors: lack of impact of delayed graft function on post‐transplant outcomes

Singh¹,

Farney²,

Rogers³

et al. 2011

Clinical Transplantation

129

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Comparison of the results of renal transplants from conventional and non-heart-beating cadaveric donors

Cited by 32 publications

References 3 publications

Expanding the Donor Kidney Pool: Utility of Renal Allografts Procured in a Setting of Uncontrolled Cardiac Death

Expanding the Donor Kidney Pool: Utility of Renal Allografts Procured in a Setting of Uncontrolled Cardiac Death

Non Heart-Beating Donors in England

Kidney transplantation from donation after cardiac death donors: lack of impact of delayed graft function on post‐transplant outcomes

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