Comparison of the Preventive Activity of Isorhamnetin Glycosides from Atsumi-kabu (Red Turnip,<i>Brassica, campestris</i>L.) Leaves on Carbon Tetrachloride-Induced Liver Injury in Mice

Igarashi, Kiharu; Mikami, Taisei; Takahashi, Yoshihiko; Sato, Hiroki

doi:10.1271/bbb.70558

Cited by 27 publications

(14 citation statements)

References 24 publications

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“…Isorhamnetin‐3‐ O ‐glucoside ( 62 ), a well‐known flavonoid present in turnip root was found to be able to suppress the levels of plasma alkaline phosphatase (ALT) and alanine transaminase (AST) in mice with CCl 4 ‐induced liver injuries, while its analog isorhamnetin‐3,7‐di‐ O ‐glucoside ( 61 ) resulted in no suppression. The above results suggest that the additional 7‐O‐glucosyl moiety is unfavorable for mitigating liver injury (Igarashi, Mikami, Takahashi, & Sato, ). In another study, oral delivery of ethanolic extract of turnip after liver injury resulted in significant reduction of AST, ALT, and LDH enzyme activities in serum, and caused a reduction of the activities of catalase and SOD (superoxide dismutase) in liver microsomal cytosol (Choi et al., ).…”

Section: Pharmacological Activitiesmentioning

confidence: 96%

Phytochemical and Health‐Beneficial Progress of Turnip (Brassica rapa)

Paul

Geng

Yang

et al. 2018

Journal of Food Science

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Despite the advancement of medical science, diseases are part‐and‐parcel of human life. Plants have provided humans with medicines since time immemorial, and are still one of the primary sources for drug discovery. Brassica rapa L., commonly known as turnip, is one of the world's oldest cultivated vegetables. Besides being an important vegetable and source of oil, turnip is also used as a traditional medicine for the treatment of headaches, chest complaints, rheumatisms, oedemas, gonorrhoea, syphilis, and rabies. Glucosinolates and isothiocyanates (mainly 2‐phenylethyl, 4‐pentenyl, and 3‐butenyl derivatives) are the main constituents of turnip with diverse bioactivities, especially for the protective effect against cancers. Besides, flavonoids, phenolics, indoles and volatiles are also concomitant in this plant. Pharmacological investigation on turnip revealed the antitumor, antihypertensive, antidiabetic, antioxidant, antiinflammatory, hepatoprotective, and nephroprotective effects. The anticancer property was found to be the most promising biological activity of turnip with 2‐phenylethyl isothiocyanate, phenylpropionitrile, brassicaphenanthrene A, 6‐paradol, and trans‐6‐shogaol as the major active constituents. Flavonoids and phenolics with high free radical scavenging activity should be corresponding to the antioxidant effects. Arvelexin, an indole derivative in turnip, was reported with various effects involving antiinflamatory, antihypertensive and hypolipidemic potency. In spite of many studies concerning either the chemical constituents or the biological activities of turnip, only a few cases disclosed the active ingredients responsible for diverse bioactivities. This review summarizes the research progress on the chemistry and health‐benefits of turnip over the past 20 years to provide a reference for the further investigation.

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Section: Pharmacological Activitiesmentioning

confidence: 96%

Phytochemical and Health‐Beneficial Progress of Turnip (Brassica rapa)

Paul

Geng

Yang

et al. 2018

Journal of Food Science

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“…A completely red-skinned turnip, atsumi-kabu, has long been cultivated in some areas of Japan and is used for the production of pink, pickled turnips. Tests on the anthocyanins from the skin of these turnips gave significant improvement in the cholesterol levels of rats (Igarashi et al, 2008).…”

Section: Varietal Groupsmentioning

confidence: 98%

Swedes and Turnips

Gowers

2010

Root and Tuber Crops

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“…In the last three decades, traditional vegetables have attracted the interest of scholars in contemporary Japan [9][10][11][12][13]. Traditional vegetables have also become a measure of agricultural revitalization.…”

Section: Traditional Vegetables In Japanmentioning

confidence: 99%

Towards Evidence Based Policy Making in GIAHS: Convention Theory and Effects of GIAHS Registration on the Wholesale and Retail Trade of Traditional and Local Vegetables

et al. 2021

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This study examines how the registration of certain agricultural regions affects the sales of vegetables classified as traditional. We focused on the sales trends of traditional vegetables from the Noto region, one of the first designated sites of Globally Important Agricultural Heritage Systems (GIAHS). We compared the sales of recognized traditional vegetables to those of similar traditional vegetables from nearby areas and vegetables labeled with the same place names as the traditional vegetables but without elements of traditionality in branding. The study analyzed the sale and relevant trends of four categories of vegetable: Kaga vegetables, vegetables labeled “Kaga”, Noto vegetables, and vegetables labeled “Noto”. We further analyzed the trends by applying Convention Theory to understand the underpinning “orders of worth” in the purchase and sale of the items. Both Noto vegetables and place-labeled vegetables increased in overall sales since GIAHS registration in 2011. The recent increases in sales volume and number of items, however, were largely due to the production of lettuce, a crop from a vegetable factory. By applying Convention Theory, we identified that in the agriculture of the region, industrial farming impacted even the GIAHS registered site. Thus, careful collection and analysis of evidence is necessary to evaluate the effects of GIAHS registration and draft an action plan for further evidence-based policy making.

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Comparison of the Preventive Activity of Isorhamnetin Glycosides from Atsumi-kabu (Red Turnip,Brassica, campestrisL.) Leaves on Carbon Tetrachloride-Induced Liver Injury in Mice

Cited by 27 publications

References 24 publications

Phytochemical and Health‐Beneficial Progress of Turnip (Brassica rapa)

Phytochemical and Health‐Beneficial Progress of Turnip (Brassica rapa)

Swedes and Turnips

Towards Evidence Based Policy Making in GIAHS: Convention Theory and Effects of GIAHS Registration on the Wholesale and Retail Trade of Traditional and Local Vegetables

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