Comparison of the prevalence and associated factors of interdialytic fatigue and post-dialysis fatigue among maintenance hemodialysis patients: A cross-sectional study

Abstract

Objective Interdialytic Fatigue (IDF) and post-dialysis fatigue (PDF) were the most common complication among maintenance hemodialysis (MHD) patients. However, the differences between IDF and PDF in MHD patients have been reported little and their concepts were easy to be confused by some studies. The purpose of this study was to compare the prevalence of fatigue and investigate the differences in the contributing factors between IDF and PDF in patients receiving MHD therapy. Methods In this cross-sectional study, 217 MHD patients, from a comprehensive hospital in China, were recruited and collected from January 2022 to June 2022. The Function assessment of Chronic Illness Therapy-Fatigue (FACIT-F) was adopted to measure IDF and PDF. Psychosocial factors included resilience, quality of sleep, and social support which were estimated by the 10-item Connor-Davidson Resilience Scale(CD-RISC), Pittsburgh Sleep Quality Index(PSQI), and Social Support Rate Scale(SSRS), respectively. Multiple logistic regression analyses were performed to identify influencing factors of IDF and PDF in patients on MHD therapy. Results The prevalence of IDF and PDF was 29.0% and 61.8%, respectively, and With 96.8% of MHD patients with IDF suffered from PDF. Multiple logistic regression analysis revealed that the independent factors of fatigue were age(p < .001), resilience(p < .001), and sleep quality(p = .001) and age(p = .007), resilience(p < .001), and intradialytic hypotension (IDH) (p < .001) were contributing factors of PDF. Conclusion The prevalence of PDF was significantly higher than IDF among MHD patients. Age and resilience were common independent factors of fatigue and PDF.