Comparison of the nutritional value and biological activities of the acetone, methanol and water extracts of the leaves of Solanum nigrum and Leonotis leonorus

Jimoh, Oluseyi F; Adedapo, Adeolu Alex; Afolayan, A. J.

doi:10.1016/j.fct.2010.01.007

Cited by 88 publications

(55 citation statements)

References 35 publications

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“…The results showed the presence of alkaloids, flavonoids, steroids, tannins, Phenols, Carbohydrates, Protein, Protein and Glycosides, as reported by some previous researchers [44][45][46], who have described the presence of phytocomponents in A. indica and cinnamon spice. These phytocomponents are considered as useful phytocomponents that not only enhance the action of anti-infla mmatory, antidiabetic, analgesic, central nervous system activities and nutritional value in the system but also act against disease causing organisms, thus conferring potential benefits by protecting from diseases.…”

Section: Discussionsupporting

confidence: 63%

In vitro Antimicrobial Activity of Azadirachta indica (Leaves) against Fish Pathogenic Bacteria Isolated from Naturally Infected Dawkinsia filamentosa (Blackspot barb)

Kavitha¹,

Raja²,

Kamaraj³

et al. 2017

Med Aromat Plants

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To examine the antibacterial activity of ethyl acetate, ethanol and methanol extracts of Azadirachta indica (A. indica) on fish pathogens viz., Aeromonas veronii, Aeromonas hydrophila, Acinetobacter junii, Acinetobacter tandoii, Acinetobacter spp. and Pseudomonas stutzeri isolated from diseased blackspot barb, Dawkinsia filamentosa. The naturally infected fish, D. filamentosa were collected from Mettur Dam and the associated bacteria in the ulcerative lesions were isolated, sequenced the amplified product and tentatively identified through sequence similarity. The leaves powder was extracted successively with 250 ml of ethyl acetate, ethanol and methanol solvents by using Soxhlet extractor for 8 h at a temperature not exceeding the boiling point of the solvent. Ethyl acetate, ethanol and methanol extracts were subjected to phytochemical analysis as well as the antimicrobial assay using agar well diffusion method. Totally six fish bacterial pathogens were isolated from the ulcerative of lesions blackspot barb fish (D. filamentosa). All the gene sequences were deposited in the NCBI and received their accession numbers. The isolated strains were: A. veronii (KX688046), P. stutzeri (KX721473), A. hydrophila (KX756709), A. spp. (KX775221), A. junii (KX756708) and A. tandoii (KX775222). The different crude extracts of A. indica showed significant inhibitory effects on all the isolates. In which, the ethyl acetate extract showed maximum zone of inhibition on against P. stutzeri (23 mm) A. junii (22 mm), A. hydrophila (19 mm) and A. tandoii (18 mm). The ethanol extract showed moderate zone of inhibition on A. junii (15 mm) and A. veronii (14 mm) and also the methanol extract on A. junii (15 mm) and A. veronii (14 mm). The present study revealed that the crude extracts A. indica leaves possesses significant antibacterial activity on isolated fish pathogens. The susceptibility test was conducted on isolates using antibiotics, selected based on their importance to human medicine and on fish production. To conclude the present findings the ethyl acetate leaf extracts could be used as potential sources of antimicrobial agents.

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Section: Discussionsupporting

confidence: 63%

In vitro Antimicrobial Activity of Azadirachta indica (Leaves) against Fish Pathogenic Bacteria Isolated from Naturally Infected Dawkinsia filamentosa (Blackspot barb)

Kavitha¹,

Raja²,

Kamaraj³

et al. 2017

Med Aromat Plants

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“…Proanthocyanidins content was highest in the water extract of the stem (147.17± 2.99 mg/g), followed by the leaf (118.61±7.00 mg/g) and the root (102.32±7.87 mg/g had the least. The high proanthocyanidins content recorded in leaf water extract in this study is in contrast to the report of Jimoh et al (2010). The difference data could be attributed to place and time of collection of sample, as well as age of the plant.…”

contrasting

confidence: 56%

<i>In vitro</i> anti-radical activities of extracts of <i>Solanum nigrum</i> (L.) from South Africa

Gbadamosi¹,

Afolayan²

2016

J. App. Bioscience.

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Objective: Solanum nigrum (black nightshade) is a wild vegetable with many ethnomedicinal uses. This study evaluated the quantitative phytochemical components, in vitro antioxidant and antibacterial activities of extracts of S. nigrum with the aim of providing more information on its therapeutic potential in the management of metabolic and infectious diseases. Methodology and Results: The phytochemicals components, antioxidant and antibacterial activities of the extracts were evaluated using standard laboratory techniques. The phenols content was significantly higher in the ethanol extract of the berry (228.40±3.09 mg/g) than the water extract (132.2±1.23 mg/g) and the percentage saponins content was generally higher in the water extracts than the ethanol extracts of the plant. At 0.5 mg/ml, the water extracts exhibited higher ferrous reducing action and DPPH radicals scavenging activity than the ethanol extracts. The antioxidant activity of the ethanol extracts against nitric oxide radicals was higher than that of the water extracts. The ethanol extracts exhibited 100% antibacterial activity. Conclusion and Application of results: Solanum nigrum showed significant antioxidant and antibacterial activities. The polyphenol components of the plant could be responsible for the antioxidant and antibacterial activities observed in this study. The isolation and characterization of active compounds from various parts of S. nigrum could lead to the discovery of novel compounds that could present the plant as a valuable candidate in the management of diseases. The plant could be important in the management of bacterial related infectious diseases. Powder and tincture prepared from the leaves could be used as antibacterial remedy. However, antifungal screening of the plant will further confirm its anti-infective status. Based on its antioxidant activity, the leaves of S. nigrum could be a good source of natural antioxidant with considerable therapeutic effect in the management of metabolic diseases such as diabetes, obesity, hyperlipidemia, atherosclerosis, hypertension and cancer. This study forms basis for future research activities on extracts and active compounds of S. nigrum for bioactivity in chronic diseases.

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“…It also has attracted increasing interest in the process of searching anticancer Chinese medicines, since it is a prolific producer of secondary metabolites such as solasonine, solasnine, oleic acid, linolic acid, and saponins (Saijo et al, 1982;Tsuyoshi et al, 2000). And, some of these constituents are well-known for their pharmacological and biological activities Jimoh et al, 2010;Yang et al, 2010). This herb grows wild in many provinces of the China.…”

Section: Introductionmentioning

confidence: 99%

Fingerprint quality detection ofSolanum nigrumusing high-performance liquid chromatography–evaporative light scattering detection

Wang

Gao

Bai

et al. 2011

Pharmaceutical Biology

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Comparison of the nutritional value and biological activities of the acetone, methanol and water extracts of the leaves of Solanum nigrum and Leonotis leonorus

Cited by 88 publications

References 35 publications

In vitro Antimicrobial Activity of Azadirachta indica (Leaves) against Fish Pathogenic Bacteria Isolated from Naturally Infected Dawkinsia filamentosa (Blackspot barb)

In vitro Antimicrobial Activity of Azadirachta indica (Leaves) against Fish Pathogenic Bacteria Isolated from Naturally Infected Dawkinsia filamentosa (Blackspot barb)

<i>In vitro</i> anti-radical activities of extracts of <i>Solanum nigrum</i> (L.) from South Africa

Fingerprint quality detection ofSolanum nigrumusing high-performance liquid chromatography–evaporative light scattering detection

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