Comparison of the Myopia Control Effectiveness and Defocus of OK and HAL in Adolescents

Abstract

Purpose To compare the control effectiveness and periretinal defocus between orthokeratology(OK) and highly aspherical lenslets(HAL) in adolescents with myopia. Methods In this prospective study, 211 children( 211 eyes) were enrolled in Beijing Ming Vision and Ophthalmology between October 2022 and February 2023. According to the myopic correction method, the children were divided into three subgroups: OK, HAL, and Single-Vision spectacles (SVS); according to the spherical equivalent (SE), they were further divided into two subgroups: A-1.0 ≤ SE≤-2.0D, B-2.0<SE≤-3.0 D.All children were followed up for12mo,and the changes in axial length and periretinal defocus before and after treatment were recorded and the factors affecting the corneal shaping force for one day post-OK were analyzed. Results AL growth in the OK and HAL was lower than that in the SVS after 6,9,12mo. Comparison of the difference in the amount of AL change between OK and HAL: 6mo( Z=-1.367 ,P = 0.317) ; 9mo(Z=-1.45, P = 0.211) ;12mo( Z=-1.52, P = 0.365 ), the difference was not statistically significant with (-1.0 ≤ SE≤-2.0D). The myopic defocus of RDV270-300° in the HAL subgroup was higher than that in the OK subgroup(Z = 1.382,P = 0.016),and in other areas,the myopic defocus was higher in the OK subgroup. Em,SRI ,and corneal thickness were significantly associated with shaping force. Conclusions OK is one of the most effective optical treatments for controlling myopia and the factors that affect the corneal shaping force under different corneal parameters are different.For mild myopia, HAL can achieve the same effectiveness as OK.