Comparison of the Macronutrient Content of Colostrum: Locals with Refugees

Özmen, Esra Beşer; Okman, Esin; Sarı, Fatma Nur; Keser, Merve Kucukoglu; Dizdar, Evrim Alyamaç; Tayman, Cüneyt; Oğuz, Şerife Suna

doi:10.1089/bfm.2020.0085

Cited by 3 publications

(2 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Aging may cause changes in the mammary glands. However, the effects of maternal age on milk protein remain controversial [ 40 , 54 , 55 ]. Further research is needed to investigate the underlying mechanism of this association.…”

Section: Discussionmentioning

confidence: 99%

Longitudinal Changes in the Concentration of Major Human Milk Proteins in the First Six Months of Lactation and Their Effects on Infant Growth

et al. 2021

View full text Add to dashboard Cite

Our knowledge related to human milk proteins is still limited. The present study determined the changes in multiple human milk proteins during the first six months of lactation, investigated the influencing factors of milk proteins, and explored the impact of milk proteins on infant growth. A total of 105 lactating women and their full-term infants from China were prospectively surveyed in this research. Milk samples were collected at 1–5 days, 8–14 days, 1 month, and 6 months postpartum. Concentrations of total protein and α-lactalbumin were measured in all milk samples, and concentrations of lactoferrin, osteopontin, total casein, β-casein, αs−1 casein, and κ-casein were measured in milk from 51 individuals using ultra performance liquid chromatography coupled with mass spectrometry. The concentration of measured proteins in the milk decreased during the first six months of postpartum (p-trend < 0.001). Maternal age, mode of delivery, maternal education, and income impacted the longitudinal changes in milk proteins (p-interaction < 0.05). Concentrations of αs−1 casein in milk were inversely associated with the weight-for-age Z-scores of the infants (1 m: r −0.29, p 0.038; 6 m: r −0.33, p 0.020). In conclusion, the concentration of proteins in milk decreased over the first six months postpartum, potentially influenced by maternal demographic and delivery factors. Milk protein composition may influence infant weights.

show abstract

Section: Discussionmentioning

confidence: 99%

Longitudinal Changes in the Concentration of Major Human Milk Proteins in the First Six Months of Lactation and Their Effects on Infant Growth

et al. 2021

View full text Add to dashboard Cite

show abstract

“…The higher UMP content in the breast milk of the highly educated lactating mothers might be related to the intake of dairy. In previous studies, the relationship of macronutrients and fat-soluble vitamins in breast milk with maternal demographic characteristics and dietary habits has been systematically examined [ 30 , 31 , 32 ]. However, the TPAN concentration of breast milk in relation to the maternal demographic characteristics and dietary habits has not been reported, and needs to be further explored.…”

Section: Discussionmentioning

confidence: 99%

Profile of Nucleotides in Chinese Mature Breast Milk from Six Regions

et al. 2022

View full text Add to dashboard Cite

This study measured the total potentially available nucleoside (TPAN) content in breast milk from six different regions of China as a part of the Maternal Nutrition and Infant Investigation (MUAI) study. A total of 631 breast milk samples were collected from healthy, lactating women with singleton, full-term pregnancies between 40 and 45 days postpartum in Changchun, Chengdu, Lanzhou, Shanghai, Tianjin, and Guangzhou. TPAN and free 5′-monophosphate nucleotide (5′-MNT) contents were determined by high-performance liquid chromatography. The TPAN content of the Chinese mature milk ranged from 11.61 mg/L to 111.09 mg/L, with a median level of 43.26 mg/L. Four types of nucleotides were identified, and the median levels of cytidine monophosphate (CMP), uridine monophosphate (UMP), guanosine monophosphate (GMP), and adenosine monophosphate (AMP) were 22.84 mg/L, 9.37 mg/L, 4.86 mg/L, and 4.80 mg/L, respectively. CMP was the predominant nucleotide, accounting for 52.9% of the TPAN content, while free 5′-MNT accounted for 18.38% of the TPAN content. The distribution pattern of the TPAN content and level of the individual nucleotides were significantly different among the selected regions (p < 0.05), but the result showed no significant differences in the TPAN level in breast milk (p > 0.05). In addition, no correlation was reported between the geographic distribution and TPAN levels. This result showed that TPAN better reflects the level of total potential nucleosides in Chinese breast milk rather than 5′-MNT in free form. CMP, UMP, GMP, and AMP are the only 4 types of nucleotides reported in all detections. In addition, results revealed a large variation of TPAN levels in Chinese breast milk across six regions, so that the median value may not be the optimal fortification level of TPAN for Chinese infant populations.

show abstract

We Need Scientific, Ethical Articles on Infant Feeding

Jolly¹

2022

Breastfeeding Medicine

View full text Add to dashboard Cite

show abstract

Comparison of the Macronutrient Content of Colostrum: Locals with Refugees

Cited by 3 publications

References 25 publications

Longitudinal Changes in the Concentration of Major Human Milk Proteins in the First Six Months of Lactation and Their Effects on Infant Growth

Longitudinal Changes in the Concentration of Major Human Milk Proteins in the First Six Months of Lactation and Their Effects on Infant Growth

Profile of Nucleotides in Chinese Mature Breast Milk from Six Regions

We Need Scientific, Ethical Articles on Infant Feeding

Contact Info

Product

Resources

About