Comparison of the Incidence of Emergence Agitation Between Sevoflurane and Desflurane in Pediatric Patients

Abstract

Introduction: Emergence delirium is a state of aggressive delirium that can occur temporarily in the process of emerging from anaesthesia, and occurs most often during the early stages of emergence1. Newer volatile agents like sevourane and desurane are said to have a 20-80% increased incidence of adverse emergence effects when compared to halothane and isourane. This study was undertaken with the Aims And Objectives: aim of prospectively comparing the incidence of emergence agitation between sevourane and desurane in pediatric patients. To compare the pain intensity at 10 minutes, 20 minutes, 30 minutes, 45 minutes, 1 hour and 2 hours. To compare the time for tracheal extubation after discontinuing volatile agents in both groups. This prospective randomized control study study was c Materials And Methods: arried out in 60 pediatric patients between the age group 3-12 years undergoing elective surgeries under general anaesthesia. Patients were randomized into the following 2 groups: GROUP S - Anaesthesia was maintained with oxygen, nitrous oxide and sevourane (MAC 1). GROUP D - Anaesthesia was maintained with oxygen, nitrous oxide and desurane (MAC 1). Comparison between Age, gender, ASA, weights, D Results: uration of Inhalation Exposure(mins), Time for Extubation after discontinuing volatile(mins), PAED Score with Groups by Mann- Whitney U test, VAS Score with Groups by Unpaired ttest with Groups shows no statistical signicant association. Des Conclusion: urane has faster recovery from anaesthesia when compared to sevourane in pediatric patients. Incidence of emergence agitation is comparable between both the groups although sevourane has a slightly higher incidence of EA than desurane in our study.