Comparison of the Enantioselectivity of Phenethyl- and Naphthylethyl-Carbamate Substituted Cyclodextrin Bonded Phases

Hilton, M. L.; Chang, San Chun; Gasper, Mary P.; Pawłowska, Maria; Armstrong, Daniel W.; Stalcup, Apryll M.

doi:10.1080/10826079308020902

Cited by 22 publications

(6 citation statements)

References 6 publications

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“…With CSPs based on substituted cyclodextrins it is largely agreed that, in hexane-isopropanol mobile phases, there is no inclusion phenomenon but that the stationary phases act as a Pirkle-type CSPs [6,7]. According to the three point rule, classically used for the Structure of the racemic solutes.…”

Section: Resultsmentioning

confidence: 99%

Chromatographic properties in normal-mode HPLC of chiral stationary phases based on substituted β-cyclodextrins

et al. 1997

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SummarySubstituted 13-cyclodextrin chiral stationary phases having different types of phenyl carbamate substituents have been prepared and evaluated (retention, selectivity, resolution) for the liquid chromatographic separation of several series of enantiomers. The influence on separations of the degree of substitution and the structure of the substituent are discussed. Different mechanisms are suggested to explain separations in normal mode conditions.

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Section: Resultsmentioning

confidence: 99%

Chromatographic properties in normal-mode HPLC of chiral stationary phases based on substituted β-cyclodextrins

et al. 1997

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“…Stalcup and Gahm [82] showed that CSPs containing sulfated b-CD can be applied to the chiral resolution of various drug classes. Naphthylethylcarbamate derivatized b-CD phases show increased selectivity due to the formation of additional p-p-interactions [83,84]. The chiral recognition mechanism, however, is postulated to depend greatly on the mobile phase mode.…”

Section: Direct Methodsmentioning

confidence: 99%

Chiral separation by chromatographic and electromigration techniques. A Review

Gübitz

Schmid

2001

Biopharm & Drug Disp

225

135

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This review gives a survey of different chiral separation principles and their use in high-performance liquid chromatography (HPLC), gas chromatography (GC), supercritical fluid chromatography (SFC), thin-layer chromatography (TLC), capillary electrophoresis (CE) and capillary electrochromatography (CEC) highlighting new developments and innovative techniques. The mechanisms of the different separation principles are briefly discussed and some selected applications are shown.

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“…Now, various carbamates including chlorinated and methylsubsituted phenylcarbamates substituted CDs CSPs has been reported in [17][18][19], but only own one electrondonating group or one electron-withdrawing group. Y. Lin et al / J. Chromatogr.…”

Section: Introductionmentioning

confidence: 99%

Cyclodextrin clicked chiral stationary phases with functionalities-tuned enantioseparations in high performance liquid chromatography

Lin

Zhou

Tang

et al. 2015

Journal of Chromatography A

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Comparison of the Enantioselectivity of Phenethyl- and Naphthylethyl-Carbamate Substituted Cyclodextrin Bonded Phases

Cited by 22 publications

References 6 publications

Chromatographic properties in normal-mode HPLC of chiral stationary phases based on substituted β-cyclodextrins

Chromatographic properties in normal-mode HPLC of chiral stationary phases based on substituted β-cyclodextrins

Chiral separation by chromatographic and electromigration techniques. A Review

Cyclodextrin clicked chiral stationary phases with functionalities-tuned enantioseparations in high performance liquid chromatography

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