Comparison of the Emotional Effects of a Beta-Adrenergic Blocking Agent and a Tranquilizer under Different Situational Conditions

Erdmann, G; Janke, Wilhelm; Köchers, Sigrid; Terschlüsen, Brunhild

doi:10.1159/000118129

Cited by 21 publications

(3 citation statements)

References 8 publications

(11 reference statements)

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“…Though in a considerably high dosage, the beta-blocker yielded less effects on EDA during stress induced by physical exercise as compared to the benzodiazepine. Erdmann, Janke, K€ ochers, and Terschl€ usen (1984), in a 3 Â 3 factorial design with independent groups, assigned 108 male participants to either 40 mg oxprenolol, 5 mg diazepam, or placebo, following a double-blind design. Under each drug condition, two speech-anxiety groups and one control group were formed.…”

Section: Studies With Beta-blockers and Neurolepticsmentioning

confidence: 99%

Electrodermal Activity

Boucsein

2012

1,573

1,589

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except for brief excerpts in connection with reviews or scholarly analysis. Use in connection with any form of information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed is forbidden. The use in this publication of trade names, trademarks, service marks, and similar terms, even if they are not identified as such, is not to be taken as an expression of opinion as to whether or not they are subject to proprietary rights.Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com) Foreword to the Second EditionAs noted by David Lykken in the foreword to the first edition of this book, electrodermal activity was observed for the first time in Germany. A quartercentury later the scientific study of psychology also originated in Germany. Over time, however, the focus of psychological research, including the then new field of psychophysiology, shifted to the United States and Great Britain. This trend to the dominance of the United States and Great Britain was prolonged by the devastation of World War II and its aftermath in Germany (and elsewhere in continental Europe). Slowly at first and then more rapidly, German psychological science, including psychophysiology, recovered. For several decades German psychophysiologists have been a major force in psychophysiology. With the publication of the first English edition of this book in 1992, it became essential for electrodermal researchers worldwide again to learn from our German colleagues.When I came into psychophysiology in the mid-1960s, electrodermal activity was the most common system studied. Because of its popularity, a large literature had emerged on the physiological mechanisms producing these changes in the electrical properties of the skin and on the best methodology for recording them. Major reviews and/or chapters had been published or soon were to be published by Peter Venables and Irene Martin, Robert Edelberg, and David Lykken. Later reviews and articles were published by Venables and Margaret Christie, and by me. A chapter in 1990 by Michael Dawson, Anne Schell, and Diane Filion was especially noteworthy for its coverage of the psychological applications of electrodermal measures.Note that all these publications were journal articles and chapters and that most of them focused almost entirely on mechanisms and methodology. The publication of this book, first in German and then in English, provided the first book on electrodermal activity, and one that extensively covers psychological applications as well as mechanisms and methodology. Again to quote David Lykken back in 1992, "The return of German scholarship to what I shall loftily call the high table of psychophysiology is exemplified by this fine book, the most comprehensive treatise on the electrodermal system to appear in any language . . ." I completely agree with v that evaluation. Professor Boucsein's outstanding scholarship has produced a book of such breadth of coverage ...

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Section: Studies With Beta-blockers and Neurolepticsmentioning

confidence: 99%

Electrodermal Activity

Boucsein

2012

1,573

1,589

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“…β-Blocker use was excluded because a possible relationship of β-blockers to stress testing had been reported, and also because physicians tend to prescribe them for hypertensives who experience high levels of tension or neurosis [14]. Heart damage was assessed by abnormalities of electrocardiogram and chest x-ray; e.g.…”

Section: Methodsmentioning

confidence: 99%

Blood Pressure Biofeedback Treatment, Organ Damage and Sympathetic Activity in Mild Hypertension

Nakao

Nomura

Shimosawa

et al. 1999

Psychother Psychosom

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Background: Although biofeedback treatment is reported to be useful for patients with mild hypertension as an adjunct to medication, it is not certain whether the presence of organ damage affects its efficacy. The aim of this study is to clarify the clinical effects of biofeedback on mild hypertension in the absence and presence of organ damage. Methods: Eleven mildly hypertensive outpatients without damage to the heart, brain, retina or kidney (4 men and 7 women), aged 40–65 years, and 11 mildly hypertensive outpatients with target organ damage and matching variables for age, sex and medication were included in this study. They underwent biofeedback treatment once a week for a total of four sessions. Results: As a result of these sessions, mean blood pressures (MBP) in the organ-damage-negative (–) group and in the organ-damage-positive (+) group were significantly reduced by 12 ± 11 and 12 ± 8, respectively. The decrease was still significant 3 months after the treatment in the organ-damage (–) group, whereas no significant change was found 1 or 3 months after the treatment in the organ-damge (+) group. Throughout these sessions, the ratio of low frequency to high frequency of heart rate variance as well as systolic and MBP gradually decreased in each group (p < 0.01); this ratio of heart rate variance was smaller, and the α-wave amplitude on the electroencephalogram was larger in the organ-damage (–) group (p < 0.05). Conclusion: These results suggested that biofeedback intervention may be effective in mild hypertension, especially when the patient is organ damage (–). Sympathetic activity seems to play an important role in the differentiated response.

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“…This excludes human conflict paradigms that do not model a specific animal anxiety test in the first place [42,43,[60][61][62], or that have been investigated with fMRI only, but no fMRI (or other tissue oxygenation) data exist for the animal version [63,64]. Similarly, although stress and anxiety are closely interlinked [65], we exclude the large range of human stress tests that do not reflect animal paradigms, for example those that employ negative social feedback as stressor, such as public speaking paradigms [66][67][68].…”

Section: Cross-species Anxiety Testsmentioning

confidence: 99%

Cross-species anxiety tests in psychiatry: pitfalls and promises

Bach

2021

Mol Psychiatry

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Behavioural anxiety tests in non-human animals are used for anxiolytic drug discovery, and to investigate the neurobiology of threat avoidance. Over the past decade, several of them were translated to humans with three clinically relevant goals: to assess potential efficacy of candidate treatments in healthy humans; to develop diagnostic tests or biomarkers; and to elucidate the pathophysiology of anxiety disorders. In this review, we scrutinise these promises and compare seven anxiety tests that are validated across species: five approach-avoidance conflict tests, unpredictable shock anticipation, and the social intrusion test in children. Regarding the first goal, three tests appear suitable for anxiolytic drug screening in humans. However, they have not become part of the drug development pipeline and achieving this may require independent confirmation of predictive validity and cost-effectiveness. Secondly, two tests have shown potential to measure clinically relevant individual differences, but their psychometric properties, predictive value, and clinical applicability need to be clarified. Finally, cross-species research has not yet revealed new evidence that the physiology of healthy human behaviour in anxiety tests relates to the physiology of anxiety symptoms in patients. To summarise, cross-species anxiety tests could be rendered useful for drug screening and for development of diagnostic instruments. Using these tests for aetiology research in healthy humans or animals needs to be queried and may turn out to be unrealistic.

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Comparison of the Emotional Effects of a Beta-Adrenergic Blocking Agent and a Tranquilizer under Different Situational Conditions

Cited by 21 publications

References 8 publications

Electrodermal Activity

Electrodermal Activity

Blood Pressure Biofeedback Treatment, Organ Damage and Sympathetic Activity in Mild Hypertension

Cross-species anxiety tests in psychiatry: pitfalls and promises

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