Comparison of the Efficacy of Empiric Thoracic Vein Isolation for the Treatment of Paroxysmal and Persistent Atrial Fibrillation in Patients Without Structural Heart Disease

Abstract

In patients without underlying heart disease, the procedural outcome of an empiric thoracic vein isolation is comparable for PAF and PerAF.

Electrophysiological relation between the superior vena cava and right superior pulmonary vein in patients with paroxysmal atrial fibrillation

“…Second, an arrhythmogenic SVC is more likely observed in Asian than Western patients with AF as most prior studies focusing on arrhythmogenicity of the SVC are derived from Asian countries. 4,6,9,11,15,18 The present results may be different than those from other regions. Third, only intravenous isoproterenol infusion was used to induce AF.…”

“…Although the present results were clear, a prospective validation cohort may be warranted to evaluate clinical values of this novel finding. Second, an arrhythmogenic SVC is more likely observed in Asian than Western patients with AF as most prior studies focusing on arrhythmogenicity of the SVC are derived from Asian countries . The present results may be different than those from other regions.…”

“…The superior vena cava (SVC) is a main source of nonpulmonary vein (PV) ectopies that initiate atrial fibrillation (AF), particularly in Asian patients. Empiric SVC isolation in addition to PV isolation was reported to improve rhythm outcomes after catheter ablation of AF in prior randomized and nonrandomized studies . Because the SVC passes immediately adjacent to the right superior PV (RSPV) and the presence of muscular bundles/fibers connecting neighboring structures of the heart have been revealed by prior anatomical studies, we thought that anatomical and electrophysiological relations could be present between the two structures.…”

“…Empiric SVC isolation in addition to PV isolation was reported to improve rhythm outcomes after catheter ablation of AF in prior randomized and nonrandomized studies. [1][2][3][4] Because the SVC passes immediately adjacent to the right superior PV (RSPV) and the presence of muscular bundles/fibers connecting neighboring structures of the heart have been revealed by prior anatomical studies, [5][6][7][8] we thought that anatomical and electrophysiological relations could be present between the two structures. The present study aimed to estimate the interrelation between the SVC and RSPV by evaluating arrhythmogenic activities observed during catheter ablation of paroxysmal AF.…”

Geographic and racial representation and reported success rates of studies of catheter ablation for atrial fibrillation: Findings from the SMASH‐AF meta‐analysis study cohort

“…Currently, race and ethnicity and their stratified outcomes are rarely reported in the AF ablation literature, perpetuating this knowledge gap. Investigations of adjunctive lesion sets in homogenous populations by race or ethnicity that demonstrate incremental benefit may not generalize, contributing to reproducibility issues in the field …”