Comparison of the Efficacy of Three Different Bone Regeneration Materials: An Animal Study

Abstract

Objective The proposed study aimed to evaluate and compare the bone regeneration between commercially available hydroxyapatite–β-tricalcium phosphate (Ossifi; Equinox, the Netherlands), powdered polylactic acid (powdered PLA; Sigma-Aldrich, United States), and three-dimensionally printed PLA (3D-printed PLA; Cubex, SC, United States) using 3D printer (Cube X trio) in an animal model. Materials and Methods Eighteen New Zealand rabbits were divided into three groups with six animals each. Platelet-rich fibrin (PRF) was collected from the venous blood and preserved. Bone defect (4 mm × 2 mm) without disturbing the bone marrow was created and filled with bone graft material (group 1–Ossifi, group 2–powdered PLA, and group 3–3D-printed PLA), over which PRF membranes were placed. The graft material and the barrier were stabilized using resorbable sutures, and all the animals were maintained for 4, 8, and 12 weeks, after which they were euthanized, and bone samples were retrieved. Retrieved bone samples were subjected to radiological and histological analysis. Results The radiographic and histological changes of 3D-printed PLA in comparison with other two materials (Ossifi and powdered PLA) seemed to have a significant difference. Conclusion 3D-printed PLA scaffolds showed positive signs of bone regeneration around the material in continuity defects. PLA material can be a promising alternative bone regenerative material.

Awareness Towards Fixed Orthodontic Treatment Among High School Students in Perambur - A Survey

“…Thus, it becomes highly important for us to identify the awareness of fixed orthodontic treatment among the school students in perambur so that they can prevent further malocclusion and cause further complications and moreover its their esthetic appearance and confidence that plays an important role for a high school going children in perambur. Previously our department has published extensive research on various aspects of prosthetic dentistry ('evaluation of Corrosive Behavior of Four nickel-chromium Alloys in Artificial Saliva by Cyclic Polarization Test:An in vitro Study ganapathy, Kannan and Venugopalan, 2017;Jain, 2017aJain, , 2017branganathan, ganapathy and Jain, 2017;Ariga et al, 2018;gupta, Ariga and deogade, 2018;Anbu et al, 2019;Ashok and ganapathy, 2019;duraisamy et al, 2019;Varghese, ramesh and Veeraiyan, 2019), this vast research experience has inspired us to research the awareness of Fixed orthodontic treatment among school children in perambur.…”

KAP On Connective Tissue Grafts in Implant Aest

“…However, the anatomical limits, occlusal space management, occlusal stability and periodontal status must be considered prior to the planning of the esthetic parameters for the future prosthetic restoration (forna and Agop-forna, 2019) Aesthetic outcomes are important for successful dental implantation which are determined by the smile and lip line. previously our department has published extensive research on various aspects of prosthetic dentistry ('evaluation of Corrosive Behavior of four nickel-chromium Alloys in Artificial Saliva by Cyclic polarization Test:An in vitro Study ', 2017;ganapathy, kannan and venugopalan, 2017;Jain, 2017aJain, , 2017bRanganathan, ganapathy and Jain, 2017;Ariga et al, 2018;gupta, Ariga and Deogade, 2018;Anbu et al, 2019;Duraisamy et al, 2019;Ashok and ganapathy, 2019;varghese, Ramesh and veeraiyan,), this vast research experience has inspired us to do research on connective tissue graft in implant aesthetics. The aim of the study is to evaluate the knowledge attitude and practise on connective tissue used in implant aesthetics.…”

KAP on Haemostasis and Usage of Styptics Among Dental Students

“…Previously our department has published extensive research on various aspects of prosthetic dentistry ('evaluation of Corrosive Behavior of Four nickelchromium Alloys in Artificial Saliva by Cyclic Polarization Test:An in vitro Study ', 2017;ganapathy, Kannan and Venugopalan, 2017;Jain, 2017aJain, , 2017bRanganathan, ganapathy and Jain, 2017;Ariga et al, 2018;gupta, Ariga and Deogade, 2018;Anbu et al, 2019;Ashok and ganapathy, 2019;Duraisamy et al, 2019;Varghese, Ramesh and Veeraiyan, 2019), this vast research experience has inspired us to research about various methods practiced and general knowledge of halitosis among dental students. The main purpose of this study being that by determining the frequently practiced methods in management of hemorrhage and a better insight on the degree of understanding of homeostasis and use of haemostatic agents.…”