Comparison of the effects of x-ray and gamma irradiation on engineering thermoplastics

Brouwer, Hans de

doi:10.1016/j.radphyschem.2022.109999

Cited by 11 publications

(8 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The three tests performed on PBT did not detect any differences between the samples, within the detection limits of each technique used, indicating any X‐ray or gamma radiation‐induced effects on PBT in this dose range are minimal. The findings agree with literature reporting high stability of PBT to gamma and X‐ray radiation 9,25 …”

Section: Resultssupporting

confidence: 92%

“…The findings agree with literature reporting high stability of PBT to gamma and X-ray radiation. 9,25 F I G U R E 3 Example of product separated into components, each tested separately.…”

Section: Materials Assessmentsmentioning

confidence: 99%

“…Previous studies have shown that X-ray and gamma irradiation yield similar impacts to polymer properties. 9 Fintzou et al described the impact of high energy X-ray and gamma radiation on the physicochemical and mechanical properties of polypropylenes; Girard-Perier et al compared the gamma, X-ray irradiation and e-beam impacts on the polymer modification of multilayer films for biopharmaceutical applications; Menzel et al studied X-ray and gamma impacts on the extractables profiles of a multilayer film and a copolyester Tritan material; and all studies indicate X-ray and gamma having similar impacts. [10][11][12][13] However, most of the published results have limited types of polymers, and focus on one specific type of applications, for example, film and SU technologies devices.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Impact of X‐ray irradiation as an equivalent alternative to gamma for sterilization of single‐use bioprocessing polymers

Grzelak

Jeffkins

et al. 2023

Biotechnology Progress

View full text Add to dashboard Cite

Irradiation sterilization of polymeric pharmaceutical processing systems and medical devices, an essential healthcare technology, is facing critical business continuity challenges, driving the need to qualify equivalent alternative irradiation technologies, such as X‐ray. Whereas the underlying there is a paucity of cross‐industry published data evaluating X‐ray irradiation effects on plastics as compared to gamma irradiation. That leads to regulatory uncertainty in the levels of costly validation data regulators will require and overall apprehension in the rate of X‐ray irradiation adoption. The present study evaluates the impact of X‐ray versus gamma irradiation on a wide range of polymers with more than 36 single‐use (SU) components, using a comprehensive set of industry aligned methods for characterization of bioprocess polymers. Whereas many of these techniques readily demonstrate changes in polymer properties following irradiation, all of the polymers evaluated demonstrated that the impact of X‐ray irradiation was to the same degree or less as compared to gamma. Increased publication of studies evaluating the impact to polymers of X‐ray versus gamma irradiation is critical to leveraging extensive, existing validation packages on bioprocess systems and medical devices obtained following gamma irradiation, and essential in qualifying X‐ray irradiation as an equivalent technology (i.e., materials are impacted to the same extent or less than gamma) that can overcome business continuity challenges to ensure continued availability of critical patient therapies.

show abstract

Section: Resultssupporting

confidence: 92%

“…The findings agree with literature reporting high stability of PBT to gamma and X-ray radiation. 9,25 F I G U R E 3 Example of product separated into components, each tested separately.…”

Section: Materials Assessmentsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Impact of X‐ray irradiation as an equivalent alternative to gamma for sterilization of single‐use bioprocessing polymers

Grzelak

Jeffkins

et al. 2023

Biotechnology Progress

View full text Add to dashboard Cite

show abstract

“…2 X-rays sterilization is considered as one possible technology which could absorb this market growth as proven by growing research on gamma rays and X-rays equivalency. [5][6][7][8] X-ray and gamma rays exhibit very similar features as both are photons but produced from different sources. 8 Gamma rays refer to the production of photons by radioactive disintegration, whereas X-rays are produced with electron accelerator through conversion of electron energy into photons via Bremsstrahlung effect.…”

Section: Introductionmentioning

confidence: 99%

Radical detection and electron‐spin resonance (ESR) monitoring in polymer materials irradiated with gamma and X‐rays: Polyethylene and polypropylene

Krieguer,

Marque,

Dorey

et al. 2024

J of Applied Polymer Sci

View full text Add to dashboard Cite

When ionizing radiations interact with polymers, free radicals are generated and are known to be the initiating species for the modification in materials. Monitoring and identifying free radicals after irradiation allow assessing the impact of X‐rays and gamma rays on materials. A comparative study has been performed on materials made from polypropylene and polyethylene after irradiation by the two irradiation technologies. Electron spin resonance (ESR) signal has been monitored up to 380 days when signal was still present. ESR signals, concentration profiles, and kinetics were observed after X‐rays and gamma rays.

show abstract

“…Although a recent study [21] has found that both x-ray and gamma radiation at the same dose possesses the same effects on the thermoplastics, the x-ray energies and equipment size limit its application to dense materials, thick products, and complex geometries, besides the needing for a power supply, which is also a shortcoming. Therefore, gamma-radiography of 3D-printed thermoplastics could be introduced as an alternative to XCT.…”

Section: Introductionmentioning

confidence: 99%

Radiographic testing of 3D-printed thermoplastics using Am-241 as a gamma-ray source

Alaqab

Siddiq

Banoqitah

et al. 2023

Mater. Res. Express

View full text Add to dashboard Cite

The industrial production of 3D printing is known as additive manufacturing (AM), in which a computer controls the process of producing 3D objects. Although X-ray computed radiography (XCT) is extensively used in the quality control and testing of additive manufacturing products, the gamma-ray radiography capabilities for these applications still need to be investigated. This study aimed to evaluate the performance of gamma-ray radiography using americium-241 (Am-241) as the gamma source. Here, we inspected fused deposition three-dimensional (3D) modeling products produced from polylactic acid (PLA) as thermoplastic samples. Radiographic testing of 3D-printed thermoplastic samples was performed using Monte Carlo simulations and validated by experimental studies. We used Am-241 (gamma-ray source) to conduct simulations and experiments investigations; two simulations were used: one by using 59.6 keV energy of gamma-ray and the other using all gamma-ray energies, including 16.96 keV, 26.3446 keV% 2.31 up to 662.40 keV. Also, we performed the X-ray radiography test to be used as a standard. The results showed that the defect detectability in the 3D-printed PLA samples using Am-241 as a gamma-ray source is comparable to that of X-ray results. This study concluded that the Am-241 could be used as the gamma-ray source to perform the radiography test for the products produced by 3D-printed thermoplastics.

show abstract

Comparison of the effects of x-ray and gamma irradiation on engineering thermoplastics

Cited by 11 publications

References 11 publications

Impact of X‐ray irradiation as an equivalent alternative to gamma for sterilization of single‐use bioprocessing polymers

Impact of X‐ray irradiation as an equivalent alternative to gamma for sterilization of single‐use bioprocessing polymers

Radical detection and electron‐spin resonance (ESR) monitoring in polymer materials irradiated with gamma and X‐rays: Polyethylene and polypropylene

Radiographic testing of 3D-printed thermoplastics using Am-241 as a gamma-ray source

Contact Info

Product

Resources

About