Comparison of the Effects of High- and Low-frequency Repetitive Transcranial Magnetic Stimulation on Upper Limb Hemiparesis in the Early Phase of Stroke

Sasaki, Nozomu; Mizutani, Saneyuki; Kakuda, Wataru; Abo, Masahiro

doi:10.1016/j.jstrokecerebrovasdis.2011.10.004

Cited by 107 publications

(112 citation statements)

References 26 publications

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“…Similarly, the present study found that improvement of motor function of the affected upper limb in the early phase of stroke was significantly larger in patients treated with HF-rTMS, than in those treated with LF rTMS [17]. Recently, Gao et al [18] reported that infarct volumes of an acute stroke rat model were reduced significantly after 7 days of HFrTMS (20 Hz on the lesional hemisphere).…”

Section: Discussionsupporting

confidence: 82%

Effects of High Frequency Repetitive Transcranial Magnetic Stimulation on Function in Subacute Stroke Patients

Cha¹,

Kim²,

Nam³

et al. 2014

Journal of Magnetics

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The aim of the present study was to examine the effects of high and low frequency repetitive transcranial magnetic stimulation on motor cortical excitability and the balance function in subacute stroke patients. Twenty-four subjects were randomly assigned to either the high frequency (HF) rTMS group, or the low frequency (LF) rTMS group, with 12 subjects each. All subjects received routine physical therapy. In addition, both groups performed a total of 20 sessions of rTMS for 20 minutes, once a day, 5 times per week, for a 4-week period. In the HF rTMS group, 10 Hz rTMS was applied daily to the hotspot of the lesional hemisphere; and in the LF rTMS group, 1 Hz rTMS was applied daily to the hotspot of the nonlesional hemisphere. Motor cortex excitability was determined by motor evoked potentials, and the balance function was evaluated by use of the Balance Index (BI) and the Berg Balance Scale (BBS), before and after the intervention. The change rate in the value of each variable differed significantly between the two groups ( p<0.05). Furthermore, significant differences were observed between all post-test variables of the two groups ( p<0.05). In the HF rTMS, significant differences were found in all the pre-and post-test variables ( p<0.05). On the other hand, in the LF rTMS, significant difference was observed only between the pre-and post-test results of BI and BBS ( p<0.05). The findings demonstrate that HF rTMS can be more helpful in improving the motor cortical excitability and balance function of patients with subacute stroke treatment than LF rTMS, and that it may be used as a practical adjunct to routine rehabilitation.

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Section: Discussionsupporting

confidence: 82%

Effects of High Frequency Repetitive Transcranial Magnetic Stimulation on Function in Subacute Stroke Patients

Cha¹,

Kim²,

Nam³

et al. 2014

Journal of Magnetics

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“…rTMS is one of the new approaches of clinical intervention for recovery of exercise function among patients with stroke, which noninvasively stimulates the cerebral cortex to cause depolarization in brain cells. This implies that the iterative stimulation of rTMS changes irritability of the cerebral cortex, which contributes to the functional recovery of patients with stroke [7,9].…”

Section: Discussionmentioning

confidence: 99%

“…Repetitive transcranial magnetic stimulation (rTMS) is a method of noninvasive stimulation of the damaged area of the brain, whereby stimulation of the brain can be performed either selectively or directly [6,7].…”

Section: Introductionmentioning

confidence: 99%

The Effects of Repetitive Transcranial Magnetic Stimulation Integrated Mirror Therapy on the Gait of Chronic Stroke Patients

Cha¹,

Kim²

2015

Journal of Magnetics

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This study was conducted to determine the effects of repetitive transcranial magnetic stimulation (rTMS) integrated mirror therapy on the gait of post-stroke patients. Thirty patients who were six months post-stroke were assigned to either the experimental group (n = 15) or the control group (n = 15). Stroke patients in the experimental group underwent rTMS and mirror therapy for the lower limbs, while those in the control group underwent rTMS and sham therapy. Participants in both groups received therapy five days per week for four weeks. A significant difference in post-training gains for the single support phase, step length, stride length and velocity was observed between the experimental group and the control group (p < 0.05). The experimental group showed a significant increment in the single support phase, step length, stride length, swing phase, velocity, cadence, double support phase and step width as compared to pre-intervention (p < 0.05). The control group showed a significant increment in step length, velocity, cadence and step width compared to preintervention (p < 0.05). Further investigation of the availability and feasibility of rTMS integrated mirror therapy for post-stroke patients as a therapeutic approach for gait rehabilitation is warranted.

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“…Daily high-frequency rTMS of the ipsilesional M1 is tolerable, and modestly facilitated motor recovery in the paralytic hand of subacute stroke patients [4]. Many studies in Japan found improved motor function of the upper limbs in chronic stroke patients [12,16]. LF-TMS over the unaffected hemisphere may be more beneficial than rTMS over the affected hemisphere.…”

Section: Tdcs Study In Post-stroke and Parkinson's Diseasementioning

confidence: 99%

“…Recent studies indicated that compared with LF-rTMS, HF-rTMS applied to the lesional hemisphere in the early phase of stroke was more beneficial for motor function of the affected upper limb [12].…”

Section: Noninvasive Brain Stimulationmentioning

confidence: 99%

Non-Invasive Brain Stimulation (TMS/tDCS) and Rehabilitation for Stroke and Parkinson’s

Matsuda¹,

Manji²,

Amimoto³

et al. 2017

Neurological Physical Therapy

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The aim of this study was to clarify and compare the efficacies of rehabilitation using transcranial direct current stimulation (tDCS) and continuous theta burst stimulation (cTBS), a form of repetitive transcranial magnetic stimulation (rTMS), in convalescing stroke and Parkinson's disease patients. For both types of stimuli, kinetic analysis and performance analysis of upper limb motor paralysis and gait analysis showed an increase in speed of movement, and an improvement in performance was observed. Both stimuli resulted in significant improvement compared with a sham stimulus. Change in speed of movement and performance was observed with both tDCS and cTBS, but there was not a significantly large difference between the stimuli. Improved movement due to reduction of excessive tension caused by spasticity was observed. In patients with Parkinson's disease, gait speed and step length were increased. It is suggested that performance was improved because movement became smoother. The efficacy of tDCS and cTBS in patients with motor disorders caused by stroke or Parkinson's disease will probably be further improved when combined with physical therapy.

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Comparison of the Effects of High- and Low-frequency Repetitive Transcranial Magnetic Stimulation on Upper Limb Hemiparesis in the Early Phase of Stroke

Cited by 107 publications

References 26 publications

Effects of High Frequency Repetitive Transcranial Magnetic Stimulation on Function in Subacute Stroke Patients

Effects of High Frequency Repetitive Transcranial Magnetic Stimulation on Function in Subacute Stroke Patients

The Effects of Repetitive Transcranial Magnetic Stimulation Integrated Mirror Therapy on the Gait of Chronic Stroke Patients

Non-Invasive Brain Stimulation (TMS/tDCS) and Rehabilitation for Stroke and Parkinson’s

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