Comparison of the effect of hemodialysis and peritoneal dialysis in the treatment of end-stage renal disease

Abstract

Objective: To compare the clinical effects of hemodialysis (HD) and peritoneal dialysis (PD) in the treatment of end-stage renal disease (ESRD) patients.
 Methods: Clinical data of ESRD patients who received HD (n=74) and PD (n=77) for more than 12 months in the First People’s Hospital of Tonglu County from October 2020 to November 2021 were retrospectively selected. Renal function indexes, blood pressure, and complication rates in the two groups before the first dialysis and at the end of the observation period were compared.
 Results: After the dialysis, the urea nitrogen (BUN) levels decreased in both groups, and were significantly lower in the PD group compared to the HD group. Urea clearance index (Kt/V) increased, and were significantly higher in the PD group compared to the HD group (P<0.05). After the dialysis, albumin (ALB) and cardiac ejection fraction (EF) levels significantly increased, and ALB levels were significantly higher in the HD group while EF levels were significantly higher in the PD group (P<0.05). Levels of whole parathyroid hormone (iPTH), systolic blood pressure, and diastolic blood pressure indicators in both groups decreased compared to before the dialysis, and were significantly lower in the PD group compared to the HD group of patients (P<0.05). PD was associated with significantly lower total incidence of complications compared to HD (P<0.05).
 Conclusions: Peritoneal dialysis is more effective in maintaining the hemodynamic stability for ESRD patients, reducing blood pressure level, improving the clearance rate of molecular substances, and protecting the renal function of patients compared to hemodialysis.
 doi: https://doi.org/10.12669/pjms.39.6.8056
 How to cite this: Zhao Y. Comparison of the effect of hemodialysis and peritoneal dialysis in the treatment of end-stage renal disease. Pak J Med Sci. 2023;39(6):---------. doi: https://doi.org/10.12669/pjms.39.6.8056
 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Association between the geriatric nutritional risk index and clinical outcomes among peritoneal dialysis patients: A meta-analysis

“…Currently, there are more than 1000,000 PD patients globally, accounting for 10% to 15% of dialysis patients. [ 1 , 2 ] It has been reported that up to 75% of patients with ESRD exhibit varying degrees of protein-energy wasting. [ 3 ] Among patients undergoing maintenance PD, the substantial loss of protein in the dialysate increases the susceptibility to malnutrition compared to that in hemodialysis patients.…”