Comparison of the clinical effectiveness of the 433 MHz lucite cone applicator with that of a conventional waveguide applicator in applications of superficial hyperthermia

Rietveld, P. J. M.; Putten, Wim L.J. van; Zee, Jacoba van der; Rhoon, Gerard C. van

doi:10.1016/s0360-3016(98)00443-x

Cited by 42 publications

(22 citation statements)

References 25 publications

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“…In the US, the most common device is the microwave waveguide, a simple rectangular or circular metal structure that guides EM waves from a single monopole feed out the open aperture which is at least a half wavelength in largest dimension. Waveguide antennas are commercially available from 7.5 to 24 cm, designed for use at approved Industrial Scientific and Medical (ISM) band frequencies of 915 or 2450 MHz in the US, (67)(68)(69)(70) or 430-434 MHz in Europe (71)(72) and Asia. (73)(74) CLINICAL HYPERTHERMIA…”

Section: Superficial Heatingmentioning

confidence: 99%

Hyperthermia, Radiation and Chemotherapy: The Role of Heat in Multidisciplinary Cancer Care

Hurwitz

Stauffer

2014

Seminars in Oncology

119

104

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Section: Superficial Heatingmentioning

confidence: 99%

Hyperthermia, Radiation and Chemotherapy: The Role of Heat in Multidisciplinary Cancer Care

Hurwitz

Stauffer

2014

Seminars in Oncology

119

104

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“…Proper permittivity ε rLHM and permeability µ rLHM of LHM can be defined by setting ω pe , ω pm and loss factor δ in (1) and (2). To match the water bolus, we may set ω pe =9ω, ω pm = 1.414ω, ω = 2πf and δ = 3.3×10 5 (1) and (2) so that ε rLHM ≈ −80 + j1.4 × 10 −3 , µ rLHM ≈ −1 + j8.57 × 10 −5 for the LHM lens.…”

Section: Methodsmentioning

confidence: 99%

“…For subcutaneous cancer which occurs in a small region, external single-element applicators such as waveguide [2] and specially designed antennas [3,4] can be used for hyperthermia treatment. Generally, single-element applicator will provide Gaussianshaped power distribution with the highest intensity of the beam located directly in front of the applicators.…”

Section: Introductionmentioning

confidence: 99%

Superficial Tumor Hyperthermia With Flat Left-Handed Metamaterial Lens

Gong¹,

Wang²

2009

PIER

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Abstract-Flat left-handed metamaterial (LHM) lens can generate appropriate focusing spot in biological tissue as required in microwave tumor hyperthermia treatment. By using single flat LHM lens to concentrate microwave in a mass of tissue covered by water bolus, microwave hyperthermia scheme is proposed for superficial tumor hyperthermia. The power distribution in tissue is simulated by finitedifference time-domain method, and the thermal pattern is calculated by solving the bio-heat transfer equation. It is demonstrated that, by using a flat LHM lens of thickness of 4 cm to concentrate microwave of 2.45 GHz, a temperature above 42 • C can be achieved and maintained in one hour in a tissue region of about 1.0 cm in width and 1.2 cm in depth in tissue with the source amplitude of 43.44 V/cm, which is suitable for superficial tumor hyperthermia. By adjusting the position of microwave source, the heating zone in tissue can be adjusted in both the lateral and depth direction in tissue. The influence of fat layer, effects of water bolus and microwave frequency on hyperthermia, is investigated as well.

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“…The efforts to develop better heating and thermometry techniques should be expanded. Further research should aim at improving existing techniques [66][67][68] and also developing new techniques or devices to be able to adequately heat more tumour sites. Much attention should be given to the development and verification of hyperthermia treatment planning systems [69][70][71] and to the development of non-invasive thermometry [72][73].…”

Section: Heating Technique and Thermometrymentioning

confidence: 99%

The Kadota Fund International Forum 2004–Clinical group consensus*

Zee

Vujašković

Kondo

et al. 2008

International Journal of Hyperthermia

105

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The results from experimental studies indicate that hyperthermia is both an effective complementary treatment to, and a strong sensitiser of, radiotherapy and many cytotoxic drugs. Since the first international hyperthermia conference in 1975, Washington DC, techniques to increase tumour temperature have been developed and tested clinically. Hyperthermia can be applied by several methods: local hyperthermia by external or internal energy sources, perfusion hyperthermia of organs, limbs, or body cavities, and whole body hyperthermia. The clinical value of hyperthermia in combination with other treatment modalities has been shown by randomised trials. Significant improvement in clinical outcome has been demonstrated for tumours of the head and neck, breast, brain, bladder, cervix, rectum, lung, oesophagus, for melanoma and sarcoma. The addition of hyperthermia resulted in remarkably higher (complete) response rates, accompanied by improved local tumour control rates, better palliative effects, and/or better overall survival rates. Toxicity from hyperthermia cannot always be avoided, but is usually of limited clinical relevance. In spite of these good clinical results, hyperthermia has received little attention. Problems with acceptance concern the limited availability of equipment, the lack of awareness concerning clinical results, and the lack of financial resources. In this paper the most relevant literature describing the clinical effects of hyperthermia is reviewed and discussed, and means to overcome the lack of awareness and use of this modality is described.

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Comparison of the clinical effectiveness of the 433 MHz lucite cone applicator with that of a conventional waveguide applicator in applications of superficial hyperthermia

Cited by 42 publications

References 25 publications

Hyperthermia, Radiation and Chemotherapy: The Role of Heat in Multidisciplinary Cancer Care

Hyperthermia, Radiation and Chemotherapy: The Role of Heat in Multidisciplinary Cancer Care

Superficial Tumor Hyperthermia With Flat Left-Handed Metamaterial Lens

The Kadota Fund International Forum 2004–Clinical group consensus*

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