Comparison of the Benefit Feeling Rate Based on the Sho of OTC Kakkonto, Cold Remedy and Cold Remedy with Kakkonto Combination Product

Abstract

Kakkonto (KK), a traditional Japanese Kampo formulation for cold and flu, is generally sold as an OTC pharmaceuticals used for self-medication. Kampo formulations should be used according to the Shosymptoms of Kampo medicine. These symptoms refer to the subjective symptoms themselves. Although with OTC pharmaceuticals, this is often not the case. We surveyed the relationship of agreement of Sho with the benefit feeling rate (BFR) of patients who took KK (n 555), cold remedies with KK (CK, n 315), and general cold remedies (GC, n 539) using internet research. BFR of a faster recovery was greater in participants who took the medication early and who had confidence in their physical strength in all treatment groups. BFR was significantly higher in the GC group than in the KK group for patients with headache, runny nose, blocked nose, sneezing, and cough. BFR was also significantly higher in the GC group than in the CK group for headache (males) and cough (females). BFR was the highest in the KK group for stiff shoulders. All cold remedies were more effective when taken early, and the larger the number of Sho that a patient had, the greater the BFR increased. Therefore, a cold remedy is expected to be most effective when there are many cold symptoms and when it is taken at an early stage of the common cold.

Discrepancies between patients’ and pharmacists’ perceptions of the role of community pharmacists as advisors on the use of pharmaceuticals in Japan: A comparison prior to and following revision of the Pharmacists’ Act

“…During inspection of questionnaire responses, questionnaires with the same response selected for Q1 through Q12 were defined as insincere responses and excluded from analysis. 19 Data were extracted from patient questionnaire response results according to the flow shown in Supplemental Figure S3(a). Only respondents who regularly visit community pharmacies were the target of this study, and respondents, who irregularly submit prescriptions (for colds and other acute diseases) and insincere respondents, were excluded from analysis.…”

Bodily distress syndrome after receiving vaccines: A case report

“…Amitriptyline has been used for various pain syndromes including fibromyalgia . Kakkonto can be used for stiff shoulders . Keishikaryukotsuboreito has been used for anxiety disorder, functional palpitation, dizziness, and various other symptoms associated with anxiety .…”

Sho-Based Kampo Medicine Combined With Assisted Reproductive Technology Is Effective for Refractory Infertility and Early Recurrent Miscarriage: A Case Report

“…Especially, the abdominal examination is unique to Japan, and considered to be one of the most important approaches ( 6 ). Several studies have reported that the most suitable formula is chosen for a patient after determining Sho as a Kampo concept ( 3 , 5 , 7 , 8 ). For example, Okita et al ( 8 ) described their observations from a clinical trial that involved selected patients who met the criteria of Kakkonto- Sho , and demonstrated that it is more effective than conventional remedies.…”