Comparison of the applicability of electromembrane extraction and liquid‐phase microextraction for extraction of non‐polar basic drugs from different biological samples: Using clozapine as the model analyte
Jianhua Xiong,
Linxin Tian,
Xiantao Shen
et al.
Abstract:Understanding and comparing the applicability of electromembrane extraction (EME) and liquid‐phase microextraction (LPME) is crucial for selecting an appropriate microextraction approach. In this work, EME and LPME based on supported liquid membranes were compared using biological samples, including whole blood, urine, saliva, and liver tissue. After optimization, efficient EME and LPME of clozapine from four biological samples were achieved. EME provided higher recovery and faster mass transfer for blood and … Show more
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