Comparison of the analgesic efficacy of periarticular infiltration and pericapsular nerve group block for total hip arthroplasty: a randomized, non-inferiority study

Does pericapsular nerve group block have limited analgesia at the initial post-operative period? Systematic review and meta-analysis

“…Based on the Cochrane risk of the bias assessment tool, the quality of the included studies ranged from low to high quality with seven studies of low quality [15][16][17][18][19][20][21]; two of moderate quality [22,23]; and six high-quality studies [24][25][26][27][28][29]. Risk of bias graph and summary of quality assessment domains of included studies are shown in Figs.…”

“…Studies included were highly different in terms of the time of intervention, main indication, and volume of injectate. Regarding the time of intervention and main indication; five studies [ 17 , 18 , 24 , 26 , 27 ] used PENG technique to position patients for spinal anesthesia in addition to post-operative pain control; seven studies [ 19 – 23 , 25 , 29 ] used it preoperatively for post-operative pain control; two [ 16 , 28 ] used it postoperatively for pain management; and one study [ 15 ] used it for analgesia in the emergency department with no association to the operation time. Regarding the dose of injectate; all studies reported using 20 ml of volume injectate to perform PENG block except six studies; three of them [ 19 , 21 , 28 ] used 30 ml; and one [ 26 ] used 25 ml of volume.…”

“…Patient Satisfaction score was reported in seven studies [ 18 , 19 , 21 , 23 , 25 , 26 , 29 ] and all of them favored PENG technique. Although it’s a subjective outcome; it may reflect the strong analgesic effect of the technique.…”

“…In another scenario, we excluded studies with a high risk of bias [15,16,[18][19][20][21]. The overall SMD did not change significantly (SMD -0.59; 95% CI [-0.79 to -0.39]; p > 0.00001; low grade of evidence; Fig.…”

The Effects of Periarticular Injection Cocktail in Postoperative Analgesia after Bilateral Unicompartmental Knee Arthroplasty

“…and injecting them around the joints by local infiltration anesthesia (LIA) technology to play the role of postoperative analgesia [ 12 ]. Cocktail injection anesthesia has been widely used in clinical practice, and studies have shown that this method is ideal for analgesia in TKA [ 13 ], rhinoplasty [ 14 ], and spinal fusion [ 15 ]. A meta-analysis by Li et al [ 16 ], on the efficacy of multimodal cocktail periarticular injections with additional corticosteroids in TKA, showed that multimodal cocktail periarticular injections with glucocorticoids reduced the intensity of early resting pain and increased early knee mobility after knee arthroplasty.…”