Comparison of the anaesthesia combinations racemic-ketamine/medetomidine and S-Ketamine/medetomidine in syrian golden hamsters (mesocricetus auratus)

Erhardt, W.; Wohlrab, S; Kiliç, Nuh; Werner, Christian; Henke, Julia

doi:10.1046/j.1467-2987.2001.temp.doc.x-i1

Cited by 15 publications

(21 citation statements)

References 1 publication

(1 reference statement)

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“…Animals showed large individual variation and similar recovery times in both groups. This is in contrast to research in other species (Erhardt et al. 2001; Kiliç & Henke 2004).…”

Section: Discussioncontrasting

confidence: 83%

“…Higher incidences of uncoordinated or involuntary movements when using racemic ketamine in comparative studies with S(+)‐ketamine in different species have been reported previously (White et al. 1982; Erhardt et al. 2001; Kiliç & Henke 2004; Larenza et al.…”

Section: Discussionsupporting

confidence: 52%

“…Since a short recovery is an important factor in field wild animal anaesthesia, it was decided to compare a racemic ketamine -medetomidine protocol with an S(+)-ketamine -medetomidine protocol. It has been reported previously in other species that S(+)ketamine has significantly less undesired side effects during recovery than racemic ketamine (White et al 1982;Erhardt et al 2001;Kiliç & Henke 2004;Rossetti et al 2008).…”

Section: Introductionmentioning

confidence: 84%

“…It has been reported previously in other species that S(+)‐ketamine has significantly less undesired side effects during recovery than racemic ketamine (White et al. 1982; Erhardt et al. 2001; Kiliç & Henke 2004; Rossetti et al.…”

Section: Introductionmentioning

confidence: 86%

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Comparison of S(+)-ketamine and ketamine, with medetomidine, for field anaesthesia in the European brown hare (Lepus europaeus)

Gerritsmann

Stalder

Seilern-Moy

et al. 2012

Veterinary Anaesthesia and Analgesia

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“…Animals showed large individual variation and similar recovery times in both groups. This is in contrast to research in other species (Erhardt et al. 2001; Kiliç & Henke 2004).…”

Section: Discussioncontrasting

confidence: 83%

Section: Discussionsupporting

confidence: 52%

Section: Introductionmentioning

confidence: 84%

Section: Introductionmentioning

confidence: 86%

See 2 more Smart Citations

Comparison of S(+)-ketamine and ketamine, with medetomidine, for field anaesthesia in the European brown hare (Lepus europaeus)

Gerritsmann

Stalder

Seilern-Moy

et al. 2012

Veterinary Anaesthesia and Analgesia

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“…According to Wright (1982), the α 2 ‐agonist xylazine in the X/K combination is responsible for this prolongation of the surgical tolerance. Considering the duration of the entire anaesthesia period (time from injection of the anaesthetics to the re‐occurrence of the righting reflex), a clearly marked prolongation of the recovery time could be seen in animals receiving the X/K combination compared with M/K and MMF, which is in accordance with Jehle (1979) and Erhardt et al. (2001).…”

Section: Discussionsupporting

confidence: 84%

Anaesthesia with Midazolam/Medetomidine/Fentanyl in Chinchillas (Chinchilla lanigera) Compared to Anaesthesia with Xylazine/Ketamine and Medetomidine/Ketamine

Henke

Baumgartner²,

Röltgen³

et al. 2004

Journal of Veterinary Medicine Series A

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We studied four different drug regimes for anaesthetic management in chinchillas and evaluated and compared their cardiovascular and respiratory effects. In this randomized, cross-over experimental study, seven adult chinchillas, five females, two males [515 +/- 70 (SD) g] were randomly assigned to one of the following groups: group 1 [midazolam, medetomidine and fentanyl (MMF), flumazenil, atipamezole and naloxone (FAN); MMF-FAN] received 1.0 mg/kg midazolam, 0.05 mg/kg medetomidine and 0.02 mg/kg fentanyl i.m., and for reversal 0.1 mg/kg flumazenil, 0.5 mg/kg atipamezole and 0.05 mg/kg naloxone s.c. after 45 min; group 2 (MMF) 1.0 mg/kg midazolam, 0.05 mg/kg medetomidine and 0.02 mg/kg fentanyl i.m.; group 3 [xylazine/ketamine (X/K)] 2.0 mg/kg xylazine and 40.0 mg/kg ketamine i.m.; and group 4 [medetomidine/ketamine (M/K)] 0.06 mg/kg medetomidine and 5.0 mg/kg ketamine i.m. Reflexes were judged to determine anaesthetic stages and planes. Anaesthesia with X/K and M/K was associated with a prolonged surgical tolerance and recovery period. By reversing MMF, recovery period was significantly shortened (5 +/- 1.3 min versus 40 +/- 10.3 min in MMF without FAN, 73 +/- 15.0 min in X/K, and 31 +/- 8.5 min in M/K). Without reversal, MMF produced anaesthesia lasting 109 +/- 16.3 min. All combinations decreased respiratory and heart rate but compared with X/K and M/K, respiratory and cardiovascular complications were less in the MMF groups. Focussing on the clinical relevance of the tested combinations, completely reversible anaesthesia showed two major advantages: anaesthesia can be antagonized in case of emergency and routinely shortens recovery. In small animals particularly these advantages lead to less complications and discomfort and thus often can be lifesaving. As all analgesic components (medetomidine and fentanyl) are reversed, postoperative analgesia should be provided before reversal of anaesthesia.

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Clinical experience using a combination of dexmedetomidine, ketamine, midazolam and hydromorphone for general anaesthesia in two winter white dwarf hamsters (Phodopus sungorus) undergoing surgical facial procedures

Sarvi

Eshar

2022

Vet Record Case Reports

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A 4-month-old, male winter white dwarf hamster and an adult, male winter white dwarf hamster of unknown age were presented for surgical procedures of the face. An injectable anaesthesia protocol with DKMH (dexmedetomidine 0.1 mg/kg, ketamine 20 mg/kg, midazolam 1 mg/kg and hydromorphone 0.4 or 0.8 mg/kg) was administered subcutaneously to anaesthetise each hamster. Anaesthesia was induced in less than 1 minute and a surgical plane of anaesthesia was maintained for the duration of the procedure for both hamsters. Postoperatively, flumazenil (0.1 mg/kg) and atipamezole (1 mg/kg) were administered subcutaneously and the hamsters recovered uneventfully without anaesthetic-related complications.

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Comparison of the anaesthesia combinations racemic-ketamine/medetomidine and S-Ketamine/medetomidine in syrian golden hamsters (mesocricetus auratus)

Cited by 15 publications

References 1 publication

Comparison of S(+)-ketamine and ketamine, with medetomidine, for field anaesthesia in the European brown hare (Lepus europaeus)

Comparison of S(+)-ketamine and ketamine, with medetomidine, for field anaesthesia in the European brown hare (Lepus europaeus)

Anaesthesia with Midazolam/Medetomidine/Fentanyl in Chinchillas (Chinchilla lanigera) Compared to Anaesthesia with Xylazine/Ketamine and Medetomidine/Ketamine

Clinical experience using a combination of dexmedetomidine, ketamine, midazolam and hydromorphone for general anaesthesia in two winter white dwarf hamsters (Phodopus sungorus) undergoing surgical facial procedures

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