Comparison of the accuracy of magnetic resonance imaging and positron emission tomography/computed tomography in the presurgical detection of lymph node metastases in patients with uterine cervical carcinoma

Abstract

Ontogenetic samples of endocranial volumes (EVs) from great apes and humans are critical for understanding the evolution of the brain growth pattern in the hominin lineage. However, high quality ontogenetic data are scarce, especially for nonhuman primates. Here, we provide original data derived from an osteological collection of a wild population of Pan troglodytes verus from the Taï Forest National Park, Ivory Coast. This sample is unique, because age, sex, and pedigree information are available for many specimens from behavioral observations in the wild. We scanned crania of all 30 immature specimens and 13 adult individuals using high‐resolution computed tomography. We then created virtual casts of the bony braincase (endocasts) to measure EVs. We also measured cranial length, width, and height and attempted to relate cranial distances to EV via regression analysis. Our data are consistent with previous studies. The only neonate in the sample has an EV of 127 cm3 or 34% of the adult mean. EV increases rapidly during early ontogeny. The average adult EV in this sample is 378.7 ± 30.1 cm3. We found sexual dimorphism in adults; males seem to be already larger than females before adult EV is attained. Regressions on cranial width and multiple regression provide better estimates for EV than regressions on cranial length or height. Increasing the sample size and compiling more high quality ontogenetic data of EV will help to reconcile ongoing discussions about the evolution of hominin brain growth. Am J Phys Anthropol 147:319–325, 2012. © 2011 Wiley Periodicals, Inc.

Ovarian Metastasis and other Ovarian Neoplasms in Women with Cervical Cancer Stage IA-IIA

“…The specificity of MRI to determine bladder invasion was significantly higher than that of CT (91% vs 73%). A prospective study revealed that Positron Emission Tomography/Computed Tomography (PET/CT) has more sensitivity in detection of lymph node metastasis than MRI (57.6% vs 30.3%) but no statistic difference in specificity (92.6% vs 92.6%) and accuracy (85.1% vs 72.7%) (Choi et al, 2006). In spite of excluding from the FIGO clinical staging investigations, CT or MRI, have clinical benefit in pre-operative assessment of early-stage cervical cancer.…”

Comparison of modified Cherney incision and vertical midline incision for management of early stage cervical cancer

“…Moreover, cervical cancer with intra-abdominal lesions are inoperative, and cytoreductive surgery does not have an advantage other than lymph node dissection. It is also reported by Choi et al 6 that PET-CT scan has high sensitivity in detecting pelvic lymph node and para-aortic lymph node metastasis. Therefore it is rarely required to expose the upper abdomen.…”

Treatment of cervical cancer: the importance of a multidisciplinary team approach

“…By providing metabolic imaging information, this technique has demonstrated a high accuracy (85.1%) and specifi city (92.6%) for predicting lymph node involvement [8], confi rming its value in locoregional staging. PET-CT could be used as a tool in the delineation of tumour volumes and the preparation of patient treatment plans, especially when integrated with virtual simulation [9].…”