Comparison of temporal changes in psychological distress after hematopoietic stem cell transplantation among the underlying diseases of Japanese adult patients

Abstract

Background: Although hematopoietic stem cell transplantation (HSCT) can potentially cure some hematological malignancies, patients who undergo HSCT experience psychological distress. However, there have been few studies on the short-term influence of HSCT on psychological distress.

A prospective study of the relationship between sense of coherence, depression, anxiety, and quality of life of haematopoietic stem cell transplant patients over time

“…Given patients' increased vulnerability in the acute phase post‐transplantation, some studies have explored medical, demographic, and psychosocial factors impacting on the trajectory of distress and QoL during this period. For example, research has indicated that transplant type, disease, gender, age, and living circumstances were associated with differing trajectories of distress and QoL in the early post‐transplantation period . It has also been suggested that physical functioning was better predicted by medical factors during the first 2 weeks post‐transplantation .…”