Comparison of Sulfur Hexafluoride 20% versus Air Tamponade in Descemet Membrane Endothelial Keratoplasty

Güell, José L.; Morral, Mercè; Gris, Óscar; Elíes, Daniel; Manero, Felicidad

doi:10.1016/j.ophtha.2015.05.013

Cited by 95 publications

(90 citation statements)

References 39 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…11 Eventually, this promising approach could reduce the amount of gas filling needed to provide adequate support for the graft during the crucial period after surgery. A recent study by Güell et al 15 has found that using 20% SF 6 gas leads to a lower rebubbling rate after DMEK (12.8% with air vs. 2.4% with SF 6 gas) with a bubble size comparable to that of the larger bubble group in this study. Terry et al 14 have also recently investigated the usage of 20% SF 6 gas.…”

Section: Discussionsupporting

confidence: 66%

Anterior Chamber Air Bubble to Achieve Graft Attachment After DMEK

Ćirković

Beck

Weller

et al. 2016

Cornea

View full text Add to dashboard Cite

show abstract

Section: Discussionsupporting

confidence: 66%

Anterior Chamber Air Bubble to Achieve Graft Attachment After DMEK

Ćirković

Beck

Weller

et al. 2016

Cornea

View full text Add to dashboard Cite

show abstract

“…A recent study of 44 patients who underwent DSEK compared SF 6 with air for graft attachment and noted that, although patients who received air had five graft detachments, there were no detachments reported in the group that received SF 6 (8) . Additionally, Guell et al, recently demonstrated reduced detachment rates with SF 6 from those with air in their series, and no effect on corneal endothelial cell counts was observed (9) . In the present study, we compared graft detachment rates between SF 6 and air for intraocular tamponade in DMEK.…”

Section: Resultados: a Taxa De Descolamento Do Botão Endotelial Foi Dmentioning

confidence: 79%

“…A recent in vitro study, however, found no significant difference between SF 6 and air on endothelial cell counts or toxicity of corneal endothelial cells (14) . Additionally, Guell et al found no difference in endothelial cell counts between use of SF 6 or air ≤3years after DMEK (9) . One weakness of our study was that the SF 6 procedures followed the air procedures chronologically because detachment rates have been found to diminish with experience of the surgeon (15) .…”

Section: Discussionmentioning

confidence: 98%

“…Their rebubbling criteria were separation of donor Descemet membrane causing central corneal edema affecting vision and/or evidence of progressive separation of the graft over successive visits. Guell et al noticed a similar rebubbling rate but stated that they also had detachments that did not fit their criteria for rebubbling (9) . In our study, all of the partial graft detachments were determined to fit our criteria for rebubbling, which included central corneal edema affecting vision.…”

Section: Discussionmentioning

confidence: 98%

See 1 more Smart Citation

Comparison of 20% sulfur hexafluoride with air for intraocular tamponade in Descemet membrane endothelial keratoplasty (DMEK)

Botsford¹,

Vedana²,

Cope³

et al. 2016

Arquivos Brasileiros De Oftalmologia

View full text Add to dashboard Cite

Purpose: To compare the effect of 20% sulfur hexafluoride (SF 6 ) with that of air on graft detachment rates for intraocular tamponade in Descemet membrane endothelial keratoplasty (DMEK). Methods: Forty-two eyes of patients who underwent DMEK by a single surgeon (A.S.J.) at Wilmer Eye Institute between January 2012 and 2014 were identified; 21 received air for intraocular tamponade and the next consecutive 21 received SF 6 . The main outcome measure was the graft detachment rate; univariate and multivariate analyses were performed. Results: The graft detachment rate was 67% in the air group and 19% in the SF 6 group (p<0.05). No complete graft detachments occurred, and all partial detachments underwent intervention with injection of intraocular air. The percentages of eyes with 20/25 or better vision were not different between the groups (67% vs. 71%). Univariate analysis showed significantly higher detachment rates with air tamponade (OR, 8.50; p<0.005) and larger donor graft size (OR, 14.96; p<0.05). Multivariate analysis with gas but not graft size included showed that gas was an independent statistically significant predictor of outcome (OR, 6.65; p<0.05). When graft size was included as a covariate, gas was no longer a statistically significant predictor of detachment but maintained OR of 7.81 (p=0.063) similar to the results of univariate and multivariate analyses without graft size. Conclusion:In comparison with air, graft detachment rates for intraocular tamponade in DMEK were significantly reduced by 20% SF 6 .

show abstract

“…10,11,15,25 With an improved surgical technique, the number is reported as low as 12%. 26 The lack of standardized criteria for rebubbling in DMEK makes it difficult to systematically compare the rate of rebubbling between various techniques from different …”

Section: Discussionmentioning

confidence: 99%