Comparison of stored red blood cell washing techniques for priming extracorporeal circuits

Sasaki, Jun; Tirotta, Christopher F.; Lim, Hyunsoo; Kubes, Kathleen; Salvaggio, Jane; Hannan, Robert L.; Burke, Redmond P.; Ojito, Jorge

doi:10.1177/0267659117730134

Cited by 9 publications

(12 citation statements)

References 6 publications

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“…21,22 Guideline 13.1 : When priming with exogenous blood, the use of prebypass ultrafiltration (preBUF) or washed red blood cells should be used during priming procedure. 23 -28 Guideline 13.2 : The perfusionist should consider matching prime composition to the individual patient values. …”

Section: Resultsmentioning

confidence: 99%

“…Guideline 13.1 : When priming with exogenous blood, the use of prebypass ultrafiltration (preBUF) or washed red blood cells should be used during priming procedure. 23 -28…”

Section: Resultsmentioning

confidence: 99%

“…To assist with optimization of prime composition, prebypass ultrafiltration (preBUF) or red cell washing are guidelines used during priming procedures to obtain more physiologic levels of glucose, potassium, and sodium when compared to banked blood. [26][27][28] Standard 16. Fluid Management.…”

Section: Review Of New Standardsmentioning

confidence: 99%

See 2 more Smart Citations

American Society of ExtraCorporeal Technology: Development of Standards and Guidelines for Pediatric and Congenital Perfusion Practice (2019)

Oldeen

Angona

Hodge

et al. 2020

World J Pediatr Congenit Heart Surg

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The development of standards and guidelines by professional societies offers clinicians guidance toward providing evidence-based care. The ultimate goals of standards and guidelines are to standardize care and improve patient safety and outcomes while also minimizing risk. The American Society of ExtraCorporeal Technology (AmSECT) currently offers perfusionists several clinical resources, primarily the Standards and Guidelines for Perfusion Practice; however, no document exists specific to pediatric perfusion. Historically, the development of a pediatric-specific document has been limited by available scientific evidence due to smaller patient populations, sample sizes, and variable techniques among congenital perfusionists. In the current setting of evolving clinical practices and increasingly complex cardiac operations, a subcommittee of pediatric perfusionists developed the Standards and Guidelines for Pediatric and Congenital Perfusion Practice. The development process included a comprehensive literature review for supporting evidence to justify new recommendations or updates to the existing AmSECT Adult Standards and Guidelines document. Multiple revisions incorporating feedback from the community led to a finalized document accepted by the AmSECT membership and made available electronically in May 2019. The Standards and Guidelines for Pediatric and Congenital Perfusion Practice is an essential tool for pediatric perfusionists and serves as the backbone for institutionally based protocols, promotes improved decision-making, and identifies opportunities for future research and collaboration with other disciplines. The purpose of this manuscript is to summarize the process of development, the content, and recommended utilization of AmSECT’s Standards and Guidelines for Pediatric and Congenital Perfusion Practice.

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Section: Resultsmentioning

confidence: 99%

“…Guideline 13.1 : When priming with exogenous blood, the use of prebypass ultrafiltration (preBUF) or washed red blood cells should be used during priming procedure. 23 -28…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

American Society of ExtraCorporeal Technology: Development of Standards and Guidelines for Pediatric and Congenital Perfusion Practice (2019)

Oldeen

Angona

Hodge

et al. 2020

World J Pediatr Congenit Heart Surg

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Section: Centrifugation-based Technologiesmentioning

confidence: 97%

“…In a direct comparison, CATS system generated washed RBCs with unchanged potassium levels and little hemolysis, unlike units washed with the COBE 2991 45. CATS was also able to produce RBC concentrates at a higher hematocrit than COBE 2991 and most other conventional discontinuous-flow autotransfusion devices 37,45. When testing for the removal of fat cells from salvaged blood, CATS surpassed discontinuous systems (eg, Cell Saver 5) and was on par with the Cell Save Elite featuring an integrated fat reduction program 46.…”

Section: Centrifugation-based Technologiesmentioning

confidence: 99%

Traditional and emerging technologies for washing and volume reducing blood products

Lu¹,

Lezzar²,

Vörös³

et al. 2019

JBM

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Millions of blood components including red blood cells, platelets, and granulocytes are transfused each year in the United States. The transfusion of these blood products may be associated with adverse clinical outcomes in some patients due to residual proteins and other contaminants that accumulate in blood units during processing and storage. Blood products are, therefore, often washed in normal saline or other media to remove the contaminants and improve the quality of blood cells before transfusion. While there are numerous methods for washing and volume reducing blood components, a vast majority utilize centrifugation-based processing, such as manual centrifugation, open and closed cell processing systems, and cell salvage/autotransfusion devices. Although these technologies are widely employed with a relatively low risk to the average patient, there is evidence that centrifugation-based processing may be inadequate when transfusing to immunocompromised patients, neonatal and infant patients, or patients susceptible to transfusion-related allergic reactions. Cell separation and volume reduction techniques that employ centrifugation have been shown to damage blood cells, contributing to these adverse outcomes. The limitations and disadvantages of centrifugation-based processing have spurred the development of novel centrifugation-free methods for washing and volume reducing blood components, thereby causing significantly less damage to the cells. Some of these emerging technologies are already transforming niche applications, poised to enter mainstream blood cell processing in the not too distant future.

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Blood Transfusion and Acute Kidney Injury After Total Aortic Arch Replacement for Acute Stanford Type A Aortic Dissection

Líu

et al. 2022

Heart, Lung and Circulation

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Comparison of stored red blood cell washing techniques for priming extracorporeal circuits

Cited by 9 publications

References 6 publications

American Society of ExtraCorporeal Technology: Development of Standards and Guidelines for Pediatric and Congenital Perfusion Practice (2019)

American Society of ExtraCorporeal Technology: Development of Standards and Guidelines for Pediatric and Congenital Perfusion Practice (2019)

Traditional and emerging technologies for washing and volume reducing blood products

Blood Transfusion and Acute Kidney Injury After Total Aortic Arch Replacement for Acute Stanford Type A Aortic Dissection

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