Comparison of steroid antibiotic pack and 10% ichthammol glycerine pack in relieving pain of acute otitis externa in children

Adhikari, Prakash; Bhatta, Rishi; Bhandari, Sukmit; Pyakurel, Manita

doi:10.1016/j.ijporl.2011.01.004

Cited by 6 publications

(4 citation statements)

References 22 publications

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“…13 Adhikari also made a similar observation to Ahmed et al in concluding that steroid antibiotic combination caused earlier relief of symptoms and less hospital visits as compared to icthammol. 21 In our study of 250 patients all the patients of both groups had tenderness and discharge initially. On the seventh day of presentation, while tenderness was significantly more in icthammol group (p-value 0.042) discharge was almost equally reduced in both groups (p-value 0.08).…”

Section: Discussionmentioning

confidence: 58%

Comparison of the Efficacy of Antibiotic-Steroid and Ichthammol Glycerine Wick in Treatment of Acute Otitis Externa

Khan

Butt

Riaz

et al. 2021

PAFMJ

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Objective: To compare the efficacy of steroid antibiotic wick with Ichthammol Glycerol wick in the management of Acute Otitis Externa in terms of tenderness and clearance of discharge/debris. Study Design: Quasi-experimental study. Place and Duration of Study: ENT Out Patient department of Combined Military Hospital Peshawar and Hayatabad Medical Complex Peshawar, from May to Nov 2018. Methodology: A total of 250 patients were included and divided into two groups of 125 each. After necessary suction clearance topical Ciprofloxacin/Dexamethasone (Cipotec-D) wick was placed in auditory canal of group A patients and topical Glycerol/Ichthammol wick was placed in group B. Follow up visits were done on 3rd and 7th day of starting the treatment. Results: Group A patients responded better in terms of tenderness (88%) however both groups had similar response in terms of discharge reduction (7.2% vs 6.4%). In terms of efficacy neither of the treatment proved more efficacious compared to the other (p-value 0.058). Conclusion: While steroid antibiotic wick is significantly more efficient in terms reducing tenderness, in terms of overall efficacy and discharge reduction Ichthammol/glycerol is equally effective.

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Section: Discussionmentioning

confidence: 58%

Comparison of the Efficacy of Antibiotic-Steroid and Ichthammol Glycerine Wick in Treatment of Acute Otitis Externa

Khan

Butt

Riaz

et al. 2021

PAFMJ

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“…Shrestha K et al Another similar study has been done by Adhikari using 10% IG pack and steroid-an bio c ointment pack in children. It showed sta s cally significant decrease in number of visits 27 in steroid an bio c group. Jamalullah M et al also showed significant reduc on in pain on third day in steroidan bio c pack group than in 10% IG pack group.…”

Section: Discussionmentioning

confidence: 90%

Efficacy of 10% Ichthammol Glycerine Pack and Steroid-antibiotic Pack for Relieving Pain in Acute Otitis Externa. A Comparative Study.

Shrestha

Shah

Sapkota

2019

Birat J. Health Sci.

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Introduction: Otitis externa is a common painful condition presents with generalized infection of external auditory canal, typically reveals erythema and edema of the skin. Aural packing plays an important role in relieving the pain and edema. For packing, either we impregnated with 10% Ichthammol glycerine or steroid-antibiotic ointment. Objective: To compare the efficacy of 10% Ichthammol Glycerine pack with steroid-antibiotic ointment pack for relieving the pain in acute otitis externa. Methodology: A prospective, non-randomized clinical trial was carried out in 94 patients at Birat Medical College and Teaching Hospital, Biratnagar, Nepal from February 2018 to July 2018. Patients diagnosed with acute otitis externa were included in this study, where 47 patients were treated with 10% IG pack and remaining 47 patients treated with a combination steroid antibiotic ointment pack. Before aural packing was carried out, pain was assessed using visual analogue scale (VAS). Both groups of patients were evaluated after 48 hours for assessment of pain. Results: The total number of patients included in this study was 94. Among them 41 (43.6%) were male and 53(56.4%) were female where male and female ratio was 1:1.29. Majority of the patients were below 40 years (83%). Treatment with steroid-antibiotic ointment pack had significant reduction in pain after 48 hours post treatment, none of them had severe pain, 4(8.5%) had moderate pain remaining and 43(91.4%) had only mild pain. Whereas in patients treated with 10% IG pack 1(2.1%) had severe pain, 14(29.7%) had moderate pain and 32(68%) had mild pain. There was statistically significant decrease in pain with steroid-antibiotic pack. Conclusions: Both treatment modalities are effective but this study showed steroid-antibiotic ointment pack, the combined therapy is more effective than 10% IG pack for relieving the pain in acute otitis externa.

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“…We are the first to review non‐pharmaceuticals and IG, an antimicrobial agent that reduces canal oedema and pain 29,30 . Two of three RCTs favoured topical antibiotics over IG, however we could not perform meta‐analysis due to heterogeneity, and we also had to exclude three further RCTs for including oral antibiotics alongside the interventions for all patients 31–33 …”

Section: Discussionmentioning

confidence: 99%

Antibiotics versus non‐antibiotic treatments for acute otitis externa: A systematic review and meta‐analysis

Traglia

Tudor-Green

Muzaffar

et al. 2023

Clinical Otolaryngology

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BackgroundOtitis externa is a condition causing inflammation of the outer ear canal, which presents with itching, discharge and pain. Most cases of acute otitis externa are caused by bacterial infection and are thus treated with antibiotics.This systematic review and meta‐analysis of randomised controlled trials aims to assess the effectiveness of topical non‐antibiotic treatments compared to topical antibiotic treatment for the treatment of acute otitis externa.MethodsSystematic review and meta‐analysis databases searched: Cochrane Library including ClinicalTrials.gov; MEDLINE; World Health Organisation International Clinical Trials Registry Platform and Web of Science to identify randomised clinical trials evaluating topical antibiotics and topical non‐antibiotic agents in adults and children with acute otitis externa. Non‐antibiotic therapeutics for comparison with topical antibiotics included antiseptics, steroids, non‐pharmaceuticals and astringents.ResultsSeventeen trials were eligible for inclusion, with 10 combined in meta‐analysis. Data could be pooled comparing antiseptic and steroid monotherapies with topical antibiotic agents. There were no significant differences in cure rates in any pairwise comparisons. Individually, the majority of studies favoured topical antiseptics or steroids over antibiotics, however these differences were not significant when pooled in meta‐analysis.ConclusionAntiseptic, steroid and antibiotic monotherapies are all effective for the management of acute otitis externa. There is insufficient evidence to suggest that topical antiseptic or steroid agents are superior or inferior to topical antibiotics.

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Comparison of steroid antibiotic pack and 10% ichthammol glycerine pack in relieving pain of acute otitis externa in children

Cited by 6 publications

References 22 publications

Comparison of the Efficacy of Antibiotic-Steroid and Ichthammol Glycerine Wick in Treatment of Acute Otitis Externa

Comparison of the Efficacy of Antibiotic-Steroid and Ichthammol Glycerine Wick in Treatment of Acute Otitis Externa

Efficacy of 10% Ichthammol Glycerine Pack and Steroid-antibiotic Pack for Relieving Pain in Acute Otitis Externa. A Comparative Study.

Antibiotics versus non‐antibiotic treatments for acute otitis externa: A systematic review and meta‐analysis

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