Comparison of standardversuspopulation-specific handgrip strength cut-off points in the detection of probable sarcopenia after launch of EWGSOP2

Abstract

Objective: We aimed to compare European Working Group on Sarcopenia in Older People (EWGSOP2)-suggested and population-specific handgrip strength (HGS) thresholds to detect probable sarcopenia and their associations with physical-performance measures and frailty. Methods: A retrospective cross-sectional observational-study included geriatrics outpatients applied to a university-hospital. HGS, timed up and go test (TUG), and usual gait speed (UGS) were assessed. Frailty was screened by FRAIL-scale. Results: A total of 1825 older adults were included (mean age, 74.5 þ 7.0 years; 68.8% female). Prevalence of low-HGS were 12.2% by the EWGSOP2-recommended (27/16 kg) cut-offs and 37.5% by population-specific cut-offs (35/20 kg) (p<.001). When low-HGS was defined by EWGSOP2 suggested cut-offs, low-HGS was associated with impaired UGS, (odds ratio [OR] ¼ 3.8, 95% confidence interval [CI]: 2.0-6.9, p<.001); impaired TUG, (OR ¼ 4.6, 95% CI: 2.4-8.8, p<.001); and frailty (OR ¼ 20.9, 95% CI: 8.3-53.0, p<.001). Similarly, low HGS determined by population-specific cut-off points was associated with impaired UGS (OR ¼ 3.1, 95% CI: 2.1-6.9, p<.001); impaired TUG (OR ¼ 6.0, 95% CI: 3.0-11.8, p<.001); and frailty (OR ¼ 7.3, 95% CI: 4.1-13.0, p<.001). Conclusions: Application of EWGSOP2-recommended standard HGS-cut-offs showed successful application in-practice. However, use of standard HGS cut-offs may result in underdiagnosis of probable sarcopenia. Therefore, we suggest that, whenever available, use of population-specific cut-offs for HGS may be better for correctly identifying older adults at risk.

Association Between Muscle Strength and Cystatin C-Based Estimated Glomerular Filtration Rate Among Middle-Aged and Elderly Population: Findings Based on the China Health and Retirement Longitudinal Study (CHARLS), 2015

“…Recent research found that the new cut-offs of HGS by EWGSOP2 identified very small percentage of the elderly with probable sarcopenia and may lead to underdiagnose sarcopenia. 37 In our study, the number of participants who were identified as low muscle strength was considerably lower with EWGOSP2-recommended (27/16 kg) cut-offs than with the EWGOSP-recommended (30/20 kg) cutoffs (1005 participants, 8.1% versus 2125 participants, 17.1%). To identify the probable sarcopenia in older adults and avoid underdiagnosis, we used cut-offs by EWGSOP (30/20 kg).…”

Spanish translation, cultural adaptation and validation of the SarQoL®: a specific health-related quality of life questionnaire for sarcopenia

“…However, our Spanish questionnaire did show good discrimination according to muscle function (muscle strength or physical performance). This suggests that quality of life, at least in our participants, is better correlated to muscle function than to muscle mass and emphasized the issues raised with measuring muscle mass and defining cut-off points [ 2 , 48 ]. Our cut-off point of SPPB ≤ 9 as an inclusion criterion is based on the design of the SPRINTT trial (based on the LIFE trial) [ 28 , 49 ] and SPPB < 8 as an indicator of low physical performance and sarcopenia severity according to the EWGSOP2 when we classified our participants according to their physical function.…”

Kanser Tanili Hastalarin Kemoterapi̇ Öncesi̇ Ve Sonrasi Yaşa Göre Sarkopeni̇ Ve Beslenme Durumunun Değerlendi̇ri̇lmesi̇

“…El kavrama kuvveti ölçümü için Jamar® dijital el dinamometresi kullanılmıştır. Kas kuvveti ölçümleri Bahat ve arkadaşlarının Türkiye için belirlediği kesim noktaları değerlerine göre kıyaslanmıştır (22). Buna göre el kavrama kuvveti erkekler için <35 kg, kadınlar içinse <20 ise "yetersiz" olarak değerlendirilmiştir.…”