Comparison of Standard Automated Perimetry, Frequency-Doubling Technology Perimetry, and Short-Wavelength Automated Perimetry for Detection of Glaucoma

Liu, Shu; Lam, S.S.; Weinreb, Robert N.; Ye, Cong; Cheung, Carol Y.; Lai, Gilda; Lam, Dennis S C; Leung, Christopher Kai-Shun

doi:10.1167/iovs.11-7795

Cited by 56 publications

(45 citation statements)

References 29 publications

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“…3; Johnson et al, 1993;Landers et al, 2003;Liu et al, 2011;Sample et al, 2006). These tests aim to target subpopulations of retinal ganglion cells by evaluating specific aspects of visual function, such as motion perception, contrast sensitivity, or color vision (Sample and Weinreb, 1990;Sample et al, 1988), and thereby reduce the ability of the visual system to use other pathways to compensate.…”

Section: Other Perimetric Devicesmentioning

confidence: 99%

Strategies to improve early diagnosis in glaucoma

Tatham¹,

Medeiros²,

Zangwill³

et al. 2015

Progress in Brain Research

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Early diagnosis and treatment of glaucoma is important to reduce the risk of progressive and irreversible visual loss. The key to diagnosis is recognition of morphological changes to the optic nerve head and retinal nerve fiber layer, but in some patients, functional abnormalities are detected first. This review describes recent innovations with the potential to improve the early detection of glaucoma. Developments in imaging include novel optic nerve head metrics such as Bruch's membrane opening-minimum rim width, enhanced ability to quantify inner layers of the glaucomatous macula, and ability to image deep optic nerve head structures, including the lamina cribrosa. Developments in detection of early glaucomatous functional loss include novel perimetric tests using frequency-doubling technology and flicker-defined form stimuli. Methods to combine results of structural and functional assessments are also presented that may improve early detection of glaucoma. KeywordsGlaucoma, Optical coherence tomography, OCT, Perimetry, Spectral domain, Early diagnosis Glaucoma is a leading cause of blindness, affecting more than 70 million people worldwide, of whom approximately 10% are bilaterally blind (Quigley and Broman, 2006). Glaucomatous visual losses can be prevented with early diagnosis and treatment; however, affected individuals are typically asymptomatic until later stages of the disease and a large proportion of those affected remain undiagnosed. Population-level surveys suggest only 10-50% of people with glaucoma are aware that they have the condition and consequently there are a large number of people Progress in Brain Research, Volume 221, ISSN 0079-6123, http://dx

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Section: Other Perimetric Devicesmentioning

confidence: 99%

Strategies to improve early diagnosis in glaucoma

Tatham¹,

Medeiros²,

Zangwill³

et al. 2015

Progress in Brain Research

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“…Short wavelength-automated perimetry (SWAP) has been available since the early 1990s and has been extensively studied. However, recent data have questioned the initial findings that SWAP was more sensitive to early glaucoma damage than SAP 11 12. Longitudinal data regarding the performance of frequency doubling technology (FDT) perimetry are limited.…”

Section: Introductionmentioning

confidence: 99%

Measuring rates of structural and functional change in glaucoma

Nouri‐Mahdavi

2014

Br J Ophthalmol

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Glaucoma is a progressive optic neuropathy. Hence, most glaucomatous eyes demonstrate signs of deterioration over time despite what may appear to be adequate treatment. The main goal of glaucoma treatment is to slow the rate of disease so that patients can prolong their functional vision. Therefore, it is important for clinicians caring for patients with glaucoma to be able to estimate rates of change with structural and functional outcomes in their patients. Various trend analysis models have been previously used to estimate rates of decay in glaucoma. The authors discuss the relevant issues and the inherent caveats related to estimating structural and functional rates of change in glaucoma. Patterns of deterioration, testing frequency, and combing structural and functional rates of change are also addressed.

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“…5–7 Although a considerable number of studies have shown that SWAP 8–12 and FDT 10,12–16 results can predict the future onset of visual field loss with SAP, other studies have questioned the advantage of these tests over SAP. 17–20 …”

Section: Introductionmentioning

confidence: 99%

Comparison of Standard Automated Perimetry, Short-Wavelength Automated Perimetry, and Frequency-Doubling Technology Perimetry to Monitor Glaucoma Progression

Wang

et al. 2016

Medicine

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Detection of progression is paramount to the clinical management of glaucoma. Our goal is to compare the performance of standard automated perimetry (SAP), short-wavelength automated perimetry (SWAP), and frequency-doubling technology (FDT) perimetry in monitoring glaucoma progression.Longitudinal data of paired SAP, SWAP, and FDT from 113 eyes with primary open-angle glaucoma enrolled in the Diagnostic Innovations in Glaucoma Study or the African Descent and Glaucoma Evaluation Study were included. Data from all tests were expressed in comparable units by converting the sensitivity from decibels to unitless contrast sensitivity and by expressing sensitivity values in percent of mean normal based on an independent dataset of 207 healthy eyes with aging deterioration taken into consideration. Pointwise linear regression analysis was performed and 3 criteria (conservative, moderate, and liberal) were used to define progression and improvement. Global mean sensitivity (MS) was fitted with linear mixed models.No statistically significant difference in the proportion of progressing and improving eyes was observed across tests using the conservative criterion. Fewer eyes showed improvement on SAP compared to SWAP and FDT using the moderate criterion; and FDT detected less progressing eyes than SAP and SWAP using the liberal criterion. The agreement between these test types was poor. The linear mixed model showed a progressing trend of global MS overtime for SAP and SWAP, but not for FDT. The baseline estimate of SWAP MS was significantly lower than SAP MS by 21.59% of mean normal. FDT showed comparable estimation of baseline MS with SAP.SWAP and FDT do not appear to have significant benefits over SAP in monitoring glaucoma progression. SAP, SWAP, and FDT may, however, detect progression in different glaucoma eyes.

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Comparison of Standard Automated Perimetry, Frequency-Doubling Technology Perimetry, and Short-Wavelength Automated Perimetry for Detection of Glaucoma

Abstract: The performance for glaucoma detection was comparable between FDT perimetry and SAP. FDT perimetry had a higher sensitivity for detecting glaucoma than did SWAP at a comparable level of specificity.

Cited by 56 publications

References 29 publications

Strategies to improve early diagnosis in glaucoma

Strategies to improve early diagnosis in glaucoma

Measuring rates of structural and functional change in glaucoma

Comparison of Standard Automated Perimetry, Short-Wavelength Automated Perimetry, and Frequency-Doubling Technology Perimetry to Monitor Glaucoma Progression

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