Comparison of Single Voxel and Multi Voxel Magnetic Resonance Spectroscopy in Evaluation of Brain Tumors

J, Anith Alfred; F, Abubacker Sulaiman; Shree, Divya; Ahmed, A.I.; Saravanan, K.; Prabhu, Vijay

doi:10.21276/ijcmsr.2018.3.2.9

Cited by 2 publications

(1 citation statement)

References 14 publications

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“…As anticipated, many studies preferred to use the SVS method due to its short acquisition time and higher signal to noise ratio, which would provide good spectral quality [15]. It was argued that MVS offered more accurate information through its capability to yield data from multiple adjacent voxels in a single measurement, thus avoiding errors caused by multiple acquisitions times [16].…”

Section: Spectroscopy Techniquementioning

confidence: 99%

Proton Magnetic Resonance Spectroscopy (1H-MRS) in Studies of Glaucoma: A Scoping Review

Musa¹,

Sidek²,

Hanafiah³

et al. 2021

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Glaucoma is a disease that is chronic in nature and indistinctive at an early stage, leading to late detection. It has become a major public health problem and a leading cause of irreversible blindness worldwide. The proton magnetic resonance spectroscopy (1H-MRS), of late, has been utilised to evaluate metabolites concentration in the brain, especially for detecting neurodegenerative disease. Considering that glaucoma is a neurodegenerative disease, studies on the concentration of metabolites using 1H-MRS in glaucoma patients could be investigated. This scoping review aims to examine the extent, range, and nature of studies on the 1H-MRS technique in glaucoma disease. The literature search was conducted using MEDLINE, CINAHL and SCOPUS, dated from 2000 until 2019. Studies on glaucoma using 1H-MRS were considered. Any processing method used to characterise the metabolite concentration generated by the 1H-MRS protocol has also been considered. Nine full-text studies were yielded after hundreds of literature identification, screening, and eligibility assessment. The included studies sought to determine the feasibility, change, and comparability of metabolite concentrations in glaucoma patients using 1H-MRS with more studies utilising single-voxel spectroscopy (SVS) technique. The chosen anatomy of interest could have been influenced by several criteria, including the association between anatomy and the research query and the volume-sizing capabilities of the 1H-MRS technique. Six (6) metabolites were significantly identified, and quantified, including N-acetyl aspartate, Creatine, Choline, Myo-Inositol, Lactate and Glutamate-Glutamine. This scoping review points out the 1H-MRS application in different types and severity of glaucoma, highlighting the information on the type of patients, the detected metabolites in the anatomy involved, the 1H-MRS technique used and the raw data decipherment processing software. Future studies are needed to validate existing glaucoma studies and to explore the potential of detecting incipient glaucoma.

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Section: Spectroscopy Techniquementioning

confidence: 99%

Proton Magnetic Resonance Spectroscopy (1H-MRS) in Studies of Glaucoma: A Scoping Review

Musa¹,

Sidek²,

Hanafiah³

et al. 2021

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“Role of Spectroscopy in Magnetic Resonance Imaging: A Clinical Review”

Adityan

Selvaganesan²

2021

ijsr

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Magnetic Resonance Spectroscopy (MRS) is used in diagnostic imaging for disease metabolism evaluation. The H MRS is highly used because of the abundance, high sensitivity, etc. The various clinical implementation includes whole-brain MRS is used in measuring metabolites of different brain areas simultaneously. The breast MRS is used in malignant and benign tumors differentiation by the total choline compound. The prostate MRS is used to map the metabolites like citrate, choline, and creatinine. For spinal cord MRS, the myoinositol and N acetyl aspartate were 31 23 1 considered markers for various diseases. The MRS uses nuclei like P, Na, and H for metabolic and biochemical evaluation of cardiac muscles. The liver MRS spectrum has mainly methylene group of lipid, methyl groups of choline, and water. The MRS measures choline, creatinine, lactate, and lipid peaks in uterine leiomyoma and myometrium. Hence there are organ-specic metabolites used as a reference to map the metabolic process by using spectroscopy, making it one of the commonly preferred technique.

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Comparison of Single Voxel and Multi Voxel Magnetic Resonance Spectroscopy in Evaluation of Brain Tumors

Cited by 2 publications

References 14 publications

Proton Magnetic Resonance Spectroscopy (1H-MRS) in Studies of Glaucoma: A Scoping Review

Proton Magnetic Resonance Spectroscopy (1H-MRS) in Studies of Glaucoma: A Scoping Review

“Role of Spectroscopy in Magnetic Resonance Imaging: A Clinical Review”

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