Comparison of sensitization patterns to dust mite allergens between atopic dermatitis patients and dogs, and non-specific reactivity of canine IgE to the storage mite Tyrophagus putrescentiae

Song, Hangyeol; Lee, Jae Hyun; Jeong, Kyoung Yong; Cheon, Doo‐Sung

doi:10.1007/s10493-022-00744-5

Cited by 3 publications

(4 citation statements)

References 28 publications

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“…It is also the third most common mite found in Korean households(Choi et al, 2010;Jeong et al, 2012). The high prevalence of Tyrophagus putrescentiae in this study is consistent with previous research; however,Song et al (2022) indicated that atopic dogs had a lower sensitization rate to T. putrescentiae allergens compared to Dermatophagoides farinae Song et al (2022). also showed that D. farinae, the predominant species, D. pteronyssinus, and T. putrescentiae are significant contributors to CAD in South Korea.…”

supporting

confidence: 91%

Serum allergen-specific and total IgE concentrations in dogs with allergic disorders in South Korea

Yoon,

Lee,

Song

2023

Korean J. Vet. Serv

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Canine atopic dermatitis (CAD) has a genetic basis and is primarily a skin disorder characterized by allergic features. It is caused by an excessive immune response, associated with immunoglobulin E (IgE), to allergens and shows clinical signs of itching and inflammation. The present study evaluated the allergen-specific and total IgE concentration in dogs with allergic disorders. Allergen-specific IgE analysis was performed using a Multiple Allergen Simultaneous Test (MAST) assay, and total IgE analysis was conducted using an ELISA in 82 dogs with CAD. The subjects were divided into two groups: dogs aged ≤3 years and dogs aged >3 years, enabling a comparison of total IgE concentrations between the two age groups. The results showed that the major affecting environmental allergen was Alternaria alternate, and the major affecting dietary allergen was raw chestnut. The results revealed that dogs aged ≤3 years had higher total IgE concentrations than dogs aged >3 years with significant difference. The results of this study can contribute to the diagnosis and treatment of CAD in South Korea.

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confidence: 91%

Serum allergen-specific and total IgE concentrations in dogs with allergic disorders in South Korea

Yoon,

Lee,

Song

2023

Korean J. Vet. Serv

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“…Associations found regarding either sIgE or IDT between dust mites and storage mites [57][58][59] and grass pollen species [60][61][62] were already expected due to cross-reaction. Interestingly, the highest significant correlation (r = 0.967; p < 0.00001) observed in terms of sIgE was found between D. farinae and T. putrescentiae, as suggested by ELISA inhibition studies recently performed by Song et al (2022) [59]. Sometimes, those underlying sensitizations lead to allergy, and sometimes, it does not [42,63,64].…”

Section: Discussionmentioning

confidence: 82%

Survey of Sensitization to Common Fungi in an Allergic Dog Population: The Need for Further Focus on Sensitization and Allergy to Fungi in Veterinary Medicine

Martins

2023

JoF

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Most fungal species are commensals and non-pathogenic to plants, humans, or animals. However, several species of the Alternaria, Aspergillus, Trichophyton, and Microsporum genera are common causes of disease, even for immunocompetent individuals. Besides mucosal damage, fungi may contribute to a skin barrier impairment, favoring sensitization and allergy development. A total of 68 allergic dogs were selected from a veterinary dermatology and allergy outpatient consultation for conditions related to both Malassezia overgrowth and other fungal complications. The allergy diagnosis was made through anamnesis and current clinical criteria, with the involved allergenic species being identified by intradermal tests (IDTs) and allergen-specific immunoglobulin E (sIgE) determination in serum. Dermatophagoides farinae, Dactylis glomerata, and Malassezia pachydermatis showed as the higher sensitization species from house dust mites, grass pollen, and fungi, respectively. Significant correlations at p < 0.05 were found between sensitization to Dactylis glomerata and Phleum pratense grass pollens, Dermatophagoides farinae and Dermatophagoides pteronyssinus, Acarus siro, Tyrophagus putrescentiae, and Lepidoglyphus destructor dust/storage mites, and between fungi like Aspergillus mix and Penicillium or Alternaria alternata. A significant correlation was also found between sensitization to the Aspergillus mix and D. farinae, D. pteronyssinus, or A. siro. Rather severe dermatitis was observed when a positive IDT to Malassezia pachydermatis was found, regardless of the detection of circulating sIgE, allowing us to consider the usefulness of both the IDT and the sIgE for a systematic diagnosis of allergy to fungi.

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“…Associations found regarding sIgE or IDT, between dust and storage mites [56][57][58] and between grass pollen species [59][60][61] were expected as genetic predisposition to develop sensitization as well as cross-reaction occur. Interestingly, the highest significant correlation (r=0.967; p<0.00001) observed in sIgE was found between D. farinae and T. putrescentiae as suggested by ELISA inhibition studies recently performed by Song et. al.…”

Section: Discussionmentioning

confidence: 97%

“…al. (2022) [58]. Sometimes, those underlying sensitizations conduce to allergy and sometimes not [41,62,63].…”

Section: Discussionmentioning

confidence: 99%

Survey of Sensitization to Common Fungi in an Allergic Dog Population

Martins¹

2023

Preprint

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Most fungal species are commensals, not pathogenic for plants, humans, or animals. However, several species from genera Alternaria, Aspergillus, Trichophyton and Microsporum are common causes of disease, even for immunocompetent individuals, contributing to skin barrier impairment. A total of 68 allergic dogs were selected from a veterinary dermatology and allergy outpatient consultation, for conditions related to Malassezia overgrowth or other fungal complications. Allergy diagnosis was made through anamnestic and clinical criteria and allergy-implicated species were identified by intradermal testing (IDT) and serum determination of specific immunoglobulin E (sIgE). Dermatophagoides farinae, Dactylis glomerata and Malassezia pachydermatis showed as the higher sensitization species from each group. Significant correlations at p<0.05 were found between Dactylis glomerata and Phleum pratense grass pollens, Dermatophagoides farinae and Dermatophagoides pteronyssinus, Acarus siro, Tyrophagus putrescentiae and Lepidoglyphus destructor dust/storage mites, and between fungi like Aspergillus mix and Penicillium or Alternaria alternata. A significant correlation was also found between sensitization to Aspergillus mix and D. farinae, D. pteronyssinus or A. siro. Rather severe dermatitis was observed where positive IDT to Malassezia pachydermatis was found, regardless of the presence of circulating sIgE, allowing us to perceive the usefulness of both sIgE and IDT for allergy diagnosis to fungi.

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Comparison of sensitization patterns to dust mite allergens between atopic dermatitis patients and dogs, and non-specific reactivity of canine IgE to the storage mite Tyrophagus putrescentiae

Cited by 3 publications

References 28 publications

Serum allergen-specific and total IgE concentrations in dogs with allergic disorders in South Korea

Serum allergen-specific and total IgE concentrations in dogs with allergic disorders in South Korea

Survey of Sensitization to Common Fungi in an Allergic Dog Population: The Need for Further Focus on Sensitization and Allergy to Fungi in Veterinary Medicine

Survey of Sensitization to Common Fungi in an Allergic Dog Population

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