Comparison of Salmonella enterica Serovar Heidelberg Isolates from Human Patients with Those from Animal and Food Sources

Abstract

Seventy-eight Salmonella enterica serovar Heidelberg isolates from humans were tested for antimicrobial susceptibility, resistance genes, and plasmids and genotyped by pulsed-field gel electrophoresis (PFGE). Most (88%) contained plasmids, and 47% were resistant to antimicrobials. The overall results were compared to those of previous S. Heidelberg studies of food-and animal-related sources, and multiple similarities were observed.

Isolation, molecular identification and antibiogram profiles of Escherichia coli and Salmonella spp. from diarrhoeic cattle reared in selected areas of Bangladesh

“…were able to ferment dextrose, maltose and mannitol with the production of both acid and gas but did not ferment lactose and sucrose and those characteristics of Salmonella spp. were satisfied the statement of Hossain, 2002;Han et al, 2011. The isolated E. coli were found MR and indole test positive but VP test negative which were reported by Merchant and Packer, 1967;Ali et al, 1998;Mishra et al, 2002.…”

Role of egg in food born salmonellosis: A public health issue.

“…The WHO observed an alarming rate increment of resistant Salmonella strains due to the abusive use of antibiotics in poultry farm 46 . The horizontal transmission of virulence genes in multidrug resistant Salmonella strains can increase virulence and invasiveness and it cause high mortality rates 47 . Bangladesh J Med Microbiol Volume 9: Number 1 January, 2015…”

Salmonella Heidelberg Strain Responses to Essential Oil Components

“…Salmonella Heidelberg is one of the most commonly isolated serovars in the U.S. and Canada from clinical cases of salmonellosis, retail meats and livestock (Zhao et al, 2008;Hur, Jawale, & Lee, 2012). While most Salmonella infections are self-limiting and are resolved within a few days, S. Heidelberg tends to cause a significantly higher percentage of invasive infections (Vugia et al, 2004;Han et al, 2011). As a result, antimicrobial therapy is often necessary, making antimicrobial resistance a significant concern.…”

“…Due to the tendency of S. Heidelberg to cause severe extra-intestinal infections (Wilmshurst & Sutcliffe, 1995) such as myocarditis and septicemia (Vugia et al, 2004), the occurrence of S. Heidelberg multidrug resistance strains is of extreme clinical importance. Salmonella Heidelberg strains exhibiting antimicrobial resistance have been isolated from humans, retail meats and food animals (Logue, Sherwood, Olah, Elijah, & Dockter, 2003;Nayak et al, 2004;Kaldhone et al, 2008;Zhao et al, 2008;Lynne, Kaldhone, David, White, & Foley, 2009;Oloya, Doetkott, & Khaitsa, 2009;Han et al, 2011). Studies suggest that poultry-associated S. Heidelberg strains harbor IncFIB, IncA/C, IncH2, and IncI1 plasmids, which may contain genes that confer resistance to several antibiotics such as tetracycline, kanamycin, streptomycin, and sulfonamides (Han et al, 2012).…”

“…Salmonella enterica serovar Heidelberg (S. Heidelberg) ranks fourth among the top five serovars associated with human infections and is responsible for an estimated 84,000 illnesses in the U. S. annually (CDC, 2008;FDA, 2009;Foley et al, 2011;Han et al, 2011). Salmonella Heidelberg is one of the most commonly isolated serovars in the U.S. and Canada from clinical cases of salmonellosis, retail meats and livestock (Zhao et al, 2008;Hur, Jawale, & Lee, 2012).…”